The specificity of cross-reactivity: promiscuous antibody binding involves specific hydrogen bonds rather than nonspecific hydrophobic stickiness.
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Antibody promiscuity: Understanding the paradigm shift in antigen recognitionHydrophobicity and charge shape cellular metabolite concentrationsHow much can a T-cell antigen receptor adapt to structurally distinct antigenic peptides?Contribution of Asparagine Residues to the Stabilization of a Proteinaceous Antigen-Antibody Complex, HyHEL-10-Hen Egg White LysozymeSubstrate Deconstruction and the Nonadditivity of Enzyme RecognitionBeauty is in the eye of the beholder: proteins can recognize binding sites of homologous proteins in more than one wayAnalogies between digital radio and chemical orthogonality as a method for enhanced analysis of molecular recognition events.Dynamic New World: Refining Our View of Protein Structure, Function and EvolutionStructure and kinetics of a transient antibody binding intermediate reveal a kinetic discrimination mechanism in antigen recognition.Peptide-conjugation induced conformational changes in human IgG1 observed by optimized negative-staining and individual-particle electron tomography.Cross-reactivity and conformational multiplicity of an anti-polycyclic aromatic hydrocarbon mAbAntibody binding loop insertions as diversity elementsBinding induced conformational changes of proteins correlate with their intrinsic fluctuations: a case study of antibodies.Exploring functional roles of multibinding protein interfaces.Immunoprevalence to Six Waterborne Pathogens in Beachgoers at Boquerón Beach, Puerto Rico: Application of a Microsphere-Based Salivary Antibody Multiplex Immunoassay.Expanding the proteome: disordered and alternatively folded proteins.Synthetic allergen design reveals the significance of moderate affinity epitopes in mast cell degranulation.A targeted quantitative proteomics strategy for global kinome profiling of cancer cells and tissues.Mechanism of the antigen-independent cytokinergic SPE-7 IgE activation of human mast cells in vitro.Highly specific off-target binding identified and eliminated during the humanization of an antibody against FGF receptor 4.Defining the complementarities between antibodies and haptens to refine our understanding and aid the prediction of a successful binding interaction.Immunopotentiating properties of a multispecific α-anti-idiotype antibody.Cytokinergic IgE Action in Mast Cell Activation.Proteomics-on-a-chip: the challenge to couple lab-on-a-chip unit operations.Computer-aided antibody design.Specificity in molecular design: a physical framework for probing the determinants of binding specificity and promiscuity in a biological environment.Interrogation of sphingosine-1-phosphate receptor 2 function in vivo reveals a prominent role in the recovery from IgE and IgG-mediated anaphylaxis with minimal effect on its onsetNon-canonical binding of an antibody resembling a naïve B cell receptor immunoglobulin to hepatitis B virus capsids.Regulation of the mast cell response to the type 1 Fc epsilon receptor.Ligase-4 Deficiency Causes Distinctive Immune Abnormalities in Asymptomatic Individuals.Directed evolution of streptavidin variants using in vitro compartmentalization.Molecular Mechanism and Energy Basis of Conformational Diversity of Antibody SPE7 Revealed by Molecular Dynamics Simulation and Principal Component AnalysisInteraction of C1q with IgG1, C-reactive protein and pentraxin 3: mutational studies using recombinant globular head modules of human C1q A, B, and C chainsInhibition of weak-affinity epitope-IgE interactions prevents mast cell degranulation.Polyreactive antibodies in adaptive immune responses to viruses.Antibodies for immunolabeling by light and electron microscopy: not for the faint hearted.Promiscuous antibodies characterised by their physico-chemical properties: From sequence to structure and back.Design of a heterotetravalent synthetic allergen that reflects epitope heterogeneity and IgE antibody variability to study mast cell degranulationThe promise of the anti-idiotype concept.Protein promiscuity: drug resistance and native functions--HIV-1 case.
P2860
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P2860
The specificity of cross-reactivity: promiscuous antibody binding involves specific hydrogen bonds rather than nonspecific hydrophobic stickiness.
description
2003 nî lūn-bûn
@nan
2003年の論文
@ja
2003年学术文章
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2003年学术文章
@zh
2003年学术文章
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2003年学术文章
@zh-hans
2003年学术文章
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2003年学术文章
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2003年學術文章
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name
The specificity of cross-react ...... ecific hydrophobic stickiness.
@en
The specificity of cross-react ...... ecific hydrophobic stickiness.
@nl
type
label
The specificity of cross-react ...... ecific hydrophobic stickiness.
@en
The specificity of cross-react ...... ecific hydrophobic stickiness.
@nl
prefLabel
The specificity of cross-react ...... ecific hydrophobic stickiness.
@en
The specificity of cross-react ...... ecific hydrophobic stickiness.
@nl
P2860
P921
P356
P1433
P1476
The specificity of cross-react ...... ecific hydrophobic stickiness.
@en
P2093
Dan S Tawfik
Leo C James
P2860
P304
P356
10.1110/PS.03172703
P577
2003-10-01T00:00:00Z