Effects of A-317491, a novel and selective P2X3/P2X2/3 receptor antagonist, on neuropathic, inflammatory and chemogenic nociception following intrathecal and intraplantar administration. - Wikidata - wikimedia - TriplyDB

Effects of A-317491, a novel and selective P2X3/P2X2/3 receptor antagonist, on neuropathic, inflammatory and chemogenic nociception following intrathecal and intraplantar administration.

Effects of A-317491, a novel and selective P2X3/P2X2/3 receptor antagonist, on neuropathic, inflammatory and chemogenic nociception following intrathecal and intraplantar administration.

http://www.wikidata.org/entity/Q43162171

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A P2X receptor-mediated nociceptive afferent pathway to lamina I of the spinal cord Nociceptive transmission and modulation via P2X receptors in central pain syndrome Potential for developing purinergic drugs for gastrointestinal diseases P2X2 knockout mice and P2X2/P2X3 double knockout mice reveal a role for the P2X2 receptor subunit in mediating multiple sensory effects of ATP In pursuit of P2X3 antagonists: novel therapeutics for chronic pain and afferent sensitization.The h-P2X3 glycoprotein receptor as an example of integrating bioinformatics and structural research.Endosome-mediated retrograde axonal transport of P2X3 receptor signals in primary sensory neurons Nav1.9 channel contributes to mechanical and heat pain hypersensitivity induced by subacute and chronic inflammation.Sensitization of cutaneous neuronal purinergic receptors contributes to endothelin-1-induced mechanical hypersensitivity Neuromodulation by extracellular ATP and P2X receptors in the CNS.Endogenous purinergic control of bladder activity via presynaptic P2X3 and P2X2/3 receptors in the spinal cord.P2X receptors in sensory neurons co-cultured with cancer cells exhibit a decrease in opioid sensitivity.P2X receptors: New players in cancer pain.Air-stimulated ATP release from keratinocytes occurs through connexin hemichannels.Estrogen modulation of peripheral pain signal transduction: involvement of P2X(3) receptors.Mechanisms underlying purinergic P2X3 receptor-mediated mechanical allodynia induced in diabetic rats Sensitization of P2X3 receptors by cystathionine β-synthetase mediates persistent pain hypersensitivity in a rat model of lumbar disc herniation.Purinoceptors as therapeutic targets for lower urinary tract dysfunction.Translocation of neuronal nitric oxide synthase to the plasma membrane by ATP is mediated by P2X and P2Y receptors.Localization of P2X2 and P2X3 receptors in rat trigeminal ganglion neurons.Functional genomics to new drug targets.Prostaglandin E2 potentiation of P2X3 receptor mediated currents in dorsal root ganglion neurons New targets for neuropathic pain therapeutics.Differential expression of ATP-gated P2X receptors in DRG between chronic neuropathic pain and visceralgia rat models.RNA interference in pain research.Purinergic receptors as potential therapeutic targets in Alzheimer's disease.Aromatase inhibitors augment nociceptive behaviors in rats and enhance the excitability of sensory neurons.Modulation of P2X3 and P2X2/3 Receptors by Monoclonal Antibodies Rho/ROCK acts downstream of lysophosphatidic acid receptor 1 in modulating P2X3 receptor-mediated bone cancer pain in rats.P2X receptor-mediated purinergic sensory pathways to the spinal cord dorsal horn.P2 receptors and chronic pain Sustained stimulation of vasopressin and oxytocin release by ATP and phenylephrine requires recruitment of desensitization-resistant P2X purinergic receptors.P2X receptor antagonists for pain management: examination of binding and physicochemical properties.Modulation of neuropathic-pain-related behaviour by the spinal endocannabinoid/endovanilloid system.P2X3 and P2X2/3 receptor antagonists.Calcium-permeable ion channels in pain signaling.Investigation into the role of P2X(3)/P2X(2/3) receptors in neuropathic pain following chronic constriction injury in the rat: an electrophysiological study P2X3 antagonists: novel therapeutics for afferent sensitization and chronic pain.siRNA relieves chronic neuropathic pain P2X7 receptor blockade reverses purinergic facilitation of neck muscle nociception in mice.

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P2860

Effects of A-317491, a novel and selective P2X3/P2X2/3 receptor antagonist, on neuropathic, inflammatory and chemogenic nociception following intrathecal and intraplantar administration.

http://www.wikidata.org/entity/Q43162171

description

2003 nî lūn-bûn

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2003年学术文章

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2003年学术文章

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Effects of A-317491, a novel a ...... d intraplantar administration.

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Effects of A-317491, a novel a ...... d intraplantar administration.

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Effects of A-317491, a novel a ...... d intraplantar administration.

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Effects of A-317491, a novel a ...... d intraplantar administration.

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Effects of A-317491, a novel a ...... d intraplantar administration.

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Effects of A-317491, a novel a ...... d intraplantar administration.

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British Journal of Pharmacology

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Effects of A-317491, a novel a ...... d intraplantar administration.

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Carol T Wismer

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Chang Z Zhu

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Chih-Hung Lee

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Connie R Faltynek

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Joseph Mikusa

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Katharine L Chu

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Michael F Jarvis

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P2860

P2X4 receptors induced in spinal microglia gate tactile allodynia after nerve injury

Characterization of the UDP-glucose receptor (re-named here the P2Y14 receptor) adds diversity to the P2Y receptor family

Receptors for purines and pyrimidines

Cloning OF P2X5 and P2X6 receptors and the distribution and properties of an extended family of ATP-gated ion channels

Evidence for the involvement of spinal endogenous ATP and P2X receptors in nociceptive responses caused by formalin and capsaicin in mice

Selective activation of nociceptors by P2X receptor agonists in normal and inflamed rat skin

Modulation of BzATP and formalin induced nociception: attenuation by the P2X receptor antagonist, TNP-ATP and enhancement by the P2X(3) allosteric modulator, cibacron blue

Warm-coding deficits and aberrant inflammatory pain in mice lacking P2X3 receptors

Urinary bladder hyporeflexia and reduced pain-related behaviour in P2X3-deficient mice

A new and sensitive method for measuring thermal nociception in cutaneous hyperalgesia

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1381-1388

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10.1038/SJ.BJP.0705574

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