A novel inhibitor-binding site on the HIV-1 capsid N-terminal domain leads to improved crystallization via compound-mediated dimerization.
about
Discovery of Novel Small-Molecule HIV-1 Replication Inhibitors That Stabilize Capsid ComplexesMxB binds to the HIV-1 core and prevents the uncoating process of HIV-1Structural insight into HIV-1 restriction by MxB.Identification of a small molecule HIV-1 inhibitor that targets the capsid hexamer.HIV-1 Capsid Inhibitors as Antiretroviral AgentsAllosteric modulation of protein oligomerization: an emerging approach to drug design.Inhibition of HIV-1 Maturation via Small-Molecule Targeting of the Amino-Terminal Domain in the Viral Capsid Protein.HIV-1 Capsid Stabilization Assay.Inhibitors of the HIV-1 capsid, a target of opportunity.
P2860
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P2860
A novel inhibitor-binding site on the HIV-1 capsid N-terminal domain leads to improved crystallization via compound-mediated dimerization.
description
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name
A novel inhibitor-binding site ...... ompound-mediated dimerization.
@en
A novel inhibitor-binding site ...... ompound-mediated dimerization.
@nl
type
label
A novel inhibitor-binding site ...... ompound-mediated dimerization.
@en
A novel inhibitor-binding site ...... ompound-mediated dimerization.
@nl
prefLabel
A novel inhibitor-binding site ...... ompound-mediated dimerization.
@en
A novel inhibitor-binding site ...... ompound-mediated dimerization.
@nl
P2093
P2860
P1476
A novel inhibitor-binding site ...... ompound-mediated dimerization.
@en
P2093
Anne Marie Faucher
Christopher T Lemke
Nathalie Goudreau
Pierre Bonneau
Stephen W Mason
Steve Titolo
P2860
P304
P356
10.1107/S0907444913006409
P577
2013-05-15T00:00:00Z