A let-7 microRNA SNP in the KRAS 3'UTR is prognostic in early-stage colorectal cancer. - Wikidata - wikimedia - TriplyDB

A let-7 microRNA SNP in the KRAS 3'UTR is prognostic in early-stage colorectal cancer.

A let-7 microRNA SNP in the KRAS 3'UTR is prognostic in early-stage colorectal cancer.

http://www.wikidata.org/entity/Q43496062

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RAS-MAPK pathway epigenetic activation in cancer: miRNAs in action MicroRNAs as growth regulators, their function and biomarker status in colorectal cancer Non-coding landscapes of colorectal cancer Let-7 microRNA-binding-site polymorphism in the 3'UTR of KRAS and colorectal cancer outcome: a systematic review and meta-analysis Association between SNPs in Serpin gene family and risk of esophageal squamous cell carcinoma.SNPs in microRNA binding sites as prognostic and predictive cancer biomarkers Association study of the let-7 miRNA-complementary site variant in the 3' untranslated region of the KRAS gene in stage III colon cancer (NCCTG N0147 Clinical Trial).MicroRNA binding site polymorphisms as biomarkers in cancer management and research.A let-7 microRNA-binding site polymorphism in KRAS predicts improved outcome in patients with metastatic colorectal cancer treated with salvage cetuximab/panitumumab monotherapy.MicroRNA-5p and -3p co-expression and cross-targeting in colon cancer cells.Let-7 miRNA-binding site polymorphism in the KRAS 3'UTR; colorectal cancer screening population prevalence and influence on clinical outcome in patients with metastatic colorectal cancer treated with 5-fluorouracil and oxaliplatin +/- cetuximab The KRAS-variant and miRNA expression in RTOG endometrial cancer clinical trials 9708 and 9905 Effect of a common genetic variant microRNA-146a rs2910164 on colorectal cancer: a meta-analysis.RETRACTED: Increased Ras GTPase activity is regulated by miRNAs that can be attenuated by CDF treatment in pancreatic cancer cells.Prognostic role of the LCS6 KRAS variant in locally advanced rectal cancer: results of the EXPERT-C trial.The role of microRNAs in colorectal cancer.Role of KRAS-LCS6 polymorphism in advanced NSCLC patients treated with erlotinib or docetaxel in second line treatment (TAILOR)KRAS and VEGF gene 3'-UTR single nucleotide polymorphisms predicted susceptibility in colorectal cancer.Local microRNA delivery targets Palladin and prevents metastatic breast cancer.Genetic variation rs7930 in the miR-4273-5p target site is associated with a risk of colorectal cancer.Discovery and functional assessment of gene variants in the vascular endothelial growth factor pathway Extensive sequence variation in the 3' untranslated region of the KRAS gene in lung and ovarian cancer cases.MicroRNAs in colorectal cancer as markers and targets: Recent advances.MiRNAs and LincRNAs: Could they be considered as biomarkers in colorectal cancer?miRNA pharmacogenomics: the new frontier for personalized medicine in cancer?miRNAs and long noncoding RNAs as biomarkers in human diseases.MicroRNAs targeting EGFR signalling pathway in colorectal cancer.Anti-epidermal growth factor receptor therapy in head and neck squamous cell carcinoma: focus on potential molecular mechanisms of drug resistance The role of microRNA in castration-resistant prostate cancer.MicroRNA dysregulation as a prognostic biomarker in colorectal cancer Early detection of colorectal cancer: from conventional methods to novel biomarkers.Incorporating traditional and emerging biomarkers in the clinical management of metastatic colorectal cancer.Involvement of Non-coding RNAs in Chemo- and Radioresistance of Colorectal Cancer.Non-coding RNAs Enabling Prognostic Stratification and Prediction of Therapeutic Response in Colorectal Cancer Patients.Noncoding RNA and colorectal cancer: its epigenetic role.Polymorphisms in Non-coding RNA Genes and Their Targets Sites as Risk Factors of Sporadic Colorectal Cancer.Targeted knock-in of the polymorphism rs61764370 does not affect KRAS expression but reduces let-7 levels.The role of microRNAs in cancer susceptibility.Identification of a functional polymorphism affecting microRNA binding in the susceptibility locus 1q25.3 for colorectal cancer.KRAS polymorphisms are associated with survival of CRC in Chinese population.

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P2860

A let-7 microRNA SNP in the KRAS 3'UTR is prognostic in early-stage colorectal cancer.

http://www.wikidata.org/entity/Q43496062

description

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2011年学术文章

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2011年学术文章

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2011年学术文章

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2011年学术文章

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2011年學術文章

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2011年學術文章

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name

A let-7 microRNA SNP in the KRAS 3'UTR is prognostic in early-stage colorectal cancer.

@en

A let-7 microRNA SNP in the KRAS 3'UTR is prognostic in early-stage colorectal cancer.

@nl

type

label

A let-7 microRNA SNP in the KRAS 3'UTR is prognostic in early-stage colorectal cancer.

@en

A let-7 microRNA SNP in the KRAS 3'UTR is prognostic in early-stage colorectal cancer.

@nl

prefLabel

A let-7 microRNA SNP in the KRAS 3'UTR is prognostic in early-stage colorectal cancer.

@en

A let-7 microRNA SNP in the KRAS 3'UTR is prognostic in early-stage colorectal cancer.

@nl

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Clinical Cancer Research

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A let-7 microRNA SNP in the KRAS 3'UTR is prognostic in early-stage colorectal cancer.

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Fred T Bosman

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Kim A D Wouters

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Kim M Smits

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Leo J Schouten

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Matty P Weijenberg

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Sunitha Nallur

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Trupti Paranjape

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P2860

Human microRNA genes are frequently located at fragile sites and genomic regions involved in cancers

Microsatellite instability in colorectal cancer

Methylation-specific PCR: a novel PCR assay for methylation status of CpG islands

A let-7 microRNA-binding site polymorphism in the KRAS 3' UTR is associated with reduced survival in oral cancers

Suppression of non-small cell lung tumor development by the let-7 microRNA family

Enjoy the Silence: The Story of let-7 MicroRNA and Cancer

A SNP in a let-7 microRNA complementary site in the KRAS 3' untranslated region increases non-small cell lung cancer risk

RAS is regulated by the let-7 microRNA family

let-7 microRNA functions as a potential growth suppressor in human colon cancer cells

let-7 MicroRNA transfer in pancreatic cancer-derived cells inhibits in vitro cell proliferation but fails to alter tumor progression

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10.1158/1078-0432.CCR-11-0990

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24

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17

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Joanne B. Weidhaas

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21994416

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colorectal cancer

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5919188

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