Functional analysis of the human adenosine deaminase gene thymic regulatory region and its ability to generate position-independent transgene expression.
about
Genomic structure and chromosomal localization of the human deoxycytidine kinase geneLocus control regionsConservation of sequence and structure flanking the mouse and human beta-globin loci: the beta-globin genes are embedded within an array of odorant receptor genesGene therapy: light is finally in the tunnelA new element within the T-cell receptor alpha locus required for tissue-specific locus control region activityLarge-scale comparative sequence analysis of the human and murine Bruton's tyrosine kinase loci reveals conserved regulatory domains.The human vitamin D-binding protein gene contains locus control determinants sufficient for autonomous activation in hepatic chromatinAn enhancer LEF-1/TCF-1 site is essential for insertion site-independent transgene expression in thymusPosition independent expression and developmental regulation is directed by the beta myosin heavy chain gene's 5' upstream region in transgenic mice.Sp1 is essential for both enhancer-mediated and basal activation of the TATA-less human adenosine deaminase promoter.The 5' flanking region of the rat LAP (C/EBP beta) gene can direct high-level, position-independent, copy number-dependent expression in multiple tissues in transgenic mice.Detection and visualization of compositionally similar cis-regulatory element clusters in orthologous and coordinately controlled genes.Analysis of muscle creatine kinase gene regulatory elements in skeletal and cardiac muscles of transgenic mice.Dissecting a locus control region: facilitation of enhancer function by extended enhancer-flanking sequences.Winner of the Theodore E. Woodward Award: c-Myb and the coordinate regulation of thymic genes.Sequences containing the second-intron enhancer are essential for transcription of the human apolipoprotein B gene in the livers of transgenic miceFast-muscle-specific expression of human aldolase A transgenesTranscriptional insulation of the human keratin 18 gene in transgenic miceAlu sequence involvement in transcriptional insulation of the keratin 18 gene in transgenic miceIdentification and characterization of an Alu-containing, T-cell-specific enhancer located in the last intron of the human CD8 alpha gene.An intron 1 regulatory region from the murine adenosine deaminase gene can activate heterologous promoters for ubiquitous expression in transgenic mice.A central role for a single c-Myb binding site in a thymic locus control region.Analysis of a 70 kb segment of DNA containing the human zeta and alpha-globin genes linked to their regulatory element (HS-40) in transgenic mice.Dissection of the locus control function located on the chicken lysozyme gene domain in transgenic mice.A regulatory element within a coding exon modulates keratin 18 gene expression in transgenic mice.Disruption of the adenosine deaminase (ADA) gene using a dicistronic promoterless construct: production of an ADA-deficient homozygote ES cell line.Specific combinations of human serum albumin introns direct high level expression of albumin in transfected COS cells and in the milk of transgenic mice.Double-stranded phosphorothioate oligonucleotide modulation of gene expression.Regulation of T cell receptor delta gene rearrangement by CBF/PEBP2.The upstream enhancer is necessary and sufficient for the expression of the pre-T cell receptor alpha gene in immature T lymphocytes.High-level activation by a duodenum-specific enhancer requires functional GATA binding sites.Regulation of forestomach-specific expression of the murine adenosine deaminase gene.Accelerated transcription of PRPS1 in X-linked overactivity of normal human phosphoribosylpyrophosphate synthetase.Position-independent, high-level, and correct regional expression of the rat aldolase C gene in the central nervous system of transgenic mice.Temporal regulation of enhancer function in intestinal epithelium: a role for Onecut factors.A duodenum-specific enhancer regulates expression along three axes in the small intestine.Diverse developing mouse lineages exhibit high-level c-Myb expression in immature cells and loss of expression upon differentiation.Regulation of duodenal specific expression of the human adenosine deaminase gene.Developmental expression of H-2K major histocompatibility complex class I transgenes requires the presence of proximal introns.
P2860
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P2860
Functional analysis of the human adenosine deaminase gene thymic regulatory region and its ability to generate position-independent transgene expression.
description
1992 nî lūn-bûn
@nan
1992年の論文
@ja
1992年学术文章
@wuu
1992年学术文章
@zh
1992年学术文章
@zh-cn
1992年学术文章
@zh-hans
1992年学术文章
@zh-my
1992年学术文章
@zh-sg
1992年學術文章
@yue
1992年學術文章
@zh-hant
name
Functional analysis of the hum ...... ependent transgene expression.
@en
Functional analysis of the hum ...... ependent transgene expression.
@nl
type
label
Functional analysis of the hum ...... ependent transgene expression.
@en
Functional analysis of the hum ...... ependent transgene expression.
@nl
prefLabel
Functional analysis of the hum ...... ependent transgene expression.
@en
Functional analysis of the hum ...... ependent transgene expression.
@nl
P2093
P2860
P356
P1476
Functional analysis of the hum ...... ependent transgene expression.
@en
P2093
B J Aronow
D A Wiginton
J J Hutton
M R Dusing
R N Silbiger
S S Potter
P2860
P304
P356
10.1128/MCB.12.9.4170
P407
P577
1992-09-01T00:00:00Z