A membrane-proximal basic domain and cysteine cluster in the C-terminal tail of CCR5 constitute a bipartite motif critical for cell surface expression.
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The human gonadotropin releasing hormone type I receptor is a functional intracellular GPCR expressed on the nuclear membraneVaccinia virus activation of CCR5 invokes tyrosine phosphorylation signaling events that support virus replicationCloning and characterization of the pheromone biosynthesis activating neuropeptide receptor from the silkmoth, Bombyx mori. Significance of the carboxyl terminus in receptor internalization.Fluorescence resonance energy transfer imaging reveals that chemokine-binding modulates heterodimers of CXCR4 and CCR5 receptors.Modulation of gut-specific mechanisms by chronic δ(9)-tetrahydrocannabinol administration in male rhesus macaques infected with simian immunodeficiency virus: a systems biology analysis.C-terminus of OX2R significantly affects downstream signaling pathwaysVariants of CCR5, which are permissive for HIV-1 infection, show distinct functional responses to CCL3, CCL4 and CCL5.Alpha2B-adrenergic receptor interaction with tubulin controls its transport from the endoplasmic reticulum to the cell surface.Two mechanisms for human immunodeficiency virus type 1 inhibition by N-terminal modifications of RANTESDistinct mechanisms of agonist-induced endocytosis for human chemokine receptors CCR5 and CXCR4HIV-1 Nef impairs heterotrimeric G-protein signaling by targeting Gα(i2) for degradation through ubiquitination.Functional analysis of the murine cytomegalovirus chemokine receptor homologue M33: ablation of constitutive signaling is associated with an attenuated phenotype in vivo.A single mutation in helix 8 enhances the angiotensin II type 1a receptor transport and signaling.Role of C-terminal membrane-proximal basic residues in cell surface trafficking of HIV coreceptor GPR15 proteinStructural analysis of the human cannabinoid receptor one carboxyl-terminus identifies two amphipathic helices.CD4-CCR5 interaction in intracellular compartments contributes to receptor expression at the cell surfaceHIV-1 Nef down-modulates C-C and C-X-C chemokine receptors via ubiquitin and ubiquitin-independent mechanismConformational HIV-1 envelope on particulate structures: a tool for chemokine coreceptor binding studies.Pathogenesis of primary sclerosing cholangitis.Structural Diversity in Conserved Regions Like the DRY-Motif among Viral 7TM Receptors-A Consequence of Evolutionary Pressure?Morphine stimulates nitric oxide release in human mitochondria.Reduced cell surface expression of CCR5 in CCR5Delta 32 heterozygotes is mediated by gene dosage, rather than by receptor sequestration.CCL5-CCR5-mediated apoptosis in T cells: Requirement for glycosaminoglycan binding and CCL5 aggregation.CXCL12 signaling is independent of Jak2 and Jak3.On the mechanism and significance of ligand-induced internalization of human neutrophil chemokine receptors CXCR1 and CXCR2.Constitutive signaling of the human cytomegalovirus-encoded receptor UL33 differs from that of its rat cytomegalovirus homolog R33 by promiscuous activation of G proteins of the Gq, Gi, and Gs classes.Surface expression and endocytosis of the human cytomegalovirus-encoded chemokine receptor US28 is regulated by agonist-independent phosphorylation.CXCR4/CCR5 down-modulation and chemotaxis are regulated by the proteasome pathway.Identification of a binding element for the cytoplasmic regulator FROUNT in the membrane-proximal C-terminal region of chemokine receptors CCR2 and CCR5.Regulation of C-C chemokine receptor 5 (CCR5) stability by Lys-197 and by transmembrane protein aptamers that target it for lysosomal degradation.
P2860
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P2860
A membrane-proximal basic domain and cysteine cluster in the C-terminal tail of CCR5 constitute a bipartite motif critical for cell surface expression.
description
2001 nî lūn-bûn
@nan
2001年の論文
@ja
2001年学术文章
@wuu
2001年学术文章
@zh
2001年学术文章
@zh-cn
2001年学术文章
@zh-hans
2001年学术文章
@zh-my
2001年学术文章
@zh-sg
2001年學術文章
@yue
2001年學術文章
@zh-hant
name
A membrane-proximal basic doma ...... l for cell surface expression.
@en
A membrane-proximal basic doma ...... l for cell surface expression.
@nl
type
label
A membrane-proximal basic doma ...... l for cell surface expression.
@en
A membrane-proximal basic doma ...... l for cell surface expression.
@nl
prefLabel
A membrane-proximal basic doma ...... l for cell surface expression.
@en
A membrane-proximal basic doma ...... l for cell surface expression.
@nl
P2093
P2860
P356
P1476
A membrane-proximal basic doma ...... l for cell surface expression.
@en
P2093
P2860
P304
40133-40145
P356
10.1074/JBC.M105722200
P407
P577
2001-08-20T00:00:00Z