The novel HSP90 inhibitor STA-1474 exhibits biologic activity against osteosarcoma cell lines.
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Contribution of chaperones to STAT pathway signaling.Phase I evaluation of STA-1474, a prodrug of the novel HSP90 inhibitor ganetespib, in dogs with spontaneous cancerHuman Genetic Relevance and Potent Antitumor Activity of Heat Shock Protein 90 Inhibition in Canine Lung Adenocarcinoma Cell LinesGetting folded: chaperone proteins in muscle development, maintenance and disease.A selenosemicarbazone complex with copper efficiently down-regulates the 90-kDa heat shock protein HSP90AA1 and its client proteins in cancer cells.Immunohistochemical investigation of cell cycle and apoptosis regulators (survivin, β-catenin, p53, caspase 3) in canine appendicular osteosarcoma.Activity of the heat shock protein 90 inhibitor ganetespib in melanomaThe Wnt signaling pathway: implications for therapy in osteosarcoma.Proteomics: a strategy to understand the novel targets in protein misfolding and cancer therapy.Hsp90 molecular chaperone inhibitors: are we there yet?Ganetespib (STA-9090), a nongeldanamycin HSP90 inhibitor, has potent antitumor activity in in vitro and in vivo models of non-small cell lung cancer.A database of reaction monitoring mass spectrometry assays for elucidating therapeutic response in cancerHeat shock protein expression analysis in canine osteosarcoma reveals HSP60 as a potentially relevant therapeutic targetGene expression profiling of canine osteosarcoma reveals genes associated with short and long survival times.Pre-clinical efficacy of PU-H71, a novel HSP90 inhibitor, alone and in combination with bortezomib in Ewing sarcoma.Signal transducer and activator of transcription 3 (STAT3): a promising target for anticancer therapy.Recent updates on the development of ganetespib as a Hsp90 inhibitor.Contributions of co-chaperones and post-translational modifications towards Hsp90 drug sensitivity.Canine osteosarcoma: a naturally occurring disease to inform pediatric oncology.Proteomic identification of proteins differentially expressed following overexpression of hTERT (human telomerase reverse transcriptase) in cancer cells.17-AAG and Apoptosis, Autophagy, and Mitophagy in Canine Osteosarcoma Cell Lines.HSP90 inhibitors in the context of heat shock and the unfolded protein response: effects on a primary canine pulmonary adenocarcinoma cell line.Canine osteosarcoma cells exhibit resistance to aurora kinase inhibitors.Anti-tumor activity of the HSP90 inhibitor SNX-2112 in pediatric cancer cell lines.Heat shock protein expression in canine osteosarcoma.Adapting Secretory Proteostasis and Function Through the Unfolded Protein Response.The Biological Activities of Oleocanthal from a Molecular Perspective.DNAJC5 facilitates USP19-dependent unconventional secretion of misfolded cytosolic proteins.
P2860
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P2860
The novel HSP90 inhibitor STA-1474 exhibits biologic activity against osteosarcoma cell lines.
description
2009 nî lūn-bûn
@nan
2009年の論文
@ja
2009年学术文章
@wuu
2009年学术文章
@zh
2009年学术文章
@zh-cn
2009年学术文章
@zh-hans
2009年学术文章
@zh-my
2009年学术文章
@zh-sg
2009年學術文章
@yue
2009年學術文章
@zh-hant
name
The novel HSP90 inhibitor STA- ...... ainst osteosarcoma cell lines.
@en
The novel HSP90 inhibitor STA- ...... ainst osteosarcoma cell lines.
@nl
type
label
The novel HSP90 inhibitor STA- ...... ainst osteosarcoma cell lines.
@en
The novel HSP90 inhibitor STA- ...... ainst osteosarcoma cell lines.
@nl
prefLabel
The novel HSP90 inhibitor STA- ...... ainst osteosarcoma cell lines.
@en
The novel HSP90 inhibitor STA- ...... ainst osteosarcoma cell lines.
@nl
P2093
P356
P1476
The novel HSP90 inhibitor STA- ...... ainst osteosarcoma cell lines.
@en
P2093
Cheryl A London
James Barsoum
Jennifer K McCleese
Kevin P Foley
Misty D Bear
Robert M Mihalek
Stacey L Fossey
Weiwen Ying
P304
P356
10.1002/IJC.24660
P577
2009-12-01T00:00:00Z