The Quintiles Prize Lecture 2004. The identification of the adenosine A2B receptor as a novel therapeutic target in asthma.
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Adenosine receptors as therapeutic targetsAdenosine receptors: therapeutic aspects for inflammatory and immune diseases.Adenosine receptors and asthma.The role of adenosine signaling in sickle cell therapeuticsThymoquinone, the main constituent of Nigella sativa, affects adenosine receptors in asthmatic guinea pigsDiscovery of LAS101057: A Potent, Selective, and Orally Efficacious A2B Adenosine Receptor Antagonist.Pyrazolo derivatives as potent adenosine receptor antagonists: an overview on the structure-activity relationshipsIntroduction to adenosine receptors as therapeutic targets.Disparity in FcεRI-induced degranulation of primary human lung and skin mast cells exposed to adenosine.Enhanced mast cell activation in mice deficient in the A2b adenosine receptor.A2B adenosine receptors regulate the mucus clearance component of the lung's innate defense system.Adenosine influences myeloid cells to inhibit aeroallergen sensitization.G protein-coupled receptor connectivity to NF-kappaB in inflammation and cancer.Adenosine signaling and the regulation of chronic lung disease.Mast cells in asthma--state of the art.Prostaglandin E₂regulation of cystic fibrosis transmembrane conductance regulator activity and airway surface liquid volume requires gap junctional communicationCharacterization of human and rodent native and recombinant adenosine A(2B) receptors by radioligand binding studies.Novel selective antagonist radioligands for the pharmacological study of A(2B) adenosine receptors.P1 receptors and cytokine secretion.Adenosine closes the K+ channel KCa3.1 in human lung mast cells and inhibits their migration via the adenosine A2A receptor.The Effect of Adenosine A2A and A2B Antagonists on Tracheal Responsiveness, Serum Levels of Cytokines and Lung Inflammation in Guinea Pig Model of Asthma.Progress in the discovery of selective, high affinity A(2B) adenosine receptor antagonists as clinical candidates.Mechanism of adenosine-induced airways obstruction in allergic guinea pigs.Adenosine induces a cholinergic tracheal reflex contraction in guinea pigs in vivo via an adenosine A1 receptor-dependent mechanism.Theophylline and its metabolites produce a stimulating cholinergic effect on the small intestine and a nonadrenergic noncholinergic relaxing effect on the colon: a comparative study in the rabbit intestine.A role for neural pathways in adenosine-induced bronchoconstriction.
P2860
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P2860
The Quintiles Prize Lecture 2004. The identification of the adenosine A2B receptor as a novel therapeutic target in asthma.
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2005 nî lūn-bûn
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2005年の論文
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2005年学术文章
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2005年学术文章
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2005年学术文章
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2005年学术文章
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2005年学术文章
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The Quintiles Prize Lecture 20 ...... therapeutic target in asthma.
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The Quintiles Prize Lecture 20 ...... therapeutic target in asthma.
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type
label
The Quintiles Prize Lecture 20 ...... therapeutic target in asthma.
@en
The Quintiles Prize Lecture 20 ...... therapeutic target in asthma.
@nl
prefLabel
The Quintiles Prize Lecture 20 ...... therapeutic target in asthma.
@en
The Quintiles Prize Lecture 20 ...... therapeutic target in asthma.
@nl
P2860
P356
P1476
The Quintiles Prize Lecture 20 ...... therapeutic target in asthma.
@en
P2860
P304
P356
10.1038/SJ.BJP.0706272
P407
P577
2005-08-01T00:00:00Z