Histone deacetylase inhibitor trichostatin A promotes the osteogenic differentiation of rat adipose-derived stem cells by altering the epigenetic modifications on Runx2 promoter in a BMP signaling-dependent manner.

Histone deacetylase inhibitor trichostatin A promotes the osteogenic differentiation of rat adipose-derived stem cells by altering the epigenetic modifications on Runx2 promoter in a BMP signaling-dependent manner.

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http://www.wikidata.org/entity/Q43421714
Epigenetic pathways regulating bone homeostasis: potential targeting for intervention of skeletal disorders.Histone deacetylase inhibition destabilizes the multi-potent state of uncommitted adipose-derived mesenchymal stromal cellsDifferent tenogenic differentiation capacities of different mesenchymal stem cells in the presence of BMP-12.Epigenetic Mechanisms Regulating Mesenchymal Stem Cell Differentiation.Histone deacetylase inhibition promotes osteoblast maturation by altering the histone H4 epigenome and reduces Akt phosphorylation.Bone morphogenetic protein 9 (BMP9) induces effective bone formation from reversibly immortalized multipotent adipose-derived (iMAD) mesenchymal stem cells.KDM5A controls bone morphogenic protein 2-induced osteogenic differentiation of bone mesenchymal stem cells during osteoporosis.Ovarian cancer stem-like cells show induced translineage-differentiation capacity and are suppressed by alkaline phosphatase inhibitor.Realizing the potential of gene-based molecular therapies in bone repair.Histone deacetylase inhibitor sodium butyrate promotes the osteogenic differentiation of rat adipose-derived stem cells.Profiling of human epigenetic regulators using a semi-automated real-time qPCR platform validated by next generation sequencing.Histone deacetylases and their roles in mineralized tissue regenerationHistone Deacetylase Inhibitor Trichostatin a Promotes the Apoptosis of Osteosarcoma Cells through p53 Signaling Pathway Activation.Runt-Related Transcription Factor 2 Induction During Differentiation of Wharton's Jelly Mesenchymal Stem Cells to Osteoblasts Is Regulated by Jumonji AT-Rich Interactive Domain 1B Histone Demethylase.Engineering Lineage Potency and Plasticity of Stem Cells using Epigenetic Molecules
P2860

Histone deacetylase inhibitor trichostatin A promotes the osteogenic differentiation of rat adipose-derived stem cells by altering the epigenetic modifications on Runx2 promoter in a BMP signaling-dependent manner.

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http://www.wikidata.org/entity/Q43421714
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2012 nî lūn-bûn
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Histone deacetylase inhibitor ...... MP signaling-dependent manner.
@en
Histone deacetylase inhibitor ...... MP signaling-dependent manner.
@nl
type
label
Histone deacetylase inhibitor ...... MP signaling-dependent manner.
@en
Histone deacetylase inhibitor ...... MP signaling-dependent manner.
@nl
prefLabel
Histone deacetylase inhibitor ...... MP signaling-dependent manner.
@en
Histone deacetylase inhibitor ...... MP signaling-dependent manner.
@nl
P1433
P1476
P2093
P304
P31
P356
P433
P478
P577
P698
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P1476
Histone deacetylase inhibitor ...... MP signaling-dependent manner.
@en
P2093
P304
P31
P356
P433
P478
P577
P698