Carotid body hyperplasia and enhanced ventilatory responses to hypoxia in mice with heterozygous deficiency of PHD2.
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HIF hydroxylase pathways in cardiovascular physiology and medicineIron, oxygen, and the pulmonary circulationMolecular mechanisms of action and therapeutic uses of pharmacological inhibitors of HIF-prolyl 4-hydroxylases for treatment of ischemic diseasesPotent and Selective Triazole-Based Inhibitors of the Hypoxia-Inducible Factor Prolyl-Hydroxylases with Activity in the Murine BrainHuman high-altitude adaptation: forward genetics meets the HIF pathway.Clinical iron deficiency disturbs normal human responses to hypoxia.The Zinc Finger of Prolyl Hydroxylase Domain Protein 2 Is Essential for Efficient Hydroxylation of Hypoxia-Inducible Factor α.The von Hippel-Lindau Chuvash mutation in mice causes carotid-body hyperplasia and enhanced ventilatory sensitivity to hypoxiaHuman adaptation to the hypoxia of high altitude: the Tibetan paradigm from the pregenomic to the postgenomic era.Adipocyte pseudohypoxia suppresses lipolysis and facilitates benign adipose tissue expansion.TASK channels in arterial chemoreceptors and their role in oxygen and acid sensing.Carotid body oxygen sensing and adaptation to hypoxia.Regulation of ventilatory sensitivity and carotid body proliferation in hypoxia by the PHD2/HIF-2 pathwayOxygen sensing by the carotid body: mechanisms and role in adaptation to hypoxia.Prolyl hydroxylase domain enzymes: important regulators of cancer metabolism.Hyperplasia and hypertrophy of pulmonary neuroepithelial bodies, presumed airway hypoxia sensors, in hypoxia-inducible factor prolyl hydroxylase-deficient mice.Elevation of iron storage in humans attenuates the pulmonary vascular response to hypoxia.Dynamical compensation in physiological circuitsCardiopulmonary phenotype associated with human PHD2 mutation.Control of breathing and ventilatory acclimatization to hypoxia in deer mice native to high altitudes.PHD2 inactivation in Type I cells drives HIF-2α-dependent multilineage hyperplasia and the formation of paraganglioma-like carotid bodies
P2860
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P2860
Carotid body hyperplasia and enhanced ventilatory responses to hypoxia in mice with heterozygous deficiency of PHD2.
description
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name
Carotid body hyperplasia and e ...... terozygous deficiency of PHD2.
@en
Carotid body hyperplasia and e ...... terozygous deficiency of PHD2.
@nl
type
label
Carotid body hyperplasia and e ...... terozygous deficiency of PHD2.
@en
Carotid body hyperplasia and e ...... terozygous deficiency of PHD2.
@nl
prefLabel
Carotid body hyperplasia and e ...... terozygous deficiency of PHD2.
@en
Carotid body hyperplasia and e ...... terozygous deficiency of PHD2.
@nl
P2093
P2860
P50
P1476
Carotid body hyperplasia and e ...... terozygous deficiency of PHD2.
@en
P2093
Christopher W Pugh
Emma J Hodson
Gillian Douglas
Keith J Buckler
Lynn G Nicholls
Marina Demetriades
Tammie Bishop
P2860
P304
P356
10.1113/JPHYSIOL.2012.247254
P407
P50
P577
2013-05-20T00:00:00Z