about
Intracellular CXCR4⁺ cell targeting with T22-empowered protein-only nanoparticles.Microbial factories for recombinant pharmaceuticalsEngineered biological entities for drug delivery and gene therapy protein nanoparticles.Internalization and kinetics of nuclear migration of protein-only, arginine-rich nanoparticles.Dual Actions of Apolipoprotein A-I on Glucose-Stimulated Insulin Secretion and Insulin-Independent Peripheral Tissue Glucose Uptake Lead to Increased Heart and Skeletal Muscle Glucose Disposal.Molecular crowding impacts the structure of apolipoprotein A-I with potential implications on in vivo metabolism and function.Sheltering DNA in self-organizing, protein-only nano-shells as artificial viruses for gene delivery.ApoA-I Milano stimulates lipolysis in adipose cells independently of cAMP/PKA activation.Protein nanodisk assembling and intracellular trafficking powered by an arginine-rich (R9) peptide.Nanoparticulate architecture of protein-based artificial viruses is supported by protein-DNA interactions.Protein aggregation and soluble aggregate formation screened by a fast microdialysis assay.RGD-based cell ligands for cell-targeted drug delivery act as potent trophic factorsNon-amyloidogenic peptide tags for the regulatable self-assembling of protein-only nanoparticlesSite-specific glycations of apolipoprotein A-I lead to differentiated functional effects on lipid-binding and on glucose metabolismApoAI-derived peptide increases glucose tolerance and prevents formation of atherosclerosis in mice
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P50
description
researcher
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wetenschapper
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հետազոտող
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name
Joan Domingo-Espin
@ast
Joan Domingo-Espin
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Joan Domingo-Espin
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Joan Domingo-Espin
@nl
Joan Domingo-Espin
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type
label
Joan Domingo-Espin
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Joan Domingo-Espin
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Joan Domingo-Espin
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Joan Domingo-Espin
@nl
Joan Domingo-Espin
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Joan Domingo-Espin
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Joan Domingo-Espin
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Joan Domingo-Espin
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Joan Domingo-Espin
@nl
Joan Domingo-Espin
@sl
P106
P31
P496
0000-0001-8149-0803