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The synthesis of active pharmaceutical ingredients (APIs) using continuous flow chemistryAn overview of the synthetic routes to the best selling drugs containing 6-membered heterocyclesCamera-enabled techniques for organic synthesisAutomating multistep flow synthesis: approach and challenges in integrating chemistry, machines and logic.Facile (triazolyl)methylation of MACOS-derived benzofused sultams utilizing ROMP-derived OTP reagents.Microwave and continuous flow technologies in drug discovery.Palladium-Catalyzed Coupling of Functionalized Primary and Secondary Amines with Aryl and Heteroaryl Halides: Two Ligands Suffice in Most CasesRecent advances in micro reaction technology.Cross-coupling in flow.Transition metal-catalyzed N-arylations of amidines and guanidines.The synthesis of Bcr-Abl inhibiting anticancer pharmaceutical agents imatinib, nilotinib and dasatinib.Accessing new chemical entities through microfluidic systems.Applications of Palladium-Catalyzed C-N Cross-Coupling Reactions.The development of a general strategy for the synthesis of tyramine-based natural products by using continuous flow techniques.A continuous flow process using a sequence of microreactors with in-line IR analysis for the preparation of N,N-diethyl-4-(3-fluorophenylpiperidin-4-ylidenemethyl)benzamide as a potent and highly selective δ-opioid receptor agonist.Heating under high-frequency inductive conditions: application to the continuous synthesis of the neurolepticum olanzapine (Zyprexa).Investigation of a lithium-halogen exchange flow process for the preparation of boronates by using a cryo-flow reactor.A machine-assisted flow synthesis of SR48692: a probe for the investigation of neurotensin receptor-1.Kinase-targeted cancer therapies: progress, challenges and future directions.On being green: can flow chemistry help?Multistep continuous-flow synthesis in medicinal chemistry: discovery and preliminary structure-activity relationships of CCR8 ligands.CHEMICAL SYNTHESIS. Going with the flow.Flow-Synthesis of Nucleosides Catalyzed by an Immobilized Purine Nucleoside Phosphorylase fromAeromonas hydrophila: Integrated Systems of Reaction Control and Product PurificationBack Pressure Regulation of Slurry-Forming Reactions in Continuous FlowA prototype device for evaporation in batch and flow chemical processesContinuous Cold without Cryogenic Consumables: Development of a Convenient Laboratory Tool for Low-Temperature Flow ProcessesContinuous stream processing: a prototype magnetic field induced flow mixerThe Evolution of Immobilized Reagents and their Application in Flow Chemistry for the Synthesis of Natural Products and Pharmaceutical CompoundsThe flow synthesis of heterocycles for natural product and medicinal chemistry applicationsA fully automated, multistep flow synthesis of 5-amino-4-cyano-1,2,3-triazolesDiastereoselective Chain-Elongation Reactions Using Microreactors for Applications in Complex Molecule AssemblyFlow synthesis of organic azides and the multistep synthesis of imines and amines using a new monolithic triphenylphosphine reagentThe Continuous-Flow Synthesis of Carboxylic Acids using CO2 in a Tube-In-Tube Gas Permeable Membrane ReactorA breakthrough method for the accurate addition of reagents in multi-step segmented flow processingThe Continuous-Flow Synthesis of Carboxylic Acids using CO2 in a Tube-In-Tube Gas Permeable Membrane ReactorEstablishing a Flow Process to Coumarin-8-Carbaldehydes as Important Synthetic ScaffoldsOrganische Chemie 2010
P2860
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P2860
description
2010 nî lūn-bûn
@nan
2010年の論文
@ja
2010年学术文章
@wuu
2010年学术文章
@zh
2010年学术文章
@zh-cn
2010年学术文章
@zh-hans
2010年学术文章
@zh-my
2010年学术文章
@zh-sg
2010年學術文章
@yue
2010年學術文章
@zh-hant
name
A flow-based synthesis of imatinib: the API of Gleevec.
@en
A flow-based synthesis of imatinib: the API of Gleevec.
@nl
type
label
A flow-based synthesis of imatinib: the API of Gleevec.
@en
A flow-based synthesis of imatinib: the API of Gleevec.
@nl
prefLabel
A flow-based synthesis of imatinib: the API of Gleevec.
@en
A flow-based synthesis of imatinib: the API of Gleevec.
@nl
P356
P1476
A flow-based synthesis of imatinib: the API of Gleevec.
@en
P2093
Mark D Hopkin
P2860
P304
P356
10.1039/C001550D
P407
P577
2010-03-05T00:00:00Z