Cell cycle protein expression in vascular smooth muscle cells in vitro and in vivo is regulated through phosphatidylinositol 3-kinase and mammalian target of rapamycin.
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In-stent stenosis: pathology and implications for the development of drug eluting stentsS-phase kinase-associated protein-2 (Skp2) promotes vascular smooth muscle cell proliferation and neointima formation in vivoTarget of rapamycin (TOR): an integrator of nutrient and growth factor signals and coordinator of cell growth and cell cycle progressionApoptosis resistance downstream of eIF4E: posttranscriptional activation of an anti-apoptotic transcript carrying a consensus hairpin structure.Neointimal hyperplasia associated with synthetic hemodialysis grafts.Renal angiomyolipomas from patients with sporadic lymphangiomyomatosis contain both neoplastic and non-neoplastic vascular structures.Matrine inhibits vascular smooth muscle cell proliferation by modulating the expression of cell cycle regulatory genes.Rapamycin regulates endothelial cell migration through regulation of the cyclin-dependent kinase inhibitor p27Kip1.Decellularized tissue-engineered blood vessel as an arterial conduitAdventitial contributions of the extracellular signal-regulated kinase and Akt pathways to neointimal hyperplasia.Atorvastatin calcium inhibits phenotypic modulation of PDGF-BB-induced VSMCs via down-regulation the Akt signaling pathway.Rapamycin attenuates hypoxia-induced pulmonary vascular remodeling and right ventricular hypertrophy in micePigment epithelium-derived factor inhibits neointimal hyperplasia after vascular injury by blocking NADPH oxidase-mediated reactive oxygen species generation.Translational control in endothelial cells.TGF-β and Smad3 modulate PI3K/Akt signaling pathway in vascular smooth muscle cellsHerbal composition of Cinnamomum cassia, Pinus densiflora, Curcuma longa and Glycyrrhiza glabra prevents atherosclerosis by upregulating p27 (Kip1) expression.Anaplastic lymphoma kinase and its signalling molecules as novel targets in lymphoma therapy.Enhanced Rb/E2F and TSC/mTOR Pathways Induce Synergistic Inhibition in PDGF-Induced Proliferation in Vascular Smooth Muscle CellsCoupled down-regulation of mTOR and telomerase activity during fluorouracil-induced apoptosis of hepatocarcinoma cellsThe cell cycle: a critical therapeutic target to prevent vascular proliferative disease.Detecting DNA synthesis of neointimal formation after catheter balloon injury in GK and in Wistar rats: using 5-ethynyl-2'-deoxyuridine.Pioglitazone, a PPARγ agonist, attenuates PDGF-induced vascular smooth muscle cell proliferation through AMPK-dependent and AMPK-independent inhibition of mTOR/p70S6K and ERK signaling.Promoting vascular regeneration as an alternative to conventional angioplasty-based intervention.Rapamycin inhibits growth factor-induced cell cycle regulation in pancreatic beta cellsInhibition of mTOR attenuates store-operated Ca2+ entry in cells from endarterectomized tissues of patients with chronic thromboembolic pulmonary hypertension.Regulation of vascular smooth muscle proliferation by heparin: inhibition of cyclin-dependent kinase 2 activity by p27(kip1).Role of platelets as mediators that link inflammation and thrombosis in atherosclerosis.Long-term safety of drug-eluting stents.Resveratrol inhibits phenotype modulation by platelet derived growth factor-bb in rat aortic smooth muscle cells.Sulforaphane inhibits platelet-derived growth factor-induced vascular smooth muscle cell proliferation by targeting mTOR/p70S6kinase signaling independent of Nrf2 activation.Eukaryotic initiation factor 4E-binding protein 1 (4E-BP1): a master regulator of mRNA translation involved in tumorigenesis.Human bronchial smooth muscle cell lines show a hypertrophic phenotype typical of severe asthma.Phosphorylation of GATA-6 is required for vascular smooth muscle cell differentiation after mTORC1 inhibitionProangiogenic stimulation of bone marrow endothelium engages mTOR and is inhibited by simultaneous blockade of mTOR and NF-kappaB.Shear stress activates Akt during vascular smooth muscle cell reorientation.Activation of multiple signaling modules is critical in angiotensin IV-induced lung endothelial cell proliferation.SHIP-2 and PTEN are expressed and active in vascular smooth muscle cell nuclei, but only SHIP-2 is associated with nuclear speckles.The mTOR/p70 S6K1 pathway regulates vascular smooth muscle cell differentiation.Extracellular ATP-induced proliferation of adventitial fibroblasts requires phosphoinositide 3-kinase, Akt, mammalian target of rapamycin, and p70 S6 kinase signaling pathways.Strain-induced vascular endothelial cell proliferation requires PI3K-dependent mTOR-4E-BP1 signal pathway.
P2860
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P2860
Cell cycle protein expression in vascular smooth muscle cells in vitro and in vivo is regulated through phosphatidylinositol 3-kinase and mammalian target of rapamycin.
description
2001 nî lūn-bûn
@nan
2001年の論文
@ja
2001年学术文章
@wuu
2001年学术文章
@zh
2001年学术文章
@zh-cn
2001年学术文章
@zh-hans
2001年学术文章
@zh-my
2001年学术文章
@zh-sg
2001年學術文章
@yue
2001年學術文章
@zh-hant
name
Cell cycle protein expression ...... mammalian target of rapamycin.
@en
Cell cycle protein expression ...... mammalian target of rapamycin.
@nl
type
label
Cell cycle protein expression ...... mammalian target of rapamycin.
@en
Cell cycle protein expression ...... mammalian target of rapamycin.
@nl
prefLabel
Cell cycle protein expression ...... mammalian target of rapamycin.
@en
Cell cycle protein expression ...... mammalian target of rapamycin.
@nl
P2093
P356
P1476
Cell cycle protein expression ...... mammalian target of rapamycin.
@en
P2093
Braun-Dullaeus RC
von Der Leyen HE
P304
P356
10.1161/HQ0701.092104
P407
P577
2001-07-01T00:00:00Z