Warfarin and UDP-glucuronosyltransferases: writing a new chapter of metabolism.
about
Multiple UDP-glucuronosyltransferases in human liver microsomes glucuronidate both R- and S-7-hydroxywarfarin into two metabolites.Hydroxywarfarin metabolites potently inhibit CYP2C9 metabolism of S-warfarin.Moderate hyperbilirubinemia improves renal hemodynamics in ANG II-dependent hypertensionWarfarin glycosylation invokes a switch from anticoagulant to anticancer activity.Pharmacokinetic Drug Interaction Studies with Enzalutamide.First-pass metabolism via UDP-glucuronosyltransferase: a barrier to oral bioavailability of phenolics.Assays and applications in warfarin metabolism: what we know, how we know it and what we need to know.Assaying embryotoxicity in the test tube: current limitations of the embryonic stem cell test (EST) challenging its applicability domain.Human UDP-Glucuronosyltransferase 2B4 and 2B7 Are Responsible for Naftopidil Glucuronidation in Vitro.Influence of UDP-Glucuronosyltransferase Polymorphisms on Stable Warfarin Doses in Patients with Mechanical Cardiac Valves.
P2860
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P2860
Warfarin and UDP-glucuronosyltransferases: writing a new chapter of metabolism.
description
2010 nî lūn-bûn
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name
Warfarin and UDP-glucuronosyltransferases: writing a new chapter of metabolism.
@en
Warfarin and UDP-glucuronosyltransferases: writing a new chapter of metabolism.
@nl
type
label
Warfarin and UDP-glucuronosyltransferases: writing a new chapter of metabolism.
@en
Warfarin and UDP-glucuronosyltransferases: writing a new chapter of metabolism.
@nl
prefLabel
Warfarin and UDP-glucuronosyltransferases: writing a new chapter of metabolism.
@en
Warfarin and UDP-glucuronosyltransferases: writing a new chapter of metabolism.
@nl
P2860
P1476
Warfarin and UDP-glucuronosyltransferases: writing a new chapter of metabolism
@en
P2093
Jeffery H Moran
P2860
P356
10.3109/03602530903209395
P407
P577
2010-02-01T00:00:00Z