In vitro activation of the transcription factor gamma interferon activation factor by gamma interferon: evidence for a tyrosine phosphatase/kinase signaling cascade.
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Vaccinia virus blocks gamma interferon signal transduction: viral VH1 phosphatase reverses Stat1 activationLigand-induced IFN gamma receptor tyrosine phosphorylation couples the receptor to its signal transduction system (p91)Shp-2 tyrosine phosphatase functions as a negative regulator of the interferon-stimulated Jak/STAT pathwayDifferential regulation of the alpha/beta interferon-stimulated Jak/Stat pathway by the SH2 domain-containing tyrosine phosphatase SHPTP1Growth hormone and erythropoietin differentially activate DNA-binding proteins by tyrosine phosphorylation.Prolactin activates the interferon-regulated p91 transcription factor and the Jak2 kinase by tyrosine phosphorylation.Human cancer cell lines express a negative transcriptional regulator of the interferon regulatory factor family of DNA binding proteins.A nuclear tyrosine phosphatase downregulates interferon-induced gene expression.Leukemia inhibitory factor (LIF) stimulates proopiomelanocortin (POMC) expression in a corticotroph cell line. Role of STAT pathway.Protein-tyrosine phosphatase inhibitors block tumor necrosis factor-dependent activation of the nuclear transcription factor NF-kappa B.The mammary factor MPBF is a prolactin-induced transcriptional regulator which binds to STAT factor recognition sites.The interleukin-6-activated acute-phase response factor is antigenically and functionally related to members of the signal transducer and activator of transcription (STAT) family.The signalling pathways of interleukin-6 and gamma interferon converge by the activation of different transcription factors which bind to common responsive DNA elements.A factor induced by differentiation signals in cells of the macrophage lineage binds to the gamma interferon activation site.The SH2 domain-containing tyrosine phosphatase PTP1D is required for interferon alpha/beta-induced gene expression.Inhibition of alpha interferon but not gamma interferon signal transduction by phorbol esters is mediated by a tyrosine phosphatase.Enhancement of antiproliferative activity of gamma interferon by the specific inhibition of tyrosine dephosphorylation of Stat1.Induction of early response genes by interferons, interleukins, and growth factors by the tyrosine phosphorylation of latent transcription factors. Implications for chronic inflammatory diseases.Interferon response pathways--a paradigm for cytokine signalling?Mapping of the cytoplasmic domain of the human growth hormone receptor required for the activation of Jak2 and Stat proteins.Ligand-dependent and -independent activation of the transcription factor gamma RF-1 in a cell-free system.The response of gamma interferon activation factor is under developmental control in cells of the macrophage lineage.In vitro activation of a transcription factor by gamma interferon requires a membrane-associated tyrosine kinase and is mimicked by vanadate.Mutant cell lines unresponsive to alpha/beta and gamma interferon are defective in tyrosine phosphorylation of ISGF-3 alpha componentsClass II transactivator (CIITA) is sufficient for the inducible expression of major histocompatibility complex class II genes.Regulation of Interferon-α Responsiveness by the Duration of Janus Kinase Activity
P2860
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P2860
In vitro activation of the transcription factor gamma interferon activation factor by gamma interferon: evidence for a tyrosine phosphatase/kinase signaling cascade.
description
1993 nî lūn-bûn
@nan
1993年の論文
@ja
1993年学术文章
@wuu
1993年学术文章
@zh
1993年学术文章
@zh-cn
1993年学术文章
@zh-hans
1993年学术文章
@zh-my
1993年学术文章
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1993年學術文章
@yue
1993年學術文章
@zh-hant
name
In vitro activation of the tra ...... tase/kinase signaling cascade.
@en
In vitro activation of the tra ...... tase/kinase signaling cascade.
@nl
type
label
In vitro activation of the tra ...... tase/kinase signaling cascade.
@en
In vitro activation of the tra ...... tase/kinase signaling cascade.
@nl
prefLabel
In vitro activation of the tra ...... tase/kinase signaling cascade.
@en
In vitro activation of the tra ...... tase/kinase signaling cascade.
@nl
P2093
P2860
P356
P1476
In vitro activation of the tra ...... tase/kinase signaling cascade.
@en
P2093
P2860
P304
P356
10.1128/MCB.13.3.1634
P407
P577
1993-03-01T00:00:00Z