about
Novel paramagnetic macromolecular complexes derived from the linkage of a macrocyclic Gd(III) complex to polyamino acids through a squaric acid moiety.Solution properties of the Ln(III) complexes of a novel octadentate chelator with rigidified iminodiacetate arms.[GdPCP2A(H(2)O)(2)](-): a paramagnetic contrast agent designed for improved applications in magnetic resonance imaging.Combined high resolution NMR and 1H and 17O relaxometric study sheds light on the solution structure and dynamics of the lanthanide(III) complexes of HPDO3A.Self-aggregated dinuclear lanthanide(III) complexes as potential bimodal probes for magnetic resonance and optical imaging.Aryl-phosphonate lanthanide complexes and their fluorinated derivatives: investigation of their unusual relaxometric behavior and potential application as dual frequency 1H/19F MRI probes.Hyperfine coupling constants on inner-sphere water molecules of a triazacyclononane-based Mn(II) complex and related systems relevant as MRI contrast agents.New calcium-selective smart contrast agents for magnetic resonance imaging.Structural, luminescence, and NMR studies of the reversible binding of acetate, lactate, citrate, and selected amino acids to chiral diaqua ytterbium, gadolinium, and europium complexes.Structural variations across the lanthanide series of macrocyclic DOTA complexes: insights into the design of contrast agents for magnetic resonance imaging.Ternary complexes between cationic GdIII chelates and anionic metabolites in aqueous solution: an NMR relaxometric study.Picolinate-containing macrocyclic Mn2+ complexes as potential MRI contrast agents.Dendrimeric β-cyclodextrin/Gd(III) chelate supramolecular host-guest adducts as high-relaxivity MRI probes.High relaxivity Mn(2+)-based MRI contrast agents.Lower denticity leading to higher stability: structural and solution studies of Ln(III)-OBETA complexes.A highly stable gadolinium complex with a fast, associative mechanism of water exchange.NMR relaxometric study of new Gd(III) macrocyclic complexes and their interaction with human serum albumin.Novel gadolinium(III) polyaminocarboxylate macrocyclic complexes as potential magnetic resonance imaging contrast agents.Gadolinium(III) 1,2-hydroxypyridonate-based complexes: toward MRI contrast agents of high relaxivity.Hetero-tripodal hydroxypyridonate gadolinium complexes: syntheses, relaxometric properties, water exchange dynamics, and human serum albumin binding.Dendrimeric gadolinium chelate with fast water exchange and high relaxivity at high magnetic field strength.A multinuclear NMR relaxometry study of ternary adducts formed between heptadentate Gd(III) chelates and L-lactate.Mono-, bi-, and trinuclear bis-hydrated Mn(2+) complexes as potential MRI contrast agents.Towards the rational design of MRI contrast agents: a practical approach to the synthesis of gadolinium complexes that exhibit optimal water exchangeTris(pyrone) chelates of Gd(III) as high solubility MRI-CA.Glycoconjugates of gadolinium complexes for MRI applications.Tuning the coordination number of hydroxypyridonate-based gadolinium complexes: implications for MRI contrast agents.Fe(III)-templated Gd(III) self-assemblies-a new route toward macromolecular MRI contrast agentsSubstituent effects on Gd(III)-based MRI contrast agents: optimizing the stability and selectivity of the complex and the number of coordinated water molecules.Synthesis and characterisation of dimeric eight-coordinate lanthanide(III) complexes of a macrocyclic tribenzylphosphinate ligand.Gd-enhanced MR images of substrates other than water.On the role of the counter-ion in defining water structure and dynamics: order, structure and dynamics in hydrophilic and hydrophobic gadolinium salt complexes.Highly soluble tris-hydroxypyridonate Gd(III) complexes with increased hydration number, fast water exchange, slow electronic relaxation, and high relaxivityEvaluation of Water Exchange Kinetics on [Ln(AAZTAPh-NO2)(H2O)q](x) Complexes Using Proton Nuclear Magnetic Resonance.Amphiphilic Ditopic Bis-Aqua Gd-AAZTA-like Complexes Enhance Relaxivity of Lipidic MRI Nanoprobes.Optimized relaxivity and stability of [Gd(H(2,2)-1,2-HOPO)(H2O)]- for use as an MRI contrast agent.An esterase-activated magnetic resonance contrast agent.1,2-hydroxypyridonates as contrast agents for magnetic resonance imaging: TREN-1,2-HOPO.Definition of the Labile Capping Bond Effect in Lanthanide Complexes.High relaxivity gadolinium hydroxypyridonate-viral capsid conjugates: nanosized MRI contrast agents.
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description
hulumtues
@sq
researcher
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wetenschapper
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հետազոտող
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name
Mauro Botta
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Mauro Botta
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Mauro Botta
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Mauro Botta
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Mauro Botta
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type
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Mauro Botta
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Mauro Botta
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Mauro Botta
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Mauro Botta
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Mauro Botta
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Botta M
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prefLabel
Mauro Botta
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Mauro Botta
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Mauro Botta
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Mauro Botta
@nl
Mauro Botta
@sl
P106
P1153
56990760500
57192688066
P21
P31
P496
0000-0003-4192-355X