Akt1/PKBalpha is required for normal growth but dispensable for maintenance of glucose homeostasis in mice.
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Systematic Analysis Reveals Elongation Factor 2 and α-Enolase as Novel Interaction Partners of AKT253BP2S, interacting with insulin receptor substrates, modulates insulin signalingKinetic mechanism of AKT/PKB enzyme familyCardiac regulation by phosphoinositide 3-kinases and PTENVEGF stimulation of mitochondrial biogenesis: requirement of AKT3 kinaseIdentification of a proline-rich Akt substrate as a 14-3-3 binding partnerProtein kinase cascades in the regulation of cardiac hypertrophyEssential role of PDK1 in regulating cell size and development in miceA mosaic activating mutation in AKT1 associated with the Proteus syndromeDe novo germline and postzygotic mutations in AKT3, PIK3R2 and PIK3CA cause a spectrum of related megalencephaly syndromesmTOR signaling: at the crossroads of plasticity, memory and diseaseNuclear Akt interacts with B23/NPM and protects it from proteolytic cleavage, enhancing cell survivalAkt and CHIP coregulate tau degradation through coordinated interactionsSevere diabetes, age-dependent loss of adipose tissue, and mild growth deficiency in mice lacking Akt2/PKB betaLife with a single isoform of Akt: mice lacking Akt2 and Akt3 are viable but display impaired glucose homeostasis and growth deficienciesAkt1 in endothelial cell and angiogenesisErythropoietin stimulates phosphorylation and activation of GATA-1 via the PI3-kinase/AKT signaling pathwayAkt isoforms in vascular diseaseDiverse mechanisms of AKT pathway activation in human malignancyPI3K-AKT-mTOR-signaling and beyond: the complex network in gastroenteropancreatic neuroendocrine neoplasmsmTOR-dependent cell survival mechanismsRegulation of Akt signaling by sirtuins: its implication in cardiac hypertrophy and agingMolecular basis of physiological heart growth: fundamental concepts and new playersWortmannin reduces insulin signaling and death in seizure-prone Pcmt1-/- miceEvodiamine inhibits insulin-stimulated mTOR-S6K activation and IRS1 serine phosphorylation in adipocytes and improves glucose tolerance in obese/diabetic miceMutation of the PDK1 PH Domain Inhibits Protein Kinase B/Akt, Leading to Small Size and Insulin ResistanceThe critical role of Akt in cardiovascular functionInhibition of JNK by cellular stress- and tumor necrosis factor alpha-induced AKT2 through activation of the NF kappa B pathway in human epithelial CellsPTEN is a protein tyrosine phosphatase for IRS1mTOR signaling in tumorigenesisRole of PI3K, mTOR and Akt2 signalling in hepatic tumorigenesis via the control of PKM2 expressionHaploinsufficiency of akt1 prolongs the lifespan of micePI3K/PTEN signaling in angiogenesis and tumorigenesisOverexpression of Akt1 enhances adipogenesis and leads to lipoma formation in zebrafishRole for Akt3/protein kinase Bgamma in attainment of normal brain sizeMolecular and genetic studies imply Akt-mediated signaling promotes protein kinase CbetaII alternative splicing via phosphorylation of serine/arginine-rich splicing factor SRp40Neuregulin signaling on glucose transport in muscle cellsInpp5f is a polyphosphoinositide phosphatase that regulates cardiac hypertrophic responsivenessThe PI-3 kinase/Akt pathway and T cell activation: pleiotropic pathways downstream of PIP3Aging and the Mammalian regulatory triumvirate
P2860
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P2860
Akt1/PKBalpha is required for normal growth but dispensable for maintenance of glucose homeostasis in mice.
description
2001 nî lūn-bûn
@nan
2001年の論文
@ja
2001年学术文章
@wuu
2001年学术文章
@zh-cn
2001年学术文章
@zh-hans
2001年学术文章
@zh-my
2001年学术文章
@zh-sg
2001年學術文章
@yue
2001年學術文章
@zh
2001年學術文章
@zh-hant
name
Akt1/PKBalpha is required for ...... f glucose homeostasis in mice.
@en
Akt1/PKBalpha is required for ...... f glucose homeostasis in mice.
@nl
type
label
Akt1/PKBalpha is required for ...... f glucose homeostasis in mice.
@en
Akt1/PKBalpha is required for ...... f glucose homeostasis in mice.
@nl
prefLabel
Akt1/PKBalpha is required for ...... f glucose homeostasis in mice.
@en
Akt1/PKBalpha is required for ...... f glucose homeostasis in mice.
@nl
P2093
P356
P1476
Akt1/PKBalpha is required for ...... f glucose homeostasis in mice.
@en
P2093
P304
38349-38352
P356
10.1074/JBC.C100462200
P407
P577
2001-08-31T00:00:00Z