Metabolic remodeling induced by mitochondrial aldehyde stress stimulates tolerance to oxidative stress in the heart.
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Glu504Lys Single Nucleotide Polymorphism of Aldehyde Dehydrogenase 2 Gene and the Risk of Human DiseasesHaploinsufficiency of akt1 prolongs the lifespan of miceEffects of the common polymorphism in the human aldehyde dehydrogenase 2 (ALDH2) gene on the lungAldehyde dehydrogenase 1B1: molecular cloning and characterization of a novel mitochondrial acetaldehyde-metabolizing enzymeA missense single nucleotide polymorphism in the ALDH2 gene, rs671, is associated with hip fractureImpact of chronic low to moderate alcohol consumption on blood lipid and heart energy profile in acetaldehyde dehydrogenase 2-deficient mice.Mitochondrial aldehyde dehydrogenase and cardiac diseases.Preventive effects of Chlorella on skeletal muscle atrophy in muscle-specific mitochondrial aldehyde dehydrogenase 2 activity-deficient mice.Targeting aldehyde dehydrogenase 2: new therapeutic opportunities.Isoflurane preconditioning confers cardioprotection by activation of ALDH2.Metabolomic profiling analysis reveals chamber-dependent metabolite patterns in the mouse heart.Aldehydic load and aldehyde dehydrogenase 2 profile during the progression of post-myocardial infarction cardiomyopathy: benefits of Alda-1ALDH2(E487K) mutation increases protein turnover and promotes murine hepatocarcinogenesis.Aldehyde dehydrogenase-2 protects against myocardial infarction-related cardiac fibrosis through modulation of the Wnt/β-catenin signaling pathway.Stressing the heart of the matter: re-thinking the mechanisms underlying therapeutic effects of n-3 polyunsaturated fatty acids.The histone 3 lysine 9 methyltransferase inhibitor chaetocin improves prognosis in a rat model of high salt diet-induced heart failure.Cardiovascular redox and ox stress proteomics.ALDH2 activator inhibits increased myocardial infarction injury by nitroglycerin tolerance.Effects of caloric restriction on cardiac oxidative stress and mitochondrial bioenergetics: potential role of cardiac sirtuins.Reducing the serine availability complements the inhibition of the glutamine metabolism to block leukemia cell growth.Effect of overexpression of human aldehyde dehydrogenase 2 in LLC-PK1 cells on glyceryl trinitrate biotransformation and cGMP accumulation.Aldehyde stress and up-regulation of Nrf2-mediated antioxidant systems accompany functional adaptations in cardiac mitochondria from mice fed n-3 polyunsaturated fatty acids.Focus on: The cardiovascular system: what did we learn from the French (Paradox)?Mitochondrial function and energy metabolism in neuronal HT22 cells resistant to oxidative stress.Capillary endothelial fatty acid binding proteins 4 and 5 play a critical role in fatty acid uptake in heart and skeletal muscle.Metabolomic Signature of Coronary Artery Disease in Type 2 Diabetes MellitusRecent progress toward hydrogen medicine: potential of molecular hydrogen for preventive and therapeutic applications.Cell bioenergetics in Leghorn male hepatoma cells and immortalized chicken liver cells in response to 4-hydroxy 2-nonenal-induced oxidative stress.Roles of defective ALDH2 polymorphism on liver protection and cancer development.Mitochondrial dysfunction in cancer: Potential roles of ATF5 and the mitochondrial UPR.Molecular hydrogen stimulates the gene expression of transcriptional coactivator PGC-1α to enhance fatty acid metabolism.Regulation of human mitochondrial aldehyde dehydrogenase (ALDH-2) activity by electrophiles in vitro.ALDH2 attenuates Dox-induced cardiotoxicity by inhibiting cardiac apoptosis and oxidative stress.Comparative genomics, molecular evolution and computational modeling of ALDH1B1 and ALDH2.Beyond reactive oxygen species: aldehydes as arbitrators of alarm and adaptation.A critical role of fatty acid binding protein 4 and 5 (FABP4/5) in the systemic response to fasting.Association of DJ-1/PTEN/AKT- and ASK1/p38-mediated cell signalling with ischaemic cardiomyopathy.Antimicrobial activity and mechanism of Larch bark procyanidins against Staphylococcus aureus.Ethanol reduces lifespan, body weight, and serum alanine aminotransferase level of aldehyde dehydrogenase 2 knockout mouse.Effects of molecular hydrogen assessed by an animal model and a randomized clinical study on mild cognitive impairment.
P2860
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P2860
Metabolic remodeling induced by mitochondrial aldehyde stress stimulates tolerance to oxidative stress in the heart.
description
2009 nî lūn-bûn
@nan
2009年の論文
@ja
2009年学术文章
@wuu
2009年学术文章
@zh
2009年学术文章
@zh-cn
2009年学术文章
@zh-hans
2009年学术文章
@zh-my
2009年学术文章
@zh-sg
2009年學術文章
@yue
2009年學術文章
@zh-hant
name
Metabolic remodeling induced b ...... oxidative stress in the heart.
@en
Metabolic remodeling induced b ...... oxidative stress in the heart.
@nl
type
label
Metabolic remodeling induced b ...... oxidative stress in the heart.
@en
Metabolic remodeling induced b ...... oxidative stress in the heart.
@nl
prefLabel
Metabolic remodeling induced b ...... oxidative stress in the heart.
@en
Metabolic remodeling induced b ...... oxidative stress in the heart.
@nl
P2093
P1433
P1476
Metabolic remodeling induced b ...... oxidative stress in the heart
@en
P2093
Alexander Martin Wolf
Fumiyuki Hattori
Hideyuki Ito
Hiroki Nakanishi
Ikuroh Ohsawa
Keiichi Fukuda
Ken Shinmura
Kiyomi Nishimaki
Makoto Suematsu
P304
P356
10.1161/CIRCRESAHA.109.206607
P577
2009-10-08T00:00:00Z