Beta2-adrenergic receptor redistribution in heart failure changes cAMP compartmentation.
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Stimulation of ICa by basal PKA activity is facilitated by caveolin-3 in cardiac ventricular myocytesCardiac cAMP: production, hydrolysis, modulation and detectionImaging alterations of cardiomyocyte cAMP microdomains in diseaseThe genetically encoded tool set for investigating cAMP: more than the sum of its partsStudying GPCR/cAMP pharmacology from the perspective of cellular structureThe scanning ion conductance microscope for cellular physiologyCaV1.2 signaling complexes in the heartSpatial control of cAMP signalling in health and diseaseMembrane domain formation-a key factor for targeted intracellular drug deliveryCompartmentalization of β-adrenergic signals in cardiomyocytesNanoscale visualization of functional adhesion/excitability nodes at the intercalated disc.Functional interaction between charged nanoparticles and cardiac tissue: a new paradigm for cardiac arrhythmia?A critical role for Telethonin in regulating t-tubule structure and function in the mammalian heartFRET measurements of intracellular cAMP concentrations and cAMP analog permeability in intact cellsPhosphoinositide 3-kinase γ protects against catecholamine-induced ventricular arrhythmia through protein kinase A-mediated regulation of distinct phosphodiesterasesA compartmentalized mathematical model of the β1-adrenergic signaling system in mouse ventricular myocytesNuclear pore rearrangements and nuclear trafficking in cardiomyocytes from rat and human failing heartsPKA catalytic subunit compartmentation regulates contractile and hypertrophic responses to β-adrenergic signalingMechanisms of cyclic AMP compartmentation revealed by computational models.Single-molecule analysis of fluorescently labeled G-protein-coupled receptors reveals complexes with distinct dynamics and organizationAxial tubule junctions control rapid calcium signaling in atriaG protein-coupled receptors in cardiac biology: old and new receptorsMicrodomain-specific localization of functional ion channels in cardiomyocytes: an emerging concept of local regulation and remodelling.T-tubule remodelling disturbs localized β2-adrenergic signalling in rat ventricular myocytes during the progression of heart failure.Caveolae create local signalling domains through their distinct protein content, lipid profile and morphologyShape and compliance of endothelial cells after shear stress in vitro or from different aortic regions: scanning ion conductance microscopy study.Correlative intravital imaging of cGMP signals and vasodilation in mice.The coordinated increased expression of biliverdin reductase and heme oxygenase-2 promotes cardiomyocyte survival: a reductase-based peptide counters β-adrenergic receptor ligand-mediated cardiac dysfunction.Increased response to β₂-adrenoreceptor stimulation augments inhibition of IKr in heart failure ventricular myocytesCardiac T-Tubule Microanatomy and Function.Decreased polycystin 2 expression alters calcium-contraction coupling and changes β-adrenergic signaling pathways.Effects of cholesterol depletion on compartmentalized cAMP responses in adult cardiac myocytes.Myocardial oxidative stress contributes to transgenic β₂-adrenoceptor activation-induced cardiomyopathy and heart failure.Palmitate diet-induced loss of cardiac caveolin-3: a novel mechanism for lipid-induced contractile dysfunction.Caveolin-3 regulates compartmentation of cardiomyocyte beta2-adrenergic receptor-mediated cAMP signaling.Dependence of cardiac transverse tubules on the BAR domain protein amphiphysin II (BIN-1)Local control of β-adrenergic stimulation: Effects on ventricular myocyte electrophysiology and Ca(2+)-transient.Formoterol and salmeterol induce a similar degree of β2-adrenoceptor tolerance in human small airways but via different mechanismsScanning ion conductance microscopy: a convergent high-resolution technology for multi-parametric analysis of living cardiovascular cellsCalpain-dependent cleavage of junctophilin-2 and T-tubule remodeling in a mouse model of reversible heart failure
P2860
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P2860
Beta2-adrenergic receptor redistribution in heart failure changes cAMP compartmentation.
description
2010 nî lūn-bûn
@nan
2010年の論文
@ja
2010年学术文章
@wuu
2010年学术文章
@zh
2010年学术文章
@zh-cn
2010年学术文章
@zh-hans
2010年学术文章
@zh-my
2010年学术文章
@zh-sg
2010年學術文章
@yue
2010年學術文章
@zh-hant
name
Beta2-adrenergic receptor redistribution in heart failure changes cAMP compartmentation.
@en
Beta2-adrenergic receptor redistribution in heart failure changes cAMP compartmentation.
@nl
type
label
Beta2-adrenergic receptor redistribution in heart failure changes cAMP compartmentation.
@en
Beta2-adrenergic receptor redistribution in heart failure changes cAMP compartmentation.
@nl
prefLabel
Beta2-adrenergic receptor redistribution in heart failure changes cAMP compartmentation.
@en
Beta2-adrenergic receptor redistribution in heart failure changes cAMP compartmentation.
@nl
P50
P356
P1433
P1476
Beta2-adrenergic receptor redistribution in heart failure changes cAMP compartmentation
@en
P2093
Alexander R Lyon
Helen Paur
P304
P356
10.1126/SCIENCE.1185988
P407
P50
P577
2010-02-25T00:00:00Z