Novel 3-arylideneindolin-2-ones as inhibitors of NAD+ -dependent histone deacetylases (sirtuins).
about
Specific CLK Inhibitors from a Novel Chemotype for Regulation of Alternative SplicingRejuvenating sirtuins: the rise of a new family of cancer drug targetsDesign of a novel nucleoside analog as potent inhibitor of the NAD dependent deacetylase, SIRT2Metabolism as a key to histone deacetylase inhibition.3-(N-arylsulfamoyl)benzamides, inhibitors of human sirtuin type 2 (SIRT2)Using mitochondrial sirtuins as drug targets: disease implications and available compounds.Sirtuin modulators.Synthesis and solid-state characterisation of 4-substituted methylidene oxindoles.Sirtuin inhibitors as anticancer agents.The discovery of a highly selective 5,6,7,8-tetrahydrobenzo[4,5]thieno[2,3-d]pyrimidin-4(3H)-one SIRT2 inhibitor that is neuroprotective in an in vitro Parkinson's disease model.The Current State of NAD(+) -Dependent Histone Deacetylases (Sirtuins) as Novel Therapeutic Targets.Use of the Monte Carlo Method for OECD Principles-Guided QSAR Modeling of SIRT1 Inhibitors.Ligand-based virtual screening and inductive learning for identification of SIRT1 inhibitors in natural products.The gramine route to pyrido[4,3-b]indol-3-ones - identification of a new cytotoxic lead.Facile synthesis of simple 2-oxindole-based compounds with promising antiproliferative activity.KH-TFMDI, a novel sirtuin inhibitor, alters the cytoskeleton and mitochondrial metabolism promoting cell death in Leishmania amazonensis.N'-Alkylaminosulfonyl Analogues of 6-Fluorobenzylideneindolinones with Desirable Physicochemical Profiles and Potent Growth Inhibitory Activities on Hepatocellular Carcinoma.NiO Nanoparticles: An Efficient Catalyst for the Multicomponent One-Pot Synthesis of Novel Spiro and Condensed Indole Derivatives
P2860
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P2860
Novel 3-arylideneindolin-2-ones as inhibitors of NAD+ -dependent histone deacetylases (sirtuins).
description
2010 nî lūn-bûn
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2010年の論文
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2010年学术文章
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2010年学术文章
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2010年学术文章
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2010年学术文章
@zh-hans
2010年学术文章
@zh-my
2010年学术文章
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2010年學術文章
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2010年學術文章
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name
Novel 3-arylideneindolin-2-one ...... stone deacetylases (sirtuins).
@en
Novel 3-arylideneindolin-2-ones as inhibitors of NAD+ -dependent histone deacetylases
@nl
type
label
Novel 3-arylideneindolin-2-one ...... stone deacetylases (sirtuins).
@en
Novel 3-arylideneindolin-2-ones as inhibitors of NAD+ -dependent histone deacetylases
@nl
prefLabel
Novel 3-arylideneindolin-2-one ...... stone deacetylases (sirtuins).
@en
Novel 3-arylideneindolin-2-ones as inhibitors of NAD+ -dependent histone deacetylases
@nl
P2093
P50
P356
P1476
Novel 3-arylideneindolin-2-one ...... stone deacetylases (sirtuins).
@en
P2093
Felicitas Lewrick
Franz Bracher
Julia M Wagner
Jörg Schemies
Regine Süss
Tobias Rumpf
Urszula Uciechowska
P304
P356
10.1021/JM901055U
P407
P577
2010-02-01T00:00:00Z