The antihypertensive hydralazine is an efficient scavenger of acrolein.
about
Anti-acrolein treatment improves behavioral outcome and alleviates myelin damage in experimental autoimmune encephalomyelitis mouseMolecular mechanisms of acrolein-mediated myelin destruction in CNS trauma and diseaseAcrolein as a novel therapeutic target for motor and sensory deficits in spinal cord injuryHydralazine modifies Aβ fibril formation and prevents modification by lipids in vitro.Neuroprotective role of hydralazine in rat spinal cord injury-attenuation of acrolein-mediated damage.Detoxification of aldehydes by histidine-containing dipeptides: from chemistry to clinical implicationsAcrolein-mediated injury in nervous system trauma and diseasesLipoxidation-derived reactive carbonyl species as potential drug targets in preventing protein carbonylation and related cellular dysfunction.Intervention strategies to inhibit protein carbonylation by lipoxidation-derived reactive carbonyls.Advanced lipid peroxidation end products in oxidative damage to proteins. Potential role in diseases and therapeutic prospects for the inhibitors.Mitigation of sensory and motor deficits by acrolein scavenger phenelzine in a rat model of spinal cord contusive injuryGenetics and prospective therapeutic targets for Sjögren-Larsson Syndrome.Acrolein Is a Pathogenic Mediator of Alcoholic Liver Disease and the Scavenger Hydralazine Is Protective in MiceAcrolein scavenging: a potential novel mechanism of attenuating oxidative stress following spinal cord injury.Acrolein scavengers: reactivity, mechanism and impact on health.Therapeutic potential of targeting lipid aldehydes and lipoxidation end-products in the treatment of ocular disease.Regulation and therapeutic strategies of 4-hydroxy-2-nonenal metabolism in heart disease.Acrolein Scavenger Hydralazine Prevents Streptozotocin-Induced Painful Diabetic Neuropathy and Spinal Neuroinflammation in Rats.Computational approaches in the rational design of improved carbonyl quenchers: focus on histidine containing dipeptides.Critical role of acrolein in secondary injury following ex vivo spinal cord trauma.Hydralazine inhibits compression and acrolein-mediated injuries in ex vivo spinal cord.CONTINUOUS INFUSION OF PHENELZINE, CYCLOSPORINE A OR THE COMBINATION: EVALUATION OF MITOCHONDRIAL BIOENERGETICS, OXIDATIVE DAMAGE AND CYTOSKELETAL DEGRADATION FOLLOWING SEVERE CONTROLLED CORTICAL IMPACT TRAUMATIC BRAIN INJURY IN RATS.Dimercaprol is an acrolein scavenger that mitigates acrolein-mediated PC-12 cells toxicity and reduces acrolein in rat following spinal cord injury.Hydralazine rescues PC12 cells from acrolein-mediated death.Systemic Acrolein Elevations in Mice With Experimental Autoimmune Encephalomyelitis and Patients With Multiple Sclerosis.
P2860
Q24630119-700F5422-30C1-4303-890B-B05221DEF12CQ28081607-99FCC085-D8F5-4058-8E80-8115B272ED0EQ34096164-5459497D-57CC-4F42-8662-D857E535EAA4Q34549266-0E50BFC5-0BC4-4AE6-B9CD-8989A85DFCEFQ34657926-0AE090CB-05AD-42ED-9237-867D3F3B4B98Q35565861-90125AA1-C213-433C-BFFC-0C221E842CA1Q36452743-86070190-7294-47AE-A072-F31D1ADC1159Q36568547-B6698A57-5062-4C4B-9AB7-F6625E6D8F90Q36624650-EB2CE5F0-3843-47BB-A2A7-BA5295EAFBC4Q36887564-D806CD8E-A656-4165-B53F-ED2F0141350BQ37075227-76159C9B-7F81-4C70-8865-23DB814BA429Q37185656-90D6914E-E812-4D0C-A36A-EB0BB38527F7Q37297729-3153982C-F849-4FA0-BF35-F1765428044AQ37603404-E536CD6F-0617-48A8-8FF2-F8E6F3A3AFCCQ37895630-58D59765-7DE7-44E1-B847-5E5C57D3E855Q38077549-C85C845C-46BB-4560-93BF-236E40518B47Q38163001-71A4262C-DEF6-4F39-8C2C-9EDEABD6C7FDQ38734248-CFDB10E1-5D81-4D05-B328-5F56DAC5A420Q38825427-EBA4A6DB-CAA7-41F2-9A03-2A117DA2CE37Q41879134-E8002EA0-536B-4F04-BB8D-36D52EB13D04Q46905314-D2D35E3C-BC5B-405D-8848-533A0A87002BQ47656401-3FF3F271-B44F-4A13-AB31-8166BECC2F9DQ48116579-7B8557B1-7EC6-4C5E-86FB-71C223DC8E6CQ50480044-F1E0459B-FC6F-4A93-BEA0-BF164CA8579BQ55497030-E9FE892C-FBE6-48C3-9FAF-069E79DA6BAE
P2860
The antihypertensive hydralazine is an efficient scavenger of acrolein.
description
2000 nî lūn-bûn
@nan
2000年の論文
@ja
2000年学术文章
@wuu
2000年学术文章
@zh
2000年学术文章
@zh-cn
2000年学术文章
@zh-hans
2000年学术文章
@zh-my
2000年学术文章
@zh-sg
2000年學術文章
@yue
2000年學術文章
@zh-hant
name
The antihypertensive hydralazine is an efficient scavenger of acrolein.
@en
The antihypertensive hydralazine is an efficient scavenger of acrolein.
@nl
type
label
The antihypertensive hydralazine is an efficient scavenger of acrolein.
@en
The antihypertensive hydralazine is an efficient scavenger of acrolein.
@nl
prefLabel
The antihypertensive hydralazine is an efficient scavenger of acrolein.
@en
The antihypertensive hydralazine is an efficient scavenger of acrolein.
@nl
P2860
P356
P1433
P1476
The antihypertensive hydralazine is an efficient scavenger of acrolein
@en
P2093
Burcham PC
Fontaine F
P2860
P356
10.1179/RER.2000.5.1.47
P577
2000-01-01T00:00:00Z