Homologous and heterologous desensitization of capsaicin and mustard oil responses utilize different cellular pathways in nociceptors.
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Heat generates oxidized linoleic acid metabolites that activate TRPV1 and produce pain in rodentsThe cytochrome P450 inhibitor, ketoconazole, inhibits oxidized linoleic acid metabolite-mediated peripheral inflammatory painEffects of neurokinin-1 receptor agonism and antagonism in the rostral ventromedial medulla of rats with acute or persistent inflammatory nociceptionChemokines and the pathophysiology of neuropathic painTNFα induces co-trafficking of TRPV1/TRPA1 in VAMP1-containing vesicles to the plasmalemma via Munc18-1/syntaxin1/SNAP-25 mediated fusion.Contribution of TRPV1-TRPA1 interaction to the single channel properties of the TRPA1 channel.Tmem100 Is a Regulator of TRPA1-TRPV1 Complex and Contributes to Persistent PainTRPA1 receptors mediate environmental irritant-induced meningeal vasodilatation.4-oxo-2-nonenal (4-ONE): evidence of transient receptor potential ankyrin 1-dependent and -independent nociceptive and vasoactive responses in vivo.Transient receptor potential channel A1 and noxious cold responses in rat cutaneous nociceptorsInflammatory pain control by blocking oxidized phospholipid-mediated TRP channel activation.Co-administration of δ- and μ-opioid receptor agonists promotes peripheral opioid receptor functionPP2B/calcineurin-mediated desensitization of TRPV1 does not require AKAP150.Orofacial painChronic alteration in phosphatidylinositol 4,5-biphosphate levels regulates capsaicin and mustard oil responses.Propofol restores transient receptor potential vanilloid receptor subtype-1 sensitivity via activation of transient receptor potential ankyrin receptor subtype-1 in sensory neurons.Desensitization of transient receptor potential ankyrin 1 (TRPA1) by the TRP vanilloid 1-selective cannabinoid arachidonoyl-2 chloroethanolamineCannabinoid receptor antagonists AM251 and AM630 activate TRPA1 in sensory neurons.Propofol causes vasodilation in vivo via TRPA1 ion channels: role of nitric oxide and BKCa channelsPersistent Nociception Triggered by Nerve Growth Factor (NGF) Is Mediated by TRPV1 and Oxidative Mechanisms.Propofol restores TRPV1 sensitivity via a TRPA1-, nitric oxide synthase-dependent activation of PKCε.Cigarette smoke has sensory effects through nicotinic and TRPA1 but not TRPV1 receptors on the isolated mouse trachea and larynxProstaglandin metabolite induces inhibition of TRPA1 and channel-dependent nociception.P2X₃ and TRPV1 functionally interact and mediate sensitization of trigeminal sensory neurons.Cyclophosphamide-induced cystitis reduces ASIC channel but enhances TRPV1 receptor function in rat bladder sensory neurons.Receptor and channel heteromers as pain targets.Eugenol and carvacrol induce temporally desensitizing patterns of oral irritation and enhance innocuous warmth and noxious heat sensation on the tongue.Role of ionotropic cannabinoid receptors in peripheral antinociception and antihyperalgesiaCytokine and chemokine regulation of sensory neuron function.Targeting Pain-evoking Transient Receptor Potential Channels for the Treatment of Pain.Capsaicin-evoked iCGRP release from human dental pulp: a model system for the study of peripheral neuropeptide secretion in normal healthy tissue.Intracellular TRPA1 mediates Ca2+ release from lysosomes in dorsal root ganglion neurons.Oxidative challenges sensitize the capsaicin receptor by covalent cysteine modification.TPRV1 expression defines functionally distinct pelvic colon afferents.Nitro-oleic acid desensitizes TRPA1 and TRPV1 agonist responses in adult rat DRG neurons.Tachykinins and their receptors: contributions to physiological control and the mechanisms of disease.Furanocoumarins are a novel class of modulators for the transient receptor potential vanilloid type 1 (TRPV1) channel.Properties and therapeutic potential of transient receptor potential channels with putative roles in adversity: focus on TRPC5, TRPM2 and TRPA1.The functions of TRPA1 and TRPV1: moving away from sensory nervesThe role of flavor and fragrance chemicals in TRPA1 (transient receptor potential cation channel, member A1) activity associated with allergies.
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P2860
Homologous and heterologous desensitization of capsaicin and mustard oil responses utilize different cellular pathways in nociceptors.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年学术文章
@wuu
2007年学术文章
@zh
2007年学术文章
@zh-cn
2007年学术文章
@zh-hans
2007年学术文章
@zh-my
2007年学术文章
@zh-sg
2007年學術文章
@yue
2007年學術文章
@zh-hant
name
Homologous and heterologous de ...... lular pathways in nociceptors.
@en
Homologous and heterologous de ...... lular pathways in nociceptors.
@nl
type
label
Homologous and heterologous de ...... lular pathways in nociceptors.
@en
Homologous and heterologous de ...... lular pathways in nociceptors.
@nl
prefLabel
Homologous and heterologous de ...... lular pathways in nociceptors.
@en
Homologous and heterologous de ...... lular pathways in nociceptors.
@nl
P2093
P2860
P1433
P1476
Homologous and heterologous de ...... lular pathways in nociceptors.
@en
P2093
Amol M Patwardhan
Armen N Akopian
Kenneth M Hargreaves
Nikita B Ruparel
P2860
P304
P356
10.1016/J.PAIN.2007.06.005
P407
P577
2007-06-27T00:00:00Z