Metabolites of haloperidol display preferential activity at sigma receptors compared to dopamine D-2 receptors.
about
Methylphenidate enhances NMDA-receptor response in medial prefrontal cortex via sigma-1 receptor: a novel mechanism for methylphenidate actionAn unambiguous assay for the cloned human sigma1 receptor reveals high affinity interactions with dopamine D4 receptor selective compounds and a distinct structure-affinity relationship for butyrophenonesDifferentiation of sigma ligand-activated receptor subtypes that modulate NMDA-evoked [3H]-noradrenaline release in rat hippocampal slicesPotent inhibition of CYP2D6 by haloperidol metabolites: stereoselective inhibition by reduced haloperidolPrototypical antipsychotic drugs protect hippocampal neuronal cultures against cell death induced by growth medium deprivation.Current hypotheses on sigma receptors and their physiological role: possible implications in psychiatry.Early development of sigma-receptor ligands.Reversible metabolism of drugs.A prototypical Sigma-1 receptor antagonist protects against brain ischemia.Antagonism by haloperidol and its metabolites of mechanical hypersensitivity induced by intraplantar capsaicin in mice: role of sigma-1 receptors.Pharmacology and therapeutic potential of sigma(1) receptor ligands.Identification of a new functional target of haloperidol metabolite: implications for a receptor-independent role of 3-(4-fluorobenzoyl) propionic acid.Novel Sigma-1 receptor antagonists: from opioids to small molecules: what is new?N-oleoyl-dopamine increases locomotor activity in the rat.Lactobacillus plantarum consumption increases PepT1-mediated amino acid absorption by enhancing protein kinase C activity in spontaneously colitic mice.The neuropsychology of schizophrenia: A perspective from neurobehavioral geneticsWhy don't preschizophrenic children have delusions and hallucinations?
P2860
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P2860
Metabolites of haloperidol display preferential activity at sigma receptors compared to dopamine D-2 receptors.
description
1990 nî lūn-bûn
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1990年の論文
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1990年学术文章
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1990年学术文章
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1990年学术文章
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1990年學術文章
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name
Metabolites of haloperidol dis ...... red to dopamine D-2 receptors.
@en
Metabolites of haloperidol dis ...... red to dopamine D-2 receptors.
@nl
type
label
Metabolites of haloperidol dis ...... red to dopamine D-2 receptors.
@en
Metabolites of haloperidol dis ...... red to dopamine D-2 receptors.
@nl
prefLabel
Metabolites of haloperidol dis ...... red to dopamine D-2 receptors.
@en
Metabolites of haloperidol dis ...... red to dopamine D-2 receptors.
@nl
P2093
P1476
Metabolites of haloperidol dis ...... red to dopamine D-2 receptors.
@en
P2093
P304
P356
10.1016/0014-2999(90)90260-D
P407
P577
1990-02-01T00:00:00Z