Gold(I)-catalyzed coupling reactions for the synthesis of diverse small molecules using the build/couple/pair strategy.
about
A design strategy for drug-like polyheterocycles with privileged substructures for discovery of specific small-molecule modulators.An aldol-based build/couple/pair strategy for the synthesis of medium- and large-sized rings: discovery of macrocyclic histone deacetylase inhibitors.Creation and manipulation of common functional groups en route to a skeletally diverse chemical libraryThe rise, fall and reinvention of combinatorial chemistry.A biomimetic polyketide-inspired approach to small-molecule ligand discovery.Modular, One-Pot, Sequential Aziridine Ring Opening-S(N)Ar Strategy to 7-, 10-, and 11-Membered Benzo-Fused Sultams.Gold-catalysed reactions of diynes.A modular reaction pairing approach to the diversity-oriented synthesis of fused- and bridged-polycyclic sultams.Syntheses of α-pyrones using gold-catalyzed coupling reactions.Gold-catalyzed [2+2+1] cycloaddition of 1,6-diyne carbonates and esters with aldehydes to 4-(cyclohexa-1,3-dienyl)-1,3-dioxolanes.In situ generation of nucleophilic allenes by the gold-catalyzed rearrangement of propargylic esters for the highly diastereoselective formation of intermolecular C(sp3)-C(sp2) bonds.Relay catalytic branching cascade: a technique to access diverse molecular scaffolds.Gold-catalyzed formal 1,6-acyloxy migration leading to 3,4-disubstituted pyrrolidin-2-ones.Gold-catalyzed cycloisomerization of 1,6,8-dienyne carbonates and esters to cis-cyclohepta-4,8-diene-fused pyrrolidines.Synthesis of Skeletally Diverse Alkaloid-Like Small Molecules
P2860
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P2860
Gold(I)-catalyzed coupling reactions for the synthesis of diverse small molecules using the build/couple/pair strategy.
description
2009 nî lūn-bûn
@nan
2009年の論文
@ja
2009年学术文章
@wuu
2009年学术文章
@zh
2009年学术文章
@zh-cn
2009年学术文章
@zh-hans
2009年学术文章
@zh-my
2009年学术文章
@zh-sg
2009年學術文章
@yue
2009年學術文章
@zh-hant
name
Gold(I)-catalyzed coupling rea ...... he build/couple/pair strategy.
@en
type
label
Gold(I)-catalyzed coupling rea ...... he build/couple/pair strategy.
@en
prefLabel
Gold(I)-catalyzed coupling rea ...... he build/couple/pair strategy.
@en
P2860
P356
P1476
Gold(I)-catalyzed coupling rea ...... he build/couple/pair strategy.
@en
P2093
Stuart L Schreiber
Tuoping Luo
P2860
P304
P356
10.1021/JA900414S
P407
P577
2009-04-01T00:00:00Z