Islet transplantation in patients with autoimmune diabetes induces homeostatic cytokines that expand autoreactive memory T cells.
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Targeting Homeostatic T Cell Proliferation to Control Beta-Cell AutoimmunityEvolution of β-Cell Replacement Therapy in Diabetes Mellitus: Islet Cell TransplantationRecurrence of autoimmunity following pancreas transplantation.Recurrence of type 1 diabetes after simultaneous pancreas-kidney transplantation, despite immunosuppression, is associated with autoantibodies and pathogenic autoreactive CD4 T-cells.Altered regulatory T cell homeostasis in patients with CD4+ lymphopenia following allogeneic hematopoietic stem cell transplantation.Immune tolerance induction by integrating innate and adaptive immune regulators.Simultaneous detection of circulating autoreactive CD8+ T-cells specific for different islet cell-associated epitopes using combinatorial MHC multimers.Differential mechanisms of memory CD8 T cell maintenance by individual myeloid cell types.A novel clinically relevant strategy to abrogate autoimmunity and regulate alloimmunity in NOD mice.Mesenchymal stem-cell immunosuppressive capabilities: therapeutic implications in islet transplantationTIM4 Regulates the Anti-Islet Th2 Alloimmune ResponseProlonged insulin independence after islet allotransplants in recipients with type 1 diabetes.Premature CD4+ T cell aging and its contribution to lymphopenia-induced proliferation of memory cells in autoimmune-prone non-obese diabetic miceIL-21 is an antitolerogenic cytokine of the late-phase alloimmune response.Combination of an Antigen-Specific Therapy and an Immunomodulatory Treatment to Simultaneous Block Recurrent Autoimmunity and Alloreactivity in Non-Obese Diabetic Mice.Antigen-specific therapeutic approaches in Type 1 diabetesThiobenzothiazole-modified Hydrocortisones Display Anti-inflammatory Activity with Reduced Impact on Islet β-Cell Function.Tolerance-inducing strategies in islet transplantationPotent induction immunotherapy promotes long-term insulin independence after islet transplantation in type 1 diabetesCXCR1/2 inhibition enhances pancreatic islet survival after transplantation.CD18 is required for optimal lymphopenia-induced proliferation of mouse T cells.Immunosuppression in islet transplantationImmune rejection after pancreatic islet cell transplantation: in vivo dual contrast-enhanced MR imaging in a mouse model.Five-year follow-up of patients with type 1 diabetes transplanted with allogeneic islets: the UIC experienceSuppression of IL-7-dependent Effector T-cell Expansion by Multipotent Adult Progenitor Cells and PGE2.Targeting purinergic receptors in islet transplantation.Effect of the purinergic inhibitor oxidized ATP in a model of islet allograft rejection.Concentration and activity of the soluble form of the interleukin-7 receptor α in type 1 diabetes identifies an interplay between hyperglycemia and immune function.Can we learn from viruses how to prevent type 1 diabetes?: the role of viral infections in the pathogenesis of type 1 diabetes and the development of novel combination therapies.Multifunctional magnetic nanocarriers for image-tagged SiRNA delivery to intact pancreatic isletsChanges in autoreactive T cell avidity during type 1 diabetes development.Differences in baseline lymphocyte counts and autoreactivity are associated with differences in outcome of islet cell transplantation in type 1 diabetic patients.Current advances and travails in islet transplantation.Translating transplantation tolerance in the clinic: where are we, where do we go?Innate immunity and heat shock response in islet transplantation.Detection of GAD65 autoreactive T-cells by HLA class I tetramers in type 1 diabetic patients.Autologous and Allogenous Antibodies in Lung and Islet Cell Transplantation.Pancreatic islet transplantation.Homeostatic T cell proliferation after islet transplantation.Monitoring Inflammation, Humoral and Cell-mediated Immunity in Pancreas and Islet Transplants.
P2860
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P2860
Islet transplantation in patients with autoimmune diabetes induces homeostatic cytokines that expand autoreactive memory T cells.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年学术文章
@wuu
2008年学术文章
@zh
2008年学术文章
@zh-cn
2008年学术文章
@zh-hans
2008年学术文章
@zh-my
2008年学术文章
@zh-sg
2008年學術文章
@yue
2008年學術文章
@zh-hant
name
Islet transplantation in patie ...... d autoreactive memory T cells.
@en
Islet transplantation in patie ...... d autoreactive memory T cells.
@nl
type
label
Islet transplantation in patie ...... d autoreactive memory T cells.
@en
Islet transplantation in patie ...... d autoreactive memory T cells.
@nl
prefLabel
Islet transplantation in patie ...... d autoreactive memory T cells.
@en
Islet transplantation in patie ...... d autoreactive memory T cells.
@nl
P2093
P2860
P50
P356
P1476
Islet transplantation in patie ...... d autoreactive memory T cells.
@en
P2093
Antonio Secchi
Federico Bertuzzi
Francesca De Taddeo
Miriam Scirpoli
Nadia Ghidoli
Paola Maffi
P2860
P304
P356
10.1172/JCI35197
P407
P577
2008-05-01T00:00:00Z