Inhibition of aquaporin-1 and aquaporin-4 water permeability by a derivative of the loop diuretic bumetanide acting at an internal pore-occluding binding site. - Wikidata - wikimedia - TriplyDB

Inhibition of aquaporin-1 and aquaporin-4 water permeability by a derivative of the loop diuretic bumetanide acting at an internal pore-occluding binding site.

Inhibition of aquaporin-1 and aquaporin-4 water permeability by a derivative of the loop diuretic bumetanide acting at an internal pore-occluding binding site.

http://www.wikidata.org/entity/Q43106571

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Progress in AQP Research and New Developments in Therapeutic Approaches to Ischemic and Hemorrhagic Stroke Detecting Aquaporin Function and Regulation Can Stabilization and Inhibition of Aquaporins Contribute to Future Development of Biomimetic Membranes?Aquaporins: highly regulated channels controlling plant water relations Droplet-based microfluidic platform for measurement of rapid erythrocyte water transport Targeting aquaporin function: potent inhibition of aquaglyceroporin-3 by a gold-based compound Fragment Screening of Human Aquaporin 1 Bumetanide hyperpolarizes madin-darby canine kidney cells and enhances cellular gentamicin uptake by elevating cytosolic Ca(2+) thus facilitating intermediate conductance Ca(2+)--activated potassium channels.Idiopathic cerebrospinal fluid overproduction: case-based review of the pathophysiological mechanism implied in the cerebrospinal fluid production The potential roles of aquaporin 4 in malignant gliomas Aquaporins: important but elusive drug targets.Structure, function and translational relevance of aquaporin dual water and ion channels.Expression of astrocytic genes coding for proteins implicated in neural excitation and brain edema is altered after acute liver failure.Aquaporin-1 translocation and degradation mediates the water transportation mechanism of acetazolamide Aquaporins in cerebrovascular disease: a target for treatment of brain edema?Development of a Novel Ligand, [C]TGN-020, for Aquaporin 4 Positron Emission Tomography Imaging Neuroprotection of Sanhua Decoction against Focal Cerebral Ischemia/Reperfusion Injury in Rats through a Mechanism Targeting Aquaporin 4 Pharmacological blockade of aquaporin-1 water channel by AqB013 restricts migration and invasiveness of colon cancer cells and prevents endothelial tube formation in vitro.Experimental Evaluation of Proposed Small-Molecule Inhibitors of Water Channel Aquaporin-1 AqF026 is a pharmacologic agonist of the water channel aquaporin-1.Aquaporin water channels in the nervous system.Posttraumatic reduction of edema with aquaporin-4 RNA interference improves acute and chronic functional recovery.Rhubarb extract partially improves mucosal integrity in chemotherapy-induced intestinal mucositis.Molecular contributions to neurovascular unit dysfunctions after brain injuries: lessons for target-specific drug development.Aquaporin-1 gene deletion reduces breast tumor growth and lung metastasis in tumor-producing MMTV-PyVT mice.Aquaporin and brain diseases Stimulation of aquaporin-mediated fluid transport by cyclic GMP in human retinal pigment epithelium in vitro Aquaporins: relevance to cerebrospinal fluid physiology and therapeutic potential in hydrocephalus.Cell volume regulation in chondrocytes.The role of aquaporin 4 in the brain.Transporters and channels in cytotoxic astrocyte swelling.The central role of aquaporins in the pathophysiology of ischemic stroke.Aquaporins: New Targets for Cancer Therapy.Aquaporins in Nervous System.Differential Inhibition of Water and Ion Channel Activities of Mammalian Aquaporin-1 by Two Structurally Related Bacopaside Compounds Derived from the Medicinal Plant Bacopa monnieri.Aquaporin-Targeted Therapeutics: State-of-the-Field.The identification of novel, high affinity AQP9 inhibitors in an intracellular binding site.Human AQP1 is a constitutively open channel that closes by a membrane-tension-mediated mechanism A gold coordination compound as a chemical probe to unravel aquaporin-7 function.The aquaporin-4 water channel as a potential drug target in neurological disorders.

P2860

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P2860

Inhibition of aquaporin-1 and aquaporin-4 water permeability by a derivative of the loop diuretic bumetanide acting at an internal pore-occluding binding site.

http://www.wikidata.org/entity/Q43106571

description

2009 nî lūn-bûn

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2009年の論文

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2009年学术文章

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2009年学术文章

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2009年學術文章

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2009年學術文章

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name

Inhibition of aquaporin-1 and ...... l pore-occluding binding site.

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Inhibition of aquaporin-1 and ...... l pore-occluding binding site.

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type

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Inhibition of aquaporin-1 and ...... l pore-occluding binding site.

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Inhibition of aquaporin-1 and ...... l pore-occluding binding site.

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Inhibition of aquaporin-1 and ...... l pore-occluding binding site.

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Inhibition of aquaporin-1 and ...... l pore-occluding binding site.

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Molecular Pharmacology

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Inhibition of aquaporin-1 and ...... l pore-occluding binding site.

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Andrea J Yool

http://www.w3.org/2001/XMLSchema#string

Elizabeth Beckett

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Elton Migliati

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Gary Flynn

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Jennifer S Fang

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Nathalie Meurice

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Pascale DuBois

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Suma Somasekharan

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P2860

Tetraethylammonium block of water flux in Aquaporin-1 channels expressed in kidney thin limbs of Henle's loop and a kidney-derived cell line

Single amino acids in the carboxyl terminal domain of aquaporin-1 contribute to cGMP-dependent ion channel activation

Molecular characterization of an aquaporin cDNA from brain: candidate osmoreceptor and regulator of water balance

Structural basis of water-specific transport through the AQP1 water channel

Inhibition of aquaporin-1 water permeability by tetraethylammonium: involvement of the loop E pore region

Severe alterations of endothelial and glial cells in the blood-brain barrier of dystrophic mdx mice

Identification and structure of a putative Ca2+-binding domain at the C terminus of AQP1.

A regulatory locus of phosphorylation in the N terminus of the Na-K-Cl cotransporter, NKCC1.

Alpha-syntrophin deletion removes the perivascular but not endothelial pool of aquaporin-4 at the blood-brain barrier and delays the development of brain edema in an experimental model of acute hyponatremia.

Microbial MIP channels.

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105-112

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scholarly article

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10.1124/MOL.108.053744

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1

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76

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2009-04-29T00:00:00Z

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24378551

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19403703

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2701455

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