Aza-dibenzocyclooctynes for fast and efficient enzyme PEGylation via copper-free (3+2) cycloaddition.
about
Synthesis of heterobifunctional protein fusions using copper-free click chemistry and the aldehyde tagFluorophore targeting to cellular proteins via enzyme-mediated azide ligation and strain-promoted cycloadditionStrain-promoted alkyne-azide cycloadditions (SPAAC) reveal new features of glycoconjugate biosynthesisRapid Cu-free click chemistry with readily synthesized biarylazacyclooctynonesSynthesis of a fluorogenic cyclooctyne activated by Cu-free click chemistryA bioorthogonal quadricyclane ligationClick chemistry in complex mixtures: bioorthogonal bioconjugationBioorthogonal chemistry: strategies and recent developmentsNano-scale alignment of proteins on a flexible DNA backboneDevelopment and Applications of the Copper-Catalyzed Azide-Alkyne Cycloaddition (CuAAC) as a Bioorthogonal ReactionDecreasing Distortion Energies without Strain: Diazo-Selective 1,3-Dipolar Cycloadditions1,3-Dipolar Cycloadditions of Diazo Compounds in the Presence of AzidesClick-EM for imaging metabolically tagged nonprotein biomoleculesQuantitative, time-resolved proteomic analysis by combining bioorthogonal noncanonical amino acid tagging and pulsed stable isotope labeling by amino acids in cell cultureSelf-assembled micelles of amphiphilic PEGylated rapamycin for loading paclitaxel and resisting multidrug resistant cancer cells†Electronic supplementary information (ESI) available: Chemicals and reagents, detailed experimental procedures for materIn vivo virus-based macrofluorogenic probes target azide-labeled surface glycans in MCF-7 breast cancer cellsGlycans in pathogenic bacteria--potential for targeted covalent therapeutics and imaging agents.Multi-protein assemblies underlie the mesoscale organization of the plasma membrane.Difluorobenzocyclooctyne: synthesis, reactivity, and stabilization by beta-cyclodextrin.Protein modification by strain-promoted alkyne-nitrone cycloadditionReadily accessible bicyclononynes for bioorthogonal labeling and three-dimensional imaging of living cells.Two rapid catalyst-free click reactions for in vivo protein labeling of genetically encoded strained alkene/alkyne functionalities.Predictable and tunable half-life extension of therapeutic agents by controlled chemical release from macromolecular conjugates.Bioorthogonal reaction pairs enable simultaneous, selective, multi-target imaging.Genetically encoded unstrained olefins for live cell labeling with tetrazine dyes.Synthesis of macrocyclic tetrazoles for rapid photoinduced bioorthogonal 1,3-dipolar cycloaddition reactions.Highly accelerated inverse electron-demand cycloaddition of electron-deficient azides with aliphatic cyclooctynes.64Cu-labeled somatostatin analogues conjugated with cross-bridged phosphonate-based chelators via strain-promoted click chemistry for PET imaging: in silico through in vivo studiesMetal-free sequential [3 + 2]-dipolar cycloadditions using cyclooctynes and 1,3-dipoles of different reactivityBioactive DNA-peptide nanotubes enhance the differentiation of neural stem cells into neurons.A Mild, Large-Scale Synthesis of 1,3-Cyclooctanedione: Expanding Access to Difluorinated Cyclooctyne for Copper-Free Click Chemistry.Near-infrared fluorescence imaging of CD13 receptor expression using a novel Cy5.5-labeled dimeric NGR peptide.1,3-Dipolar cycloaddition reactivities of perfluorinated aryl azides with enamines and strained dipolarophilesFrom mechanism to mouse: a tale of two bioorthogonal reactionsOrdered and kinetically discrete sequential protein release from biodegradable thin films.F-18 Labeled RGD Probes Based on Bioorthogonal Strain-Promoted Click Reaction for PET Imaging.Rapid and Specific Enrichment of Culturable Gram Negative Bacteria Using Non-Lethal Copper-Free Click Chemistry Coupled with Magnetic Beads Separation.Non-Catalyzed Click Reactions of ADIBO Derivatives with 5-Methyluridine Azides and Conformational Study of the Resulting Triazoles.Polar dibenzocyclooctynes for selective labeling of extracellular glycoconjugates of living cellsReactivity of biarylazacyclooctynones in copper-free click chemistry
P2860
Q24601129-B6D49CFA-5BF7-4A5E-A87C-A2032753A0A7Q24615188-A8F35BBF-57C5-4819-BAB8-A2E291299661Q24622521-50DBA487-B34E-4EBC-8DA0-7F4ECD5F6EE3Q24623486-F7B6125F-D233-4A7B-BA26-134E1755C681Q24625140-D03B0DD0-5BB6-4A43-9A9A-D3CD5EFCD7DBQ24632599-DFCB825A-04D2-49F8-B5FC-A517E2B61605Q26828895-EF44A3D6-E5BA-4F58-A6CA-07358A588ED2Q27025530-2180ED2C-DA15-4987-8B09-A9C78FC40F00Q27324588-4C04CD0A-F7D8-450A-867B-D1CD9FD1A776Q28079295-61C32ECB-9455-41AE-B54C-B38DF885F1EAQ28817848-BC90E39C-3322-42BA-B64A-A31782CEB71AQ28817850-EA2936A3-F66D-47E5-8215-7A1C510EA058Q28833849-7D63CEC7-EC51-4058-9350-48D10D453D83Q30577688-EE8B949F-711C-4FA5-A83C-746139AECA3AQ30900326-7A1836F2-0DDC-4636-9462-9D72905E0AB3Q33567139-6EA45D4F-6C2E-4F73-9789-BA5470C4B8DCQ33725733-9A0748AE-E885-4DFD-9F5E-A7445D673F3AQ34014673-46E44DB8-4302-4A96-8A1B-203A38A221F9Q34072621-0726E571-C695-4493-9288-E4C8588C61C2Q34106478-6C710CC3-EAAD-4F5F-A6D1-892ADA9B76F6Q34139183-A175F63E-C355-4179-A80E-F7406EBAEB22Q34196992-33DBFF00-1F59-4BB0-A44C-732472650F37Q34219669-2AFE01CB-92C4-456E-B73B-2C87603A56CAQ34240233-D08AA516-EB69-4498-ACA9-662D0495684DQ34287968-C995092B-AD09-402B-95E2-FC2F9FE964D8Q34441302-1A166D70-F97F-4022-BFF0-C42510602D59Q34446996-5430A92E-4638-4A6E-BFFD-866D8F65D78DQ34665668-7752F4FB-1289-4DE3-8AFE-5732B2F232E5Q34815788-1AAF2BF6-43D1-4888-B44E-E9DE526D1A4BQ34977505-ECF472BC-4AFB-4896-BCB6-52A69CA37A6DQ35012785-780B4F26-5C62-4D44-BDDF-4F747C97D614Q35126828-0618CD63-65F7-41F5-88E4-0CE9536EFABEQ35152185-ECFA82FE-36E9-4C0E-AEAA-4E6472180A2EQ35252297-58AD202F-9F7F-490C-A716-46A11B58247AQ35295689-67CB593B-0F2A-4A69-B92C-D222462E491BQ35379070-6D4681D9-DE3D-4762-AD5E-630B93493FBAQ35660026-8B6B129C-AF2D-48B3-A79C-B39E62A0FECAQ35870303-D0744959-F341-42A9-B450-928937C60D79Q35871298-BAA0332D-EA43-4379-8337-DFFE57F58312Q36011672-5F34A202-CD0C-483C-9245-67E3373A0C31
P2860
Aza-dibenzocyclooctynes for fast and efficient enzyme PEGylation via copper-free (3+2) cycloaddition.
description
2009 nî lūn-bûn
@nan
2009年の論文
@ja
2009年学术文章
@wuu
2009年学术文章
@zh
2009年学术文章
@zh-cn
2009年学术文章
@zh-hans
2009年学术文章
@zh-my
2009年学术文章
@zh-sg
2009年學術文章
@yue
2009年學術文章
@zh-hant
name
Aza-dibenzocyclooctynes for fa ...... pper-free (3+2) cycloaddition.
@en
Aza-dibenzocyclooctynes for fast and efficient enzyme PEGylation via copper-free
@nl
type
label
Aza-dibenzocyclooctynes for fa ...... pper-free (3+2) cycloaddition.
@en
Aza-dibenzocyclooctynes for fast and efficient enzyme PEGylation via copper-free
@nl
prefLabel
Aza-dibenzocyclooctynes for fa ...... pper-free (3+2) cycloaddition.
@en
Aza-dibenzocyclooctynes for fast and efficient enzyme PEGylation via copper-free
@nl
P2093
P356
P1476
Aza-dibenzocyclooctynes for fa ...... pper-free (3+2) cycloaddition.
@en
P2093
Floris L van Delft
Floris P J T Rutjes
Jan C M van Hest
Marjoke F Debets
Sander S van Berkel
Sanne Schoffelen
P356
10.1039/B917797C
P407
P577
2009-11-06T00:00:00Z