Identification and characterization of the genetic changes responsible for the characteristic smooth-to-rough morphotype alterations of clinically persistent Mycobacterium abscessus.
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A specific polymorphism in Mycobacterium tuberculosis H37Rv causes differential ESAT-6 expression and identifies WhiB6 as a novel ESX-1 componentHigh-throughput sequencing for the study of bacterial pathogen biologyComplete genome sequence and comparative genomic analysis of Mycobacterium massiliense JCM 15300 in the Mycobacterium abscessus group reveal a conserved genomic island MmGI-1 related to putative lipid metabolismMycobacterium abscessus phospholipase C expression is induced during coculture within amoebae and enhances M. abscessus virulence in mice.Mycobacterium abscessus morphotype comparison in a murine model.Clonal Diversification and Changes in Lipid Traits and Colony Morphology in Mycobacterium abscessus Clinical Isolates.High-throughput transcriptomics reveals common and strain-specific responses of human macrophages to infection with Mycobacterium abscessus Smooth and Rough variants.Subinhibitory Doses of Aminoglycoside Antibiotics Induce Changes in the Phenotype of Mycobacterium abscessus.Functional characterization of the Mycobacterium abscessus genome coupled with condition specific transcriptomics reveals conserved molecular strategies for host adaptation and persistenceMycobacteria Clumping Increase Their Capacity to Damage Macrophages.Mycobacterium abscessus-Induced Granuloma Formation Is Strictly Dependent on TNF Signaling and Neutrophil Trafficking.Resistance to Thiacetazone Derivatives Active against Mycobacterium abscessus Involves Mutations in the MmpL5 Transcriptional Repressor MAB_4384.Revisiting the role of phospholipases C in virulence and the lifecycle of Mycobacterium tuberculosis.Deletion of a dehydratase important for intracellular growth and cording renders rough Mycobacterium abscessus avirulentMgtC as a Host-Induced Factor and Vaccine Candidate against Mycobacterium abscessus Infection.The distinct fate of smooth and rough Mycobacterium abscessus variants inside macrophages.Mycobacterium massiliense induces inflammatory responses in macrophages through Toll-like receptor 2 and c-Jun N-terminal kinase.High-level relatedness among Mycobacterium abscessus subsp. massiliense strains from widely separated outbreaksMycobacterium abscessus cording prevents phagocytosis and promotes abscess formation.Mycobacterium tuberculosis evolutionary pathogenesis and its putative impact on drug development.Intrinsic rifamycin resistance of Mycobacterium abscessus is mediated by ADP-ribosyltransferase MAB_0591.Mycobacterium abscessus glycopeptidolipids inhibit macrophage apoptosis and bacterial spreading by targeting mitochondrial cyclophilin D.The role of hydrophobicity in tuberculosis evolution and pathogenicity.pks5-recombination-mediated surface remodelling in Mycobacterium tuberculosis emergence.Mycobacterium massiliense Type II genotype leads to higher level of colony forming units and TNF-α secretion from human monocytes than Type I genotype.Mechanistic insight into mycobacterial MmpL protein function.Lack of antimicrobial bactericidal activity in Mycobacterium abscessus.Aminoglycoside-modifying enzymes determine the innate susceptibility to aminoglycoside antibiotics in rapidly growing mycobacteria.Characterization of rough and smooth morphotypes of Mycobacterium abscessus isolates from clinical specimensIdentification of genes required for Mycobacterium abscessus growth in vivo with a prominent role of the ESX-4 locus.galK-based suicide vector mediated allelic exchange in Mycobacterium abscessus.Effect of β-lactamase production and β-lactam instability on MIC testing results for Mycobacterium abscessus.Mycobacterium abscessus Smooth And Rough Morpohotypes Form Antimicrobial-Tolerant Biofilm Phenotypes But Are Killed by Acetic Acid.The many lives of nontuberculous mycobacteria.Elucidation of Mycobacterium abscessus aminoglycoside and capreomycin resistance by targeted deletion of three putative resistance genes.Neutrophil killing of Mycobacterium abscessus by intra- and extracellular mechanisms.Glycopeptidolipids, a Double-Edged Sword of the Mycobacterium abscessus Complex.Efflux Pumps in Mycobacteria: Antimicrobial Resistance, Physiological Functions, and Role in PathogenicityUnexpected Genomic and Phenotypic Diversity of Mycobacterium africanum Lineage 5 Affects Drug Resistance, Protein Secretion, and ImmunogenicityHydroalcoholic Extract and Ethyl Acetate Fraction of Leaves Decrease the Inflammatory Response to Subsp.
P2860
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P2860
Identification and characterization of the genetic changes responsible for the characteristic smooth-to-rough morphotype alterations of clinically persistent Mycobacterium abscessus.
description
2013 nî lūn-bûn
@nan
2013年の論文
@ja
2013年学术文章
@wuu
2013年学术文章
@zh
2013年学术文章
@zh-cn
2013年学术文章
@zh-hans
2013年学术文章
@zh-my
2013年学术文章
@zh-sg
2013年學術文章
@yue
2013年學術文章
@zh-hant
name
Identification and characteriz ...... stent Mycobacterium abscessus.
@en
Identification and characteriz ...... stent Mycobacterium abscessus.
@nl
type
label
Identification and characteriz ...... stent Mycobacterium abscessus.
@en
Identification and characteriz ...... stent Mycobacterium abscessus.
@nl
prefLabel
Identification and characteriz ...... stent Mycobacterium abscessus.
@en
Identification and characteriz ...... stent Mycobacterium abscessus.
@nl
P2093
P2860
P50
P356
P1476
Identification and characteriz ...... stent Mycobacterium abscessus.
@en
P2093
Alexandre Pawlik
Amanda Lohan
Anne-Laure Roux
Christiane Bouchier
Fabien Le Chevalier
Guillaume Garnier
Guillaume Sapriel
Jean-Louis Gaillard
Jean-Yves Coppée
Kevin Conlon
P2860
P304
P356
10.1111/MMI.12387
P407
P577
2013-09-17T00:00:00Z