The N-methyl-D-aspartate antagonists CGS 19755 and CPP reduce ischemic brain damage in gerbils.
about
SK2 channels are neuroprotective for ischemia-induced neuronal cell deathRodent models of focal cerebral ischemia: procedural pitfalls and translational problemsThe AMPA antagonist ZK 200775 in patients with acute ischaemic stroke: a double-blind, multicentre, placebo-controlled safety and tolerability study.Advances in stroke therapyIschemia induces short- and long-term remodeling of synaptic activity in the hippocampus.Characterization of the binding of [3H]-CGS 19755: a novel N-methyl-D-aspartate antagonist with nanomolar affinity in rat brainNeuroprotection for ischemic stroke: two decades of success and failure.CGS 19755 (Selfotel): A Novel Neuroprotective Agent Against CNS Injury.Links between long-term potentiation and neuropathology. An hypothesis involving calcium-activated proteases.Ion channels involved in stroke.Evolving concepts about the role of acidosis in ischemic neuropathology.Normal and abnormal calcium homeostasis in neurons: a basis for the pathophysiology of traumatic and ischemic central nervous system injury.Changes in extracellular amino acids and spontaneous neuronal activity during ischemia and extended reflow in the CA1 of the rat hippocampus.The neuroprotective action of dizocilpine (MK-801) in the rat middle cerebral artery occlusion model of focal ischaemia.Extracellular acidic sulfur-containing amino acids and gamma-glutamyl peptides in global ischemia: postischemic recovery of neuronal activity is paralleled by a tetrodotoxin-sensitive increase in cysteine sulfinate in the CA1 of the rat hippocampus.In vivo distribution of CGS-19755 within brain in a model of focal cerebral ischemia.Correlation of CGS 19755 neuroprotection against in vitro excitotoxicity and focal cerebral ischemia.Changes in extracellular concentrations of glutamate, aspartate, glycine, dopamine, serotonin, and dopamine metabolites after transient global ischemia in the rabbit brain.mGluR1 antagonist decreases tyrosine phosphorylation of NMDA receptor and attenuates infarct size after transient focal cerebral ischemia.GSK-3β inhibitor TDZD-8 reduces neonatal hypoxic-ischemic brain injury in mice.Ethanol inhibits NMDA receptor-mediated excitotoxicity in rat primary neuronal cultures.Delayed treatment with YM90K, an AMPA receptor antagonist, protects against ischaemic damage after middle cerebral artery occlusion in rats.Enhanced calcium uptake by CA1 pyramidal cell dendrites in the postischemic phase despite subnormal evoked field potentials: excitatory amino acid receptor dependency and relationship to neuronal damage.Postischemic blockade of AMPA but not NMDA receptors mitigates neuronal damage in the rat brain following transient severe cerebral ischemia.The effects of a competitive NMDA receptor antagonist (CGS-19755) on cerebral blood flow and pH in focal ischemia.Regionally selective effects of NMDA receptor antagonists against ischemic brain damage in the gerbil.Protection Against N-methyl-D-aspartate Receptor-Mediated Neuronal Degeneration In Rat Brain by 7-chlorokynurenate and 3-amino-1-hydroxypyrrolid-2-one, Antagonists at The Allosteric Site for Glycine.
P2860
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P2860
The N-methyl-D-aspartate antagonists CGS 19755 and CPP reduce ischemic brain damage in gerbils.
description
1988 nî lūn-bûn
@nan
1988年の論文
@ja
1988年学术文章
@wuu
1988年学术文章
@zh
1988年学术文章
@zh-cn
1988年学术文章
@zh-hans
1988年学术文章
@zh-my
1988年学术文章
@zh-sg
1988年學術文章
@yue
1988年學術文章
@zh-hant
name
The N-methyl-D-aspartate antag ...... hemic brain damage in gerbils.
@en
The N-methyl-D-aspartate antag ...... hemic brain damage in gerbils.
@nl
type
label
The N-methyl-D-aspartate antag ...... hemic brain damage in gerbils.
@en
The N-methyl-D-aspartate antag ...... hemic brain damage in gerbils.
@nl
prefLabel
The N-methyl-D-aspartate antag ...... hemic brain damage in gerbils.
@en
The N-methyl-D-aspartate antag ...... hemic brain damage in gerbils.
@nl
P2093
P1433
P1476
The N-methyl-D-aspartate antag ...... hemic brain damage in gerbils.
@en
P2093
J M Liebman
P E Etienne
S C Gerhardt
P304
P356
10.1016/0006-8993(88)91522-3
P407
P577
1988-03-01T00:00:00Z