Glucose-dependent insulinotropic polypeptide and glucagon-like peptide-1 modulate beta-cell chromatin structure.
about
Brd2 gene disruption causes "metabolically healthy" obesity: epigenetic and chromatin-based mechanisms that uncouple obesity from type 2 diabetesHormonal response to a mixed-meal challenge after reversal of gastric bypass for hypoglycemiaGlucose-dependent insulinotropic polypeptide signaling in pancreatic β-cells and adipocytesEpigenetic mechanisms in the development of type 2 diabetes.Insulin but not glucagon gene is silenced in human pancreas-derived mesenchymal stem cellsEarly-life origins of type 2 diabetes: fetal programming of the beta-cell mass.Exenatide promotes cognitive enhancement and positive brain metabolic changes in PS1-KI mice but has no effects in 3xTg-AD animals.Trichostatin A affects the secretion pathways of beta and intestinal endocrine cells.Exendin-4 induces extracellular-superoxide dismutase through histone H3 acetylation in human retinal endothelial cells.Histone deacetylase (HDAC) inhibition as a novel treatment for diabetes mellitus.Pancreatic β-cell prosurvival effects of the incretin hormones involve post-translational modification of Kv2.1 delayed rectifier channels.Adipocyte expression of the glucose-dependent insulinotropic polypeptide receptor involves gene regulation by PPARγ and histone acetylation.Incretin-stimulated interaction between β-cell Kv1.5 and Kvβ2 channel proteins involves acetylation/deacetylation by CBP/SirT1.ASF1B chaperones histone 3.3 to the β-cell cycle dance.G protein coupled-receptor signaling and reversible lysine acetylation.Menin and PRMT5 suppress GLP1 receptor transcript and PKA-mediated phosphorylation of FOXO1 and CREB.Does epigenetic dysregulation of pancreatic islets contribute to impaired insulin secretion and type 2 diabetes?
P2860
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P2860
Glucose-dependent insulinotropic polypeptide and glucagon-like peptide-1 modulate beta-cell chromatin structure.
description
2009 nî lūn-bûn
@nan
2009年の論文
@ja
2009年学术文章
@wuu
2009年学术文章
@zh
2009年学术文章
@zh-cn
2009年学术文章
@zh-hans
2009年学术文章
@zh-my
2009年学术文章
@zh-sg
2009年學術文章
@yue
2009年學術文章
@zh-hant
name
Glucose-dependent insulinotrop ...... beta-cell chromatin structure.
@en
Glucose-dependent insulinotrop ...... beta-cell chromatin structure.
@nl
type
label
Glucose-dependent insulinotrop ...... beta-cell chromatin structure.
@en
Glucose-dependent insulinotrop ...... beta-cell chromatin structure.
@nl
prefLabel
Glucose-dependent insulinotrop ...... beta-cell chromatin structure.
@en
Glucose-dependent insulinotrop ...... beta-cell chromatin structure.
@nl
P2093
P2860
P356
P1476
Glucose-dependent insulinotrop ...... beta-cell chromatin structure.
@en
P2093
Christopher H S McIntosh
Cuilan Nian
Su-Jin Kim
P2860
P304
12896-12904
P356
10.1074/JBC.M809046200
P407
P577
2009-03-11T00:00:00Z