The telomere deprotection response is functionally distinct from the genomic DNA damage response.
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Do telomeres adapt to physiological stress? Exploring the effect of exercise on telomere length and telomere-related proteinsMammalian E-type cyclins control chromosome pairing, telomere stability and CDK2 localization in male meiosisSenescence from G2 arrest, revisitedDNA damage to a single chromosome end delays anaphase onsetThe presence of telomere fusion in sporadic colon cancer independently of disease stage, TP53/KRAS mutation status, mean telomere length, and telomerase activityTelomere maintenance mechanisms in cancer: clinical implicationsLINE-1 induces hTERT and ensures telomere maintenance in tumour cell lines.Progerin, the protein responsible for the Hutchinson-Gilford progeria syndrome, increases the unrepaired DNA damages following exposure to ionizing radiation.A basal level of DNA damage and telomere deprotection increases the sensitivity of cancer cells to G-quadruplex interactive compounds.In vivo role of checkpoint kinase 2 in signaling telomere dysfunction.Fungal Ku prevents permanent cell cycle arrest by suppressing DNA damage signaling at telomeres.Mir-23a induces telomere dysfunction and cellular senescence by inhibiting TRF2 expression.An H2A Histone Isotype, H2ac, Associates with Telomere and Maintains Telomere Integrity.Processing by MRE11 is involved in the sensitivity of subtelomeric regions to DNA double-strand breaks.Complex interactions between the DNA-damage response and mammalian telomeres.E-type cyclins modulate telomere integrity in mammalian male meiosisVisualization of Telomere Integrity and Function In Vitro and In Vivo Using Immunofluorescence Techniques.Role of the double-strand break repair pathway in the maintenance of genomic stability.Guarding chromosomes from oxidative DNA damage to the very endTRF2-Mediated Control of Telomere DNA Topology as a Mechanism for Chromosome-End ProtectionRapid induction of alternative lengthening of telomeres by depletion of the histone chaperone ASF1.Stop pulling my strings - what telomeres taught us about the DNA damage response.Antigenic variation in African trypanosomes: the importance of chromosomal and nuclear context in VSG expression control.Evolving concepts of tumor heterogeneity.Disruption of direct 3D telomere-TRF2 interaction through two molecularly disparate mechanisms is a hallmark of primary Hodgkin and Reed-Sternberg cells.Beyond Telomerase: Telomere Instability as a Novel Target for Cancer Therapy.Cell death during crisis is mediated by mitotic telomere deprotectionMolecular mechanisms involved in initiation of the DNA damage response.γH2AX foci on apparently intact mitotic chromosomes: not signatures of misrejoining events but signals of unresolved DNA damageThe long and the short of TRF2 in neurogenesis.Interchromosomal homology searches drive directional ALT telomere movement and synapsis.A 'telomere-associated secretory phenotype' cooperates with BCR-ABL to drive malignant proliferation of leukemic cells.DUB-resistant ubiquitin to survey ubiquitination switches in mammalian cells.Telomere-driven diseases and telomere-targeting therapies.Control of Cellular Aging, Tissue Function, and Cancer by p53 Downstream of Telomeres.Ubiquitination and SUMOylation in Telomere Maintenance and Dysfunction.Mitotic Dysfunction Associated with Aging Hallmarks.Mitotic DNA Damage Response: At the Crossroads of Structural and Numerical Cancer Chromosome Instabilities.Transcription regulation of CDKN1A (p21/CIP1/WAF1) by TRF2 is epigenetically controlled through the REST repressor complex.TRF1 and TRF2 binding to telomeres is modulated by nucleosomal organization.
P2860
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P2860
The telomere deprotection response is functionally distinct from the genomic DNA damage response.
description
2013 nî lūn-bûn
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2013年の論文
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2013年学术文章
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2013年学术文章
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2013年学术文章
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2013年学术文章
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2013年学术文章
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2013年学术文章
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2013年學術文章
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name
The telomere deprotection resp ...... e genomic DNA damage response.
@en
The telomere deprotection resp ...... e genomic DNA damage response.
@nl
type
label
The telomere deprotection resp ...... e genomic DNA damage response.
@en
The telomere deprotection resp ...... e genomic DNA damage response.
@nl
prefLabel
The telomere deprotection resp ...... e genomic DNA damage response.
@en
The telomere deprotection resp ...... e genomic DNA damage response.
@nl
P2860
P1433
P1476
The telomere deprotection resp ...... he genomic DNA damage response
@en
P2093
Jan Karlseder
Laure Crabbe
P2860
P304
P356
10.1016/J.MOLCEL.2013.06.006
P577
2013-07-11T00:00:00Z