Overexpression of phosphatase of regenerating liver-3 in breast cancer: association with a poor clinical outcome.
about
Drosophila PRL-1 is a growth inhibitor that counteracts the function of the Src oncogeneMetastasis-associated phosphatase PRL-2 regulates tumor cell migration and invasion.Phosphatase of regenerating liver-3 localizes to cyto-membrane and is required for B16F1 melanoma cell metastasis in vitro and in vivoPhosphatase of regenerating liver: a novel target for cancer therapy.Phosphatase of regenerating liver-3 directly interacts with integrin β1 and regulates its phosphorylation at tyrosine 783Targeting protein tyrosine phosphatases for anticancer drug discovery.Poor prognosis of phosphatase of regenerating liver 3 expression in gastric cancer: a meta-analysis.Tissue-specific alterations of PRL-1 and PRL-2 expression in cancerOverexpression and involvement in migration by the metastasis-associated phosphatase PRL-3 in human myeloma cellsUpregulation of protein tyrosine phosphatase type IVA member 3 (PTP4A3/PRL-3) is associated with tumor differentiation and a poor prognosis in human hepatocellular carcinomaPRL-3 is essentially overexpressed in primary colorectal tumours and associates with tumour aggressiveness.Expression of phosphatase regenerating liver 3 is an independent prognostic indicator for gastric cancerPhosphatase of regenerating liver-3 inhibits invasiveness and proliferation in non-small cell lung cancer by regulating the epithelial-mesenchymal transition.Enzyme activity of phosphatase of regenerating liver is controlled by the redox environment and its C-terminal residues.PRL-3 promotes the motility, invasion, and metastasis of LoVo colon cancer cells through PRL-3-integrin beta1-ERK1/2 and-MMP2 signaling.Molecular mechanisms of the PRL phosphatases.Genome-wide functional genetic screen with the anticancer agent AMPI-109 identifies PRL-3 as an oncogenic driver in triple-negative breast cancers.Suppression of breast tumor growth by DNA vaccination against phosphatase of regenerating liver 3.Prognostic significance of high phosphatase of regenerating liver-3 expression in patients with gastric cancer who underwent curative gastrectomy.PRL‑3 increases the aggressive phenotype of prostate cancer cells in vitro and its expression correlates with high-grade prostate tumors in patients.Expression of phosphatase of regenerating liver (PRL)-3, is independently associated with biochemical failure, clinical failure and death in prostate cancer.Expression of PRL-3 regulates proliferation and invasion of breast cancer cells in vitro.Therapeutic Targeting of Oncogenic Tyrosine Phosphatases.PRL-3 promotes breast cancer progression by downregulating p14ARF-mediated p53 expression.Elevated phosphatase of regenerating liver 3 (PRL-3) promotes cytoskeleton reorganization, cell migration and invasion in endometrial stromal cells from endometrioma.Expression of phosphatase of regenerating liver-3 in squamous cell carcinoma of the cervix.Expression of oxidized protein tyrosine phosphatase and γH2AX predicts poor survival of gastric carcinoma patients
P2860
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P2860
Overexpression of phosphatase of regenerating liver-3 in breast cancer: association with a poor clinical outcome.
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年学术文章
@wuu
2006年学术文章
@zh
2006年学术文章
@zh-cn
2006年学术文章
@zh-hans
2006年学术文章
@zh-my
2006年学术文章
@zh-sg
2006年學術文章
@yue
2006年學術文章
@zh-hant
name
Overexpression of phosphatase ...... with a poor clinical outcome.
@en
Overexpression of phosphatase ...... with a poor clinical outcome.
@nl
type
label
Overexpression of phosphatase ...... with a poor clinical outcome.
@en
Overexpression of phosphatase ...... with a poor clinical outcome.
@nl
prefLabel
Overexpression of phosphatase ...... with a poor clinical outcome.
@en
Overexpression of phosphatase ...... with a poor clinical outcome.
@nl
P2093
P356
P1433
P1476
Overexpression of phosphatase ...... with a poor clinical outcome.
@en
P2093
P304
P356
10.1093/ANNONC/MDL159
P577
2006-07-27T00:00:00Z