Detection of scrapie-associated fibril (SAF) proteins using anti-SAF antibody in non-purified tissue preparations.
about
Neuropathological changes in scrapie and Alzheimer's disease are associated with increased expression of apolipoprotein E and cathepsin D in astrocytesIn vitro expression in eukaryotic cells of a prion protein gene cloned from scrapie-infected mouse brain.Opposite effects of dextran sulfate 500, the polyene antibiotic MS-8209, and Congo red on accumulation of the protease-resistant isoform of PrP in the spleens of mice inoculated intraperitoneally with the scrapie agent.Prions and blood products.Species specificity in the cell-free conversion of prion protein to protease-resistant forms: a model for the scrapie species barrierAntiserum to scrapie-associated fibril protein cross-reacts with Spiroplasma mirum fibril proteins.Preparation and characterization of antibodies against mouse prion protein (PrP) peptides.Immunohistochemical detection of prion protein in lymphoid tissues of sheep with natural scrapie.Molecular biology and transgenetics of prion diseases.Prion protein biosynthesis in scrapie-infected and uninfected neuroblastoma cells.Normal and scrapie-associated forms of prion protein differ in their sensitivities to phospholipase and proteases in intact neuroblastoma cells.Dissociation between transmissible spongiform encephalopathy (TSE) infectivity and proteinase K-resistant PrP(Sc) levels in peripheral tissue from a murine transgenic model of TSE disease.Immunological comparison of scrapie-associated fibrils isolated from animals infected with four different scrapie strains.Immunological analysis of host and agent effects on Creutzfeldt-Jakob disease and scrapie prion proteins.Analyses of frequency of infection, specific infectivity, and prion protein biosynthesis in scrapie-infected neuroblastoma cell clones.Antisera to scrapie-associated fibril protein and prion protein decorate scrapie-associated fibrilsMouse polyclonal and monoclonal antibody to scrapie-associated fibril proteins.Isolation of a cDNA clone encoding the leader peptide of prion protein and expression of the homologous gene in various tissues.Prion liposomes.Pathogenic mutations within the hydrophobic domain of the prion protein lead to the formation of protease-sensitive prion species with increased lethality.Abnormal isoform of prion protein accumulates in follicular dendritic cells in mice with Creutzfeldt-Jakob disease.The major polypeptide of scrapie-associated fibrils (SAF) has the same size, charge distribution and N-terminal protein sequence as predicted for the normal brain protein (PrP).Assessment of western immunoblotting for the confirmatory diagnosis of ovine scrapie and bovine spongiform encephalopathy (BSE).The sequential development of abnormal prion protein accumulation in mice with Creutzfeldt-Jakob disease.The role of helix 1 aspartates and salt bridges in the stability and conversion of prion protein.Immunohistochemical detection of prion protein in sheep with scrapie.Isolation of scrapie agent from the placenta of sheep with natural scrapie in Japan.
P2860
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P2860
Detection of scrapie-associated fibril (SAF) proteins using anti-SAF antibody in non-purified tissue preparations.
description
1986 nî lūn-bûn
@nan
1986年の論文
@ja
1986年学术文章
@wuu
1986年学术文章
@zh-cn
1986年学术文章
@zh-hans
1986年学术文章
@zh-my
1986年学术文章
@zh-sg
1986年學術文章
@yue
1986年學術文章
@zh
1986年學術文章
@zh-hant
name
Detection of scrapie-associate ...... -purified tissue preparations.
@en
Detection of scrapie-associated fibril
@nl
type
label
Detection of scrapie-associate ...... -purified tissue preparations.
@en
Detection of scrapie-associated fibril
@nl
prefLabel
Detection of scrapie-associate ...... -purified tissue preparations.
@en
Detection of scrapie-associated fibril
@nl
P2093
P1476
Detection of scrapie-associate ...... -purified tissue preparations.
@en
P2093
H M Wisniewski
M C Papini
N K Robakis
R J Kascsak
R Rubenstein
P304
P356
10.1099/0022-1317-67-4-671
P407
P478
67 ( Pt 4)
P577
1986-04-01T00:00:00Z