Probucol increases glutathione peroxidase-1 activity and displays long-lasting protection against methylmercury toxicity in cerebellar granule cells. - Wikidata - wikimedia - TriplyDB

Probucol increases glutathione peroxidase-1 activity and displays long-lasting protection against methylmercury toxicity in cerebellar granule cells.

Probucol increases glutathione peroxidase-1 activity and displays long-lasting protection against methylmercury toxicity in cerebellar granule cells.

http://www.wikidata.org/entity/Q43273391

about

Heavy Metals and Human Health: Mechanistic Insight into Toxicity and Counter Defense System of Antioxidants Metals, oxidative stress and neurodegeneration: a focus on iron, manganese and mercury Comparative study on the response of rat primary astrocytes and microglia to methylmercury toxicity Oxidative stress in MeHg-induced neurotoxicity Mechanisms and Modifiers of Methylmercury-Induced Neurotoxicity Probucol increases striatal glutathione peroxidase activity and protects against 3-nitropropionic acid-induced pro-oxidative damage in rats Protective actions of 17β-estradiol and progesterone on oxidative neuronal injury induced by organometallic compounds.Methylmercury alters the activities of Hsp90 client proteins, prostaglandin E synthase/p23 (PGES/23) and nNOS.Structure-activity relationship of flavonoids derived from medicinal plants in preventing methylmercury-induced mitochondrial dysfunction.Glutathione peroxidase-1 in health and disease: from molecular mechanisms to therapeutic opportunities Mechanisms of methylmercury-induced neurotoxicity: evidence from experimental studies.Antioxidant effects of Dendropanax morbifera Léveille extract in the hippocampus of mercury-exposed rats Probucol ameliorates renal and metabolic sequelae of primary CoQ deficiency in Pdss2 mutant mice Role of calcium and mitochondria in MeHg-mediated cytotoxicity.Methylmercury Causes Blood-Brain Barrier Damage in Rats via Upregulation of Vascular Endothelial Growth Factor Expression Dietary selenium fails to influence cigarette smoke-induced lung tumorigenesis in A/J mice Does methylmercury-induced hypercholesterolemia play a causal role in its neurotoxicity and cardiovascular disease?NAD+ Supplementation Attenuates Methylmercury Dopaminergic and Mitochondrial Toxicity in Caenorhabditis Elegans.Modulation of methylmercury uptake by methionine: prevention of mitochondrial dysfunction in rat liver slices by a mimicry mechanism Inhibition of ERK-DLP1 signaling and mitochondrial division alleviates mitochondrial dysfunction in Alzheimer's disease cybrid cell Mercury and metabolic syndrome: a review of experimental and clinical observations.Biomarkers of mercury toxicity: Past, present, and future trends.A review of toxicity and mechanisms of individual and mixtures of heavy metals in the environment.Methylmercury and brain development: A review of recent literature.Succinobucol, a Lipid-Lowering Drug, Protects Against 3-Nitropropionic Acid-Induced Mitochondrial Dysfunction and Oxidative Stress in SH-SY5Y Cells via Upregulation of Glutathione Levels and Glutamate Cysteine Ligase Activity.Comparative study on methyl- and ethylmercury-induced toxicity in C6 glioma cells and the potential role of LAT-1 in mediating mercurial-thiol complexes uptake.Methylmercury-induced alterations in astrocyte functions are attenuated by ebselen.A positive correlation between mercury and oxidative stress-related gene expression (GPX3 and GSTM3) is measured in female Double-crested Cormorant blood.Methionine stimulates motor impairment and cerebellar mercury deposition in methylmercury-exposed mice.Excitotoxicity and oxidative damages induced by methylmercury in rat cerebral cortex and the protective effects of tea polyphenols.Mechanisms of manganese-induced neurotoxicity in primary neuronal cultures: the role of manganese speciation and cell type.Protective effects of memantine against methylmercury-induced glutamate dyshomeostasis and oxidative stress in rat cerebral cortex.Probucol affords neuroprotection in a 6-OHDA mouse model of Parkinson's disease.Low in situ expression of antioxidative enzymes in rat cerebellar granular cells susceptible to methylmercury.Sulforaphane Prevents Methylmercury-Induced Oxidative Damage and Excitotoxicity Through Activation of the Nrf2-ARE Pathway.The protective role of tea polyphenols against methylmercury-induced neurotoxic effects in rat cerebral cortex via inhibition of oxidative stress.Preventive effects of dextromethorphan on methylmercury-induced glutamate dyshomeostasis and oxidative damage in rat cerebral cortex.Organoselenium compounds as mimics of selenoproteins and thiol modifier agents.Methylmercury-Induced Neurotoxicity: Focus on Pro-oxidative Events and Related Consequences.Sex- and structure-specific differences in antioxidant responses to methylmercury during early development.

P2860

Q26774259-820D2432-9506-414F-8D35-0EBC78E222D8 Q26863224-7DBA8042-F9E4-4A34-B197-7A359BF6F3B7 Q28388040-AF0444B7-0EBC-4FB5-AC3F-3C99F5118431 Q28391544-AD166347-6C07-46A9-8FA6-C2B876797DFE Q28392699-A263E8E8-AF97-4F04-85E0-65747B9F4334 Q28533959-58280AA7-2DA1-4870-B192-BFFF3C07EB98 Q30416021-C9367941-E98D-413C-BA05-7F64486B2339 Q33650364-81422636-7351-441F-BA16-6266BA491BF9 Q34356383-D95AF021-1ED4-4927-9B2C-34E0EAC7D41C Q35173610-BA8FE01A-A6AA-46C0-9F75-E1EA0E123381 Q35243263-51FB94D1-F4B9-4B20-AD48-62049C8DD1DF Q35706477-3AFC94C6-96A9-42B1-91E2-ACE1C32EAF15 Q36088905-1BAC9B42-7A66-4760-9FB3-80312D4A9726 Q36183970-1BC750B7-C2DB-4163-9A80-C8EC77C177C8 Q36258809-B039DE91-A196-4538-A971-399B9D6D2F2A Q36704246-F723D851-18BB-4130-822C-4E68657232BE Q36752705-96C81B15-78CB-4B5E-B259-867E182E66D2 Q37023627-E67A4AEB-FE3C-4AAA-B735-4578DE00ABEB Q37029575-FE4CB0A4-EDD4-4CC3-8421-083DF4126518 Q37709664-D332AC73-2960-4187-AC60-67C56D602D3A Q38336854-5B629764-AC2C-4E9A-A2FA-3E1A270101B9 Q38734752-FBAC80B5-871E-4FC9-9725-0B0E7BC9A0A5 Q38769141-EB086A69-C0CD-4600-BDDF-3696A98BFA39 Q38778442-D5E53F95-33A7-4B55-8A22-C0DA81FC2F96 Q38916576-A58290DE-EDC7-4030-B530-EB697C814475 Q39145107-50495F7C-196E-4C5D-9879-8DFE582F2889 Q41943393-61B37472-D803-450E-A54F-9E2BFB82A1A2 Q42705796-89E8A105-B2FB-4F5C-9B3C-3D7A49367612 Q42706691-C9096605-3C25-4423-951F-D3D3A810A67B Q42722535-EE033603-5E99-4766-9880-E2E8D56FB892 Q42726630-2AF01093-4533-4C81-92CA-97BFC17C7115 Q43615387-B3CF7231-246E-408D-A369-67688C007219 Q44047703-3E90AB1E-064A-42C3-8078-29AD5D47F6F1 Q45912115-671F3883-932E-46EB-B1A7-2ADE9A9D051F Q46613940-BB8EC809-7FE0-49F9-9A9A-295BB412D25A Q46894903-984DDF71-4AA5-4F06-8E30-E1AAC7370E34 Q46895189-3DEDC439-41DE-496B-8AAB-4B3FB92E4FC2 Q47370972-3C894CB9-64A7-4D56-A2EB-BB24438001B1 Q47827302-80C94414-D40F-4AE8-9097-9F24C9958BAD Q48036280-B603C793-35F5-4480-8454-164CA83DC940

P2860

Probucol increases glutathione peroxidase-1 activity and displays long-lasting protection against methylmercury toxicity in cerebellar granule cells.

http://www.wikidata.org/entity/Q43273391

description

2009 nî lūn-bûn

@nan

2009年の論文

@ja

2009年学术文章

@wuu

2009年学术文章

@zh

2009年学术文章

@zh-cn

2009年学术文章

@zh-hans

2009年学术文章

@zh-my

2009年学术文章

@zh-sg

2009年學術文章

@yue

2009年學術文章

@zh-hant

name

Probucol increases glutathione ...... y in cerebellar granule cells.

@en

Probucol increases glutathione ...... y in cerebellar granule cells.

@nl

type

label

Probucol increases glutathione ...... y in cerebellar granule cells.

@en

Probucol increases glutathione ...... y in cerebellar granule cells.

@nl

prefLabel

Probucol increases glutathione ...... y in cerebellar granule cells.

@en

Probucol increases glutathione ...... y in cerebellar granule cells.

@nl

P1433

Q43273391-F2B340C8-CF56-4039-A9C4-C0A7088EFE40

P1476

Q43273391-7BC15351-8DA4-4401-8311-D4DC6DD7825F

P2093

Q43273391-5C4D0595-69EA-485E-AC7C-47247F723456

Q43273391-A2DCD244-6739-4B38-8D93-C1C80E855CCC

Q43273391-ADAE3723-FC63-4584-83F0-9D284E0F3425

Q43273391-E271E59B-2F32-4084-A4A4-F2E54D0ADBB9

Q43273391-F4ED3317-A5D8-4BCF-BEEB-0B1461E70654

P2860

Q43273391-03E8A96C-6F81-47EF-A254-C1AF452D15DB

Q43273391-06FEF08B-FDF7-408E-9E8D-3124F7A866BA

Q43273391-0C1149D2-AAFD-4A7E-826A-4C5C4E9D9438

Q43273391-0E9CB83C-CE62-4493-8E47-62A50865B05A

Q43273391-2A1BCB67-8B10-4E56-8B0F-FF936DA950B0

Q43273391-2B4F4E19-ED2B-485A-8FB3-002AEEED974E

Q43273391-2CD06AF8-9756-47E7-A84E-E27D6A73A9B6

Q43273391-356B86FC-FAB3-4FC2-9DF6-2BAD9126BD29

Q43273391-74213037-8DD4-4995-8EEE-6C689243AB9B

Q43273391-8E5DC6C0-53EC-405A-9EF7-30A74C3F22F7

P304

Q43273391-E7AB090B-0E1E-4759-90DD-0385CFD87152

P31

Q43273391-A5536661-21D6-4215-BDC8-BF846121E81B

P356

Q43273391-C6129140-DF6E-4668-8A3A-0E07DD2BD048

P433

Q43273391-401390F8-B767-4EC6-893C-F4ED42A70E05

P478

Q43273391-F213DB46-E68C-43FA-AE40-92087D26A012

P50

Q43273391-96ABF62C-3211-423C-98A0-89194FE90F1E

Q43273391-DC6B93B8-4423-400D-8762-F2AC8C0FF97F

P577

Q43273391-441374BE-F73F-439E-9DE0-9BD55EECA28F

P698

Q43273391-48DE3C21-2DB0-4487-904E-DFB82D8312A1

P356

P1433

Toxicological Sciences

P1476

Probucol increases glutathione ...... ty in cerebellar granule cells

@en

P2093

Cristina Suñol

http://www.w3.org/2001/XMLSchema#string

Francisco Campos

http://www.w3.org/2001/XMLSchema#string

Iolanda Vendrell

http://www.w3.org/2001/XMLSchema#string

Jordi Berenguer

http://www.w3.org/2001/XMLSchema#string

Mercedes Barzi

http://www.w3.org/2001/XMLSchema#string

P2860

Selenoproteins.

Developmental neurotoxicity of industrial chemicals

Cell viability and proteomic analysis in cultured neurons exposed to methylmercury.

Prenatal methylmercury exposure hampers glutathione antioxidant system ontogenesis and causes long-lasting oxidative stress in the mouse brain.

The toxicology of mercury--current exposures and clinical manifestations.

Mice with a homozygous null mutation for the most abundant glutathione peroxidase, Gpx1, show increased susceptibility to the oxidative stress-inducing agents paraquat and hydrogen peroxide.

Inhibition of the human thioredoxin system. A molecular mechanism of mercury toxicity.

Involvement of glutamate and reactive oxygen species in methylmercury neurotoxicity.

Neurotoxicity of a polybrominated diphenyl ether mixture (DE-71) in mouse neurons and astrocytes is modulated by intracellular glutathione levels.

Catalase and glutathione peroxidase mimics.

P304

416-426

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1093/TOXSCI/KFP219

http://www.w3.org/2001/XMLSchema#string

P433

2

http://www.w3.org/2001/XMLSchema#string

P478

112

http://www.w3.org/2001/XMLSchema#string

P50

P577

2009-09-21T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P698

19770487

http://www.w3.org/2001/XMLSchema#string