about
Angiopoietin-like 4 is a proangiogenic factor produced during ischemia and in conventional renal cell carcinomaSuccinate dehydrogenase deficiency in humanThe R22X mutation of the SDHD gene in hereditary paraganglioma abolishes the enzymatic activity of complex II in the mitochondrial respiratory chain and activates the hypoxia pathwayHIF2 alpha reduces growth rate but promotes angiogenesis in a mouse model of neuroblastomaThe Warburg effect is genetically determined in inherited pheochromocytomasRapid determination of tricarboxylic acid cycle enzyme activities in biological samples.Vascular endothelial growth factor-A is associated with chronic mountain sickness in the Andean population.Mitochondrial Deficiencies in the Predisposition to ParagangliomaSDHA is a tumor suppressor gene causing paraganglioma.Multi-omics analysis defines core genomic alterations in pheochromocytomas and paragangliomas.Vascular pattern analysis for the prediction of clinical behaviour in pheochromocytomas and paragangliomas.Angiogenesis and vascular architecture in pheochromocytomas: distinctive traits in malignant tumors.Hereditary paraganglioma/pheochromocytoma and inherited succinate dehydrogenase deficiency.Loss of succinate dehydrogenase activity results in dependency on pyruvate carboxylation for cellular anabolism.An immunohistochemical procedure to detect patients with paraganglioma and phaeochromocytoma with germline SDHB, SDHC, or SDHD gene mutations: a retrospective and prospective analysis.Tricarboxylic acid cycle dysfunction as a cause of human diseases and tumor formation.Deciphering the molecular basis of invasiveness in Sdhb-deficient cells.A MEN1 syndrome with a paraganglioma.A decade (2001-2010) of genetic testing for pheochromocytoma and paraganglioma.The genetics of paragangliomas.Unsuspected task for an old team: succinate, fumarate and other Krebs cycle acids in metabolic remodeling.Oncometabolites-driven tumorigenesis: From genetics to targeted therapy.Paraganglioma and phaeochromocytoma: from genetics to personalized medicine.Rethinking pheochromocytomas and paragangliomas from a genomic perspective.From Nf1 to Sdhb knockout: Successes and failures in the quest for animal models of pheochromocytoma.Risk assessment of maternally inherited SDHD paraganglioma and phaeochromocytoma.Establishment of a mouse xenograft model of metastatic adrenocortical carcinoma.Functional and in silico assessment of MAX variants of unknown significance.DNA Methylation Profiling in Pheochromocytoma and Paraganglioma Reveals Diagnostic and Prognostic Markers.Role of MSK1 in the signaling pathway leading to VEGF-mediated PAF synthesis in endothelial cells.Functional consequences of a SDHB gene mutation in an apparently sporadic pheochromocytoma.Mosaicism in HIF2A-related polycythemia-paraganglioma syndrome.Mutations in the SDHB gene are associated with extra-adrenal and/or malignant phaeochromocytomas.Pheochromocytomas: the (pseudo)-hypoxia hypothesis.Role of the renin-angiotensin system in primitive erythropoiesis in the chick embryo.Angiopoietins can directly activate endothelial cells and neutrophils to promote proinflammatory responses.[Achievements of the COMETE program in the genetics of pheochromocytoma].Recent advances in the genetics of phaeochromocytoma and functional paraganglioma.Mitochondrial succinate is instrumental for HIF1alpha nuclear translocation in SDHA-mutant fibroblasts under normoxic conditions.Germline mutations in FH confer predisposition to malignant pheochromocytomas and paragangliomas.
P50
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P50
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Judith Favier
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