about
Molecular mechanisms of Nrf2 regulation and how these influence chemical modulation for disease interventionChemical tuning enhances both potency toward nrf2 and in vitro therapeutic index of triterpenoidsThe clinical potential of influencing Nrf2 signaling in degenerative and immunological disordersNRF2-regulation in brain health and disease: implication of cerebral inflammationChronic Activation of Hepatic Nrf2 Has No Major Effect on Fatty Acid and Glucose Metabolism in Adult MiceThe Keap1-Nrf2 pathway: promising therapeutic target to counteract ROS-mediated damage in cancers and neurodegenerative diseases.Bardoxolone methyl (CDDO-Me) as a therapeutic agent: an update on its pharmacokinetic and pharmacodynamic properties.The effect of ex vivo CDDO-Me activation on nuclear factor erythroid 2-related factor 2 pathway in white blood cells from patients with septic shock.Diabetic nephropathy: the role of inflammation in fibroblast activation and kidney fibrosis.The emerging role of the Nrf2-Keap1 signaling pathway in cancerNRF2-mediated Notch pathway activation enhances hematopoietic reconstitution following myelosuppressive radiation.Sulforaphane Prevents Angiotensin II-Induced Testicular Cell Death via Activation of NRF2.Dimethyl Fumarate ameliorates pulmonary arterial hypertension and lung fibrosis by targeting multiple pathwaysRole of the Nrf2 signaling system in health and disease.Diabetic cardiomyopathy and its prevention by nrf2: current status.The role of modulation of antioxidant enzyme systems in the treatment of neurodegenerative diseases.Dual activities of the anti-cancer drug candidate PBI-05204 provide neuroprotection in brain slice models for neurodegenerative diseases and stroke.Characterization of RA839, a Noncovalent Small Molecule Binder to Keap1 and Selective Activator of Nrf2 Signaling.From the Cover: Zinc Deficiency Worsens and Supplementation Prevents High-Fat Diet Induced Vascular Inflammation, Oxidative Stress, and Pathological Remodeling.Peptide inhibitors of the Keap1-Nrf2 protein-protein interaction with improved binding and cellular activity.Permanent culture of macrophages at physiological oxygen attenuates the antioxidant and immunomodulatory properties of dimethyl fumarate.Nrf2 at the Heart of Oxidative Stress and Cardiac Protection.The triterpenoid RTA 408 is a robust mitigator of hematopoietic acute radiation syndrome in mice.
P2860
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P2860
description
2013 nî lūn-bûn
@nan
2013年の論文
@ja
2013年学术文章
@wuu
2013年学术文章
@zh
2013年学术文章
@zh-cn
2013年学术文章
@zh-hans
2013年学术文章
@zh-my
2013年学术文章
@zh-sg
2013年學術文章
@yue
2013年學術文章
@zh-hant
name
Bardoxolone brings Nrf2-based therapies to light.
@en
Bardoxolone brings Nrf2-based therapies to light.
@nl
type
label
Bardoxolone brings Nrf2-based therapies to light.
@en
Bardoxolone brings Nrf2-based therapies to light.
@nl
prefLabel
Bardoxolone brings Nrf2-based therapies to light.
@en
Bardoxolone brings Nrf2-based therapies to light.
@nl
P2860
P356
P1476
Bardoxolone brings Nrf2-based therapies to light.
@en
P2093
Donna D Zhang
P2860
P304
P356
10.1089/ARS.2012.5118
P577
2013-01-11T00:00:00Z