RNA aptamers to initiation factor 4A helicase hinder cap-dependent translation by blocking ATP hydrolysis.
about
Stimulation of mammalian translation initiation factor eIF4A activity by a small molecule inhibitor of eukaryotic translation.Translational control by a small RNA: dendritic BC1 RNA targets the eukaryotic initiation factor 4A helicase mechanismNMR structures of double loops of an RNA aptamer against mammalian initiation factor 4ATechniques for following the movement of single RNAs in living cellsAptamer-based molecular imagingConformational plasticity of RNA for target recognition as revealed by the 2.15 A crystal structure of a human IgG-aptamer complexEukaryotic initiation factor 4a3 is a selenium-regulated RNA-binding protein that selectively inhibits selenocysteine incorporationIdentification of a signature motif for the eIF4a3-SECIS interactionRNA plasticity and selectivity applicable to therapeutics and novel biosensor developmentSpatiotemporal patterns and transcription kinetics of induced RNA in single bacterial cells.Selective pharmacological targeting of a DEAD box RNA helicase.Therapeutic potential of anti-interleukin-17A aptamer: suppression of interleukin-17A signaling and attenuation of autoimmunity in two mouse models.RNA helicases in infection and disease.eIF4G stimulates the activity of the DEAD box protein eIF4A by a conformational guidance mechanism.RNA aptamers to mammalian initiation factor 4G inhibit cap-dependent translation by blocking the formation of initiation factor complexes.Aptamer-based Sandwich Assay and its Clinical Outlooks for Detecting Lipocalin-2 in Hepatocellular Carcinoma (HCC).RNA imaging in living cells - methods and applications.Cotinine-conjugated aptamer/anti-cotinine antibody complexes as a novel affinity unit for use in biological assays.Inhibition of midkine alleviates experimental autoimmune encephalomyelitis through the expansion of regulatory T cell population.The DEAD-box helicase eIF4A: paradigm or the odd one out?Structural and molecular basis for hyperspecificity of RNA aptamer to human immunoglobulin GThe Runt domain of AML1 (RUNX1) binds a sequence-conserved RNA motif that mimics a DNA element.General RNA-binding proteins have a function in poly(A)-binding protein-dependent translationAnalysis of RNA localization and metabolism in single live bacterial cells: achievements and challenges.Two stems with different characteristics and an internal loop in an RNA aptamer contribute to spermine-binding.Identification of an RNA aptamer binding hTERT-derived peptide and inhibiting telomerase activity in MCF7 cells.RNA visualization in live bacterial cells using fluorescent protein complementation.Solution structure of a DNA mimicking motif of an RNA aptamer against transcription factor AML1 Runt domain.Developing anti-neoplastic biotherapeutics against eIF4F.RNA aptamers selected against the receptor activator of NF-kappaB acquire general affinity to proteins of the tumor necrosis factor receptor family.High affinity RNA for mammalian initiation factor 4E interferes with mRNA-cap binding and inhibits translationCrystallization and preliminary X-ray diffraction studies of an RNA aptamer in complex with the human IgG Fc fragment.Probe design for the effective fluorescence imaging of intracellular RNA.Targeting RNA helicases in cancer: The translation trap.
P2860
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P2860
RNA aptamers to initiation factor 4A helicase hinder cap-dependent translation by blocking ATP hydrolysis.
description
2003 nî lūn-bûn
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name
RNA aptamers to initiation fac ...... on by blocking ATP hydrolysis.
@en
RNA aptamers to initiation fac ...... on by blocking ATP hydrolysis.
@nl
type
label
RNA aptamers to initiation fac ...... on by blocking ATP hydrolysis.
@en
RNA aptamers to initiation fac ...... on by blocking ATP hydrolysis.
@nl
prefLabel
RNA aptamers to initiation fac ...... on by blocking ATP hydrolysis.
@en
RNA aptamers to initiation fac ...... on by blocking ATP hydrolysis.
@nl
P2093
P2860
P356
P1433
P1476
RNA aptamers to initiation fac ...... on by blocking ATP hydrolysis.
@en
P2093
Akihiro Oguro
Takashi Ohtsu
Yoshikazu Nakamura
Yuri V Svitkin
P2860
P304
P356
10.1261/RNA.2161303
P407
P577
2003-04-01T00:00:00Z