Mutant potassium channels with altered binding of charybdotoxin, a pore-blocking peptide inhibitor.
about
The genome of Mesobuthus martensii reveals a unique adaptation model of arthropodsIto channels are octomeric complexes with four subunits of each Kv4.2 and K+ channel-interacting protein 2Cloning and expression of a human voltage-gated potassium channel. A novel member of the RCK potassium channel familyBrownian dynamics simulations of interaction between scorpion toxin Lq2 and potassium ion channel.Bacillus thuringiensis and its pesticidal crystal proteinsMolecular basis of altered excitability in Shaker mutants of Drosophila melanogasterSolution structure of GxTX-1E, a high-affinity tarantula toxin interacting with voltage sensors in Kv2.1 potassium channelsVitamin A Transport Mechanism of the Multitransmembrane Cell-Surface Receptor STRA6Structure of a pore-blocking toxin in complex with a eukaryotic voltage-dependent K + channelModeling the structure of agitoxin in complex with the Shaker K+ channel: a computational approach based on experimental distance restraints extracted from thermodynamic mutant cyclesCharacterization of a Shaw-related potassium channel family in rat brainVitamin A transport and the transmembrane pore in the cell-surface receptor for plasma retinol binding proteinThe pore-lining region of shaker voltage-gated potassium channels: comparison of beta-barrel and alpha-helix bundle modelsIs a beta-barrel model of the K+ channel energetically feasible?Determinants within the turret and pore-loop domains of KCNQ3 K+ channels governing functional activity.Purification, characterization and biosynthesis of parabutoxin 3, a component of Parabuthus transvaalicus venom.Charged residues in the M2 region of alpha-hENaC play a role in channel conductance.Sodium channel selectivity filter regulates antiarrhythmic drug bindingAlternative Shaker transcripts express either rapidly inactivating or noninactivating K+ channels.Identification of a phenylalkylamine binding region within the alpha 1 subunit of skeletal muscle Ca2+ channelsAtomic distance estimates from disulfides and high-affinity metal-binding sites in a K+ channel pore.An ERG channel inhibitor from the scorpion Buthus eupeus.Contributions of a negatively charged residue in the hydrophobic domain of the IRK1 inwardly rectifying K+ channel to K(+)-selective permeation.Mechanism of charybdotoxin block of a voltage-gated K+ channel.Hydrophobic mutations alter the movement of Mg2+ in the pore of voltage-gated potassium channels.Glutamate substitution in repeat IV alters divalent and monovalent cation permeation in the heart Ca2+ channel.A single nonpolar residue in the deep pore of related K+ channels acts as a K+:Rb+ conductance switchMapping the receptor site for ergtoxin, a specific blocker of ERG channels.Mutations in the K+ channel signature sequence.Interactions of the H5 pore region and hydroxylamine with N-type inactivation in the Shaker K+ channelFunctional role of a conserved aspartate in the external mouth of voltage-gated potassium channelsPrimary structure and properties of helothermine, a peptide toxin that blocks ryanodine receptors.A permanent ion binding site located between two gates of the Shaker K+ channel.Dequalinium: a novel, high-affinity blocker of CNGA1 channelsBeKm-1 is a HERG-specific toxin that shares the structure with ChTx but the mechanism of action with ErgTx1A subfamily of acidic alpha-K(+) toxins.Toxin-induced conformational changes in a potassium channel revealed by solid-state NMR.Tarantula toxins interacting with voltage sensors in potassium channels.The viral potassium channel Kcv: structural and functional features.Tarantula toxins use common surfaces for interacting with Kv and ASIC ion channels.
P2860
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P2860
Mutant potassium channels with altered binding of charybdotoxin, a pore-blocking peptide inhibitor.
description
1989 nî lūn-bûn
@nan
1989年の論文
@ja
1989年学术文章
@wuu
1989年学术文章
@zh
1989年学术文章
@zh-cn
1989年学术文章
@zh-hans
1989年学术文章
@zh-my
1989年学术文章
@zh-sg
1989年學術文章
@yue
1989年學術文章
@zh-hant
name
Mutant potassium channels with ...... re-blocking peptide inhibitor.
@en
Mutant potassium channels with ...... re-blocking peptide inhibitor.
@nl
type
label
Mutant potassium channels with ...... re-blocking peptide inhibitor.
@en
Mutant potassium channels with ...... re-blocking peptide inhibitor.
@nl
prefLabel
Mutant potassium channels with ...... re-blocking peptide inhibitor.
@en
Mutant potassium channels with ...... re-blocking peptide inhibitor.
@nl
P356
P1433
P1476
Mutant potassium channels with ...... re-blocking peptide inhibitor.
@en
P2093
P304
P356
10.1126/SCIENCE.2476850
P407
P577
1989-09-01T00:00:00Z