Global DNA hypermethylation-associated cancer chemotherapy resistance and its reversion with the demethylating agent hydralazine. - Wikidata - wikimedia - TriplyDB

Global DNA hypermethylation-associated cancer chemotherapy resistance and its reversion with the demethylating agent hydralazine.

Global DNA hypermethylation-associated cancer chemotherapy resistance and its reversion with the demethylating agent hydralazine.

http://www.wikidata.org/entity/Q43150766

about

DNA methylation-independent reversion of gemcitabine resistance by hydralazine in cervical cancer cells Targeting DNA methylation for epigenetic therapy.Dual regulation of P-glycoprotein expression by trichostatin A in cancer cell lines Small-molecular modulators of cancer-associated epigenetic mechanisms.Interpreting clinical assays for histone deacetylase inhibitors.Control of prostate cancer associated with withdrawal of a supplement containing folic acid, L-methyltetrahydrofolate and vitamin B12: a case report Methylation of death-associated protein kinase is associated with cetuximab and erlotinib resistance.Highly synergistic effect of sequential treatment with epigenetic and anticancer drugs to overcome drug resistance in breast cancer cells is mediated via activation of p21 gene expression leading to G2/M cycle arrest.A Phase I Protocol of Hydralazine and Valproic Acid in Advanced, Previously Treated Solid Cancers.Epigenetic drugs as pleiotropic agents in cancer treatment: biomolecular aspects and clinical applications.Regulation of demethylation and re-expression of RASSF1A gene in gastric cancer cell lines by combined treatment of 5-Aza-CdR and NaB ERα propelled aberrant global DNA hypermethylation by activating the DNMT1 gene to enhance anticancer drug resistance in human breast cancer cells.Association between hypermethylation of DNA repetitive elements in white blood cell DNA and early-onset colorectal cancer.Epigenetic modification of Nrf2 in 5-fluorouracil-resistant colon cancer cells: involvement of TET-dependent DNA demethylation.Hydralazine-valproate: a repositioned drug combination for the epigenetic therapy of cancer.Hepatitis viruses exploitation of host DNA methyltransferases functions.Developmental DNA methyltransferase inhibitors in the treatment of gynecologic cancers.Promoter demethylation of nuclear factor-erythroid 2-related factor 2 gene in drug-resistant colon cancer cells.Enhancement of chemotherapeutic efficacy in hypermethylator breast cancer cells through targeted and pharmacologic inhibition of DNMT3b.Identification of hypermethylated genes associated with cisplatin resistance in human cancers Natural products as DNA methyltransferase inhibitors: a computer-aided discovery approach.N-Acetyltransferase 2 Genotype-Dependent N-Acetylation of Hydralazine in Human Hepatocytes.The inhibition of UBC13 expression and blockage of the DNMT1-CHFR-Aurora A pathway contribute to paclitaxel resistance in ovarian cancer.ETV7-Mediated DNAJC15 Repression Leads to Doxorubicin Resistance in Breast Cancer Cells

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Global DNA hypermethylation-associated cancer chemotherapy resistance and its reversion with the demethylating agent hydralazine.

http://www.wikidata.org/entity/Q43150766

description

2006 nî lūn-bûn

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2006年の論文

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2006年学术文章

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2006年学术文章

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2006年学术文章

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2006年学术文章

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2006年学术文章

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2006年学术文章

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2006年學術文章

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2006年學術文章

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name

Global DNA hypermethylation-as ...... methylating agent hydralazine.

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Global DNA hypermethylation-as ...... methylating agent hydralazine.

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type

label

Global DNA hypermethylation-as ...... methylating agent hydralazine.

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Global DNA hypermethylation-as ...... methylating agent hydralazine.

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Global DNA hypermethylation-as ...... methylating agent hydralazine.

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Global DNA hypermethylation-as ...... methylating agent hydralazine.

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Global DNA hypermethylation-as ...... methylating agent hydralazine.

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Alfonso Duenas-González

http://www.w3.org/2001/XMLSchema#string

Alma Chavez-Blanco

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Alma Revilla-Vazquez

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Blanca Segura-Pacheco

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Enrique Perez-Cardenas

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Lucia Taja-Chayeb

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Luis Benitez-Bribiesca

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P2860

The human DNA methyltransferases (DNMTs) 1, 3a and 3b: coordinate mRNA expression in normal tissues and overexpression in tumors

DNA methyltransferases Dnmt3a and Dnmt3b are essential for de novo methylation and mammalian development

DNMT1 binds HDAC2 and a new co-repressor, DMAP1, to form a complex at replication foci

Transcriptional repression by the methyl-CpG-binding protein MeCP2 involves a histone deacetylase complex

Dnmt2 is not required for de novo and maintenance methylation of viral DNA in embryonic stem cells

A phase I study of hydralazine to demethylate and reactivate the expression of tumor suppressor genes

Antineoplastic effects of the DNA methylation inhibitor hydralazine and the histone deacetylase inhibitor valproic acid in cancer cell lines.

Expression of DNA methyltransferases DNMT1, 3A, and 3B in normal hematopoiesis and in acute and chronic myelogenous leukemia

De novo CpG island methylation in human cancer cells

MeCP2 is a transcriptional repressor with abundant binding sites in genomic chromatin

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