Robust Endoplasmic Reticulum-Associated Degradation of Rhodopsin Precedes Retinal Degeneration.
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A small molecule mitigates hearing loss in a mouse model of Usher syndrome IIIRecent Insights into the Role of Unfolded Protein Response in ER Stress in Health and Disease.Protein misfolding and the pathogenesis of ABCA4-associated retinal degenerations.Involvement of Endoplasmic Reticulum Stress in TULP1 Induced Retinal Degeneration.A High-Throughput Drug Screening Strategy for Detecting Rhodopsin P23H Mutant Rescue and Degradation.Erythropoietin Slows Photoreceptor Cell Death in a Mouse Model of Autosomal Dominant Retinitis Pigmentosa.Endoplasmic Reticulum-Targeted Subunit Toxins Provide a New Approach to Rescue Misfolded Mutant Proteins and Revert Cell Models of Genetic Diseases.In Vivo Visualization of Endoplasmic Reticulum Stress in the Retina Using the ERAI Reporter MouseLight Induces Ultrastructural Changes in Rod Outer and Inner Segments, Including Autophagy, in a Transgenic Xenopus laevis P23H Rhodopsin Model of Retinitis Pigmentosa.NLRP3 inflammasome activation drives bystander cone photoreceptor cell death in a P23H rhodopsin model of retinal degenerationPhotoreceptor Cells Influence Retinal Vascular Degeneration in Mouse Models of Retinal Degeneration and DiabetesAchromatopsia mutations target sequential steps of ATF6 activation.Neuroprotective Strategy in Retinal Degeneration: Suppressing ER Stress-Induced Cell Death via Inhibition of the mTOR Signal.Rescue of mutant rhodopsin traffic by metformin-induced AMPK activation accelerates photoreceptor degeneration.Multiple Mechanisms of Unfolded Protein Response-Induced Cell DeathPhotoreceptor Transplantation in Late Stage Retinal Degeneration.Endoplasmic reticulum stress in human photoreceptor diseases.TM7SF3, a novel p53-regulated homeostatic factor, attenuates cellular stress and the subsequent induction of the unfolded protein response.Wild-type opsin does not aggregate with a misfolded opsin mutant.Transcriptome profiling of NIH3T3 cell lines expressing opsin and the P23H opsin mutant identifies candidate drugs for the treatment of retinitis pigmentosa.Ablation of Chop Transiently Enhances Photoreceptor Survival but Does Not Prevent Retinal Degeneration in Transgenic Mice Expressing Human P23H Rhodopsin.The molecular and cellular basis of rhodopsin retinitis pigmentosa reveals potential strategies for therapy.Phenotypic characterization of P23H and S334ter rhodopsin transgenic rat models of inherited retinal degeneration.The role of the ER stress-response protein PERK in rhodopsin retinitis pigmentosa.Increased proteasomal activity supports photoreceptor survival in inherited retinal degeneration.Dominant and recessive mutations in rhodopsin activate different cell death pathways.A novel small molecule chaperone of rod opsin and its potential therapy for retinal degeneration.Dark Rearing Does Not Prevent Rod Oxidative Stress In Vivo in Pde6brd10 Mice.
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P2860
Robust Endoplasmic Reticulum-Associated Degradation of Rhodopsin Precedes Retinal Degeneration.
description
2014 nî lūn-bûn
@nan
2014年の論文
@ja
2014年学术文章
@wuu
2014年学术文章
@zh
2014年学术文章
@zh-cn
2014年学术文章
@zh-hans
2014年学术文章
@zh-my
2014年学术文章
@zh-sg
2014年學術文章
@yue
2014年學術文章
@zh-hant
name
Robust Endoplasmic Reticulum-A ...... Precedes Retinal Degeneration.
@en
Robust Endoplasmic Reticulum-A ...... Precedes Retinal Degeneration.
@nl
type
label
Robust Endoplasmic Reticulum-A ...... Precedes Retinal Degeneration.
@en
Robust Endoplasmic Reticulum-A ...... Precedes Retinal Degeneration.
@nl
prefLabel
Robust Endoplasmic Reticulum-A ...... Precedes Retinal Degeneration.
@en
Robust Endoplasmic Reticulum-A ...... Precedes Retinal Degeneration.
@nl
P2093
P2860
P1476
Robust Endoplasmic Reticulum-A ...... Precedes Retinal Degeneration
@en
P2093
Carissa Messah
Douglas Yasumura
Heike Kroeger
Jonathan H Lin
Judith A Coppinger
Krzysztof Palczewski
Matthew M LaVail
Michael T Matthes
Sanae Sakami
P2860
P2888
P304
P356
10.1007/S12035-014-8881-8
P577
2014-10-02T00:00:00Z
P5875
P6179
1047256304