Sonic hedgehog mutations identified in holoprosencephaly patients can act in a dominant negative manner.
about
The molecular genetics of holoprosencephaly.A comprehensive benchmark study of multiple sequence alignment methods: current challenges and future perspectives.The BET bromodomain inhibitor I-BET151 acts downstream of smoothened protein to abrogate the growth of hedgehog protein-driven cancers.Boc modifies the holoprosencephaly spectrum of Cdo mutant mice.Identification of a family of fatty-acid-speciated sonic hedgehog proteins, whose members display differential biological properties.Förster resonance energy transfer-based cholesterolysis assay identifies a novel hedgehog inhibitor.Identification of N-terminal residues of Sonic Hedgehog important for palmitoylation by Hedgehog acyltransferaseThe hedgehog processing pathway is required for NSCLC growth and survivalThe mutational spectrum of holoprosencephaly-associated changes within the SHH gene in humans predicts loss-of-function through either key structural alterations of the ligand or its altered synthesis.Hedgehog signaling and gastrointestinal cancer
P2860
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P2860
Sonic hedgehog mutations identified in holoprosencephaly patients can act in a dominant negative manner.
description
2008 nî lūn-bûn
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2008年の論文
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2008年学术文章
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2008年学术文章
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2008年学术文章
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2008年学术文章
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name
Sonic hedgehog mutations ident ...... in a dominant negative manner.
@en
Sonic hedgehog mutations ident ...... in a dominant negative manner.
@nl
type
label
Sonic hedgehog mutations ident ...... in a dominant negative manner.
@en
Sonic hedgehog mutations ident ...... in a dominant negative manner.
@nl
prefLabel
Sonic hedgehog mutations ident ...... in a dominant negative manner.
@en
Sonic hedgehog mutations ident ...... in a dominant negative manner.
@nl
P2093
P2860
P1433
P1476
Sonic hedgehog mutations ident ...... in a dominant negative manner
@en
P2093
David J Robbins
John A Goetz
Kendall E Black
Nadia Dahmane
Neal S Schilling
Robert Tokhunts
Todd A MacKenzie
Valerie Baubet
Zhen Jane Huang
P2860
P2888
P304
P356
10.1007/S00439-008-0599-0
P50
P577
2008-12-05T00:00:00Z
P5875
P6179
1019296738