The N-terminal region of Sgs1, which interacts with Top3, is required for complementation of MMS sensitivity and suppression of hyper-recombination in sgs1 disruptants.
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Domain mapping of Escherichia coli RecQ defines the roles of conserved N- and C-terminal regions in the RecQ familyEvidence that the S.cerevisiae Sgs1 protein facilitates recombinational repair of telomeres during senescence.High-resolution structure of the E.coli RecQ helicase catalytic coreRmi1, a member of the Sgs1-Top3 complex in budding yeast, contributes to sister chromatid cohesionAn essential DNA strand-exchange activity is conserved in the divergent N-termini of BLM orthologs.Dpb11, the budding yeast homolog of TopBP1, functions with the checkpoint clamp in recombination repairYeast Rmi1/Nce4 controls genome stability as a subunit of the Sgs1-Top3 complex.Role of Elg1 protein in double strand break repair.Sgs1 function in the repair of DNA replication intermediates is separable from its role in homologous recombinational repair.The roles of the Saccharomyces cerevisiae RecQ helicase SGS1 in meiotic genome surveillance.mcl1+, the Schizosaccharomyces pombe homologue of CTF4, is important for chromosome replication, cohesion, and segregation.The dissolution of double Holliday junctions.Sgs1 truncations induce genome rearrangements but suppress detrimental effects of BLM overexpression in Saccharomyces cerevisiae.Sit down, relax and unwind: structural insights into RecQ helicase mechanisms.RecQ helicases: suppressors of tumorigenesis and premature aging.Structure and function of RecQ DNA helicases.Resolution by unassisted Top3 points to template switch recombination intermediates during DNA replication.An aromatic-rich loop couples DNA binding and ATP hydrolysis in the PriA DNA helicase.RecQ helicases; at the crossroad of genome replication, repair, and recombination.Bloom helicase and DNA topoisomerase IIIalpha are involved in the dissolution of sister chromatids.Functional relation among RecQ family helicases RecQL1, RecQL5, and BLM in cell growth and sister chromatid exchange formation.Telomerase-associated protein 1, HSP90, and topoisomerase IIalpha associate directly with the BLM helicase in immortalized cells using ALT and modulate its helicase activity using telomeric DNA substrates.Mrc1 and Srs2 are major actors in the regulation of spontaneous crossover.Sgs1 regulates gene conversion tract lengths and crossovers independently of its helicase activity.Defining the roles of the N-terminal region and the helicase activity of RECQ4A in DNA repair and homologous recombination in Arabidopsis.Multimerization domains are associated with apparent strand exchange activity in BLM and WRN DNA helicases.Degradation of Mrc1 promotes recombination-mediated restart of stalled replication forks.Role of Blm and collaborating factors in recombination and survival following replication stress in Ustilago maydis.The genetic consequences of ablating helicase activity and the Top3 interaction domain of Sgs1.High-throughput creation and functional profiling of DNA sequence variant libraries using CRISPR-Cas9 in yeast
P2860
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P2860
The N-terminal region of Sgs1, which interacts with Top3, is required for complementation of MMS sensitivity and suppression of hyper-recombination in sgs1 disruptants.
description
2001 nî lūn-bûn
@nan
2001年の論文
@ja
2001年学术文章
@wuu
2001年学术文章
@zh
2001年学术文章
@zh-cn
2001年学术文章
@zh-hans
2001年学术文章
@zh-my
2001年学术文章
@zh-sg
2001年學術文章
@yue
2001年學術文章
@zh-hant
name
The N-terminal region of Sgs1, ...... mbination in sgs1 disruptants.
@en
The N-terminal region of Sgs1, ...... mbination in sgs1 disruptants.
@nl
type
label
The N-terminal region of Sgs1, ...... mbination in sgs1 disruptants.
@en
The N-terminal region of Sgs1, ...... mbination in sgs1 disruptants.
@nl
prefLabel
The N-terminal region of Sgs1, ...... mbination in sgs1 disruptants.
@en
The N-terminal region of Sgs1, ...... mbination in sgs1 disruptants.
@nl
P2093
P356
P1476
The N-terminal region of Sgs1, ...... mbination in sgs1 disruptants.
@en
P2093
P2888
P304
P356
10.1007/S004380100479
P577
2001-07-01T00:00:00Z