about
Structure-based methods for predicting target mutation-induced drug resistance and rational drug design to overcome the problemPredicting resistance mutations using protein design algorithmsMultiscale Modeling of Biological Functions: From Enzymes to Molecular Machines (Nobel Lecture)Absolute binding free energy calculations: on the accuracy of computational scoring of protein-ligand interactionsToward accurate screening in computer-aided enzyme design.Validating computer simulations of enantioselective catalysis; reproducing the large steric and entropic contributions in Candida Antarctica lipase BOn catalytic preorganization in oxyanion holes: highlighting the problems with the gas-phase modeling of oxyanion holes and illustrating the need for complete enzyme models.Protein design algorithms predict viable resistance to an experimental antifolateComputer-Aided Protein Directed Evolution: a Review of Web Servers, Databases and other Computational Tools for Protein EngineeringValidating the vitality strategy for fighting drug resistance.Towards quantitative computer-aided studies of enzymatic enantioselectivity: the case of Candida antarctica lipase A.On the relationship between folding and chemical landscapes in enzyme catalysisElectrostatics in proteins and protein-ligand complexes.Biomacromolecular 3D-QSAR to Decipher Molecular Herbicide Resistance in Acetohydroxyacid Synthases.The linear interaction energy method for the prediction of protein stability changes upon mutationA binding free energy decomposition approach for accurate calculations of the fidelity of DNA polymerases.Protein-protein docking and analysis reveal that two homologous bacterial adenylyl cyclase toxins interact with calmodulin differently.
P2860
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P2860
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年学术文章
@wuu
2008年学术文章
@zh-cn
2008年学术文章
@zh-hans
2008年学术文章
@zh-my
2008年学术文章
@zh-sg
2008年學術文章
@yue
2008年學術文章
@zh
2008年學術文章
@zh-hant
name
Predicting drug-resistant mutations of HIV protease.
@en
Predicting drug-resistant mutations of HIV protease.
@nl
type
label
Predicting drug-resistant mutations of HIV protease.
@en
Predicting drug-resistant mutations of HIV protease.
@nl
prefLabel
Predicting drug-resistant mutations of HIV protease.
@en
Predicting drug-resistant mutations of HIV protease.
@nl
P356
P1476
Predicting drug-resistant mutations of HIV protease.
@en
P304
P356
10.1002/ANIE.200704178
P407
P577
2008-01-01T00:00:00Z