Determination of in vivo absorption, metabolism, and transport of drugs by the human intestinal wall and liver with a novel perfusion technique.
about
Predicting Drug Extraction in the Human Gut Wall: Assessing Contributions from Drug Metabolizing Enzymes and Transporter Proteins using Preclinical ModelsPrediction of human pharmacokinetics--gut-wall metabolism.Sucralose, a synthetic organochlorine sweetener: overview of biological issuesPaediatric pharmacokinetics: key considerations.Intestinal drug absorption and bioavailability: beyond involvement of single transport function.The use of biopharmaceutic classification of drugs in drug discovery and development: current status and future extension.The human intestinal cytochrome P450 "pie".Methods to evaluate biliary excretion of drugs in humans: an updated review.Intestinal permeability and its relevance for absorption and elimination.Population-based mechanistic prediction of oral drug absorptionHuman clearance prediction: shifting the paradigm.In vitro and in vivo small intestinal metabolism of CYP3A and UGT substrates in preclinical animals species and humans: species differences.In vitro-in vivo extrapolation (IVIVE) for predicting human intestinal absorption and first-pass elimination of drugs: principles and applications.Quantitative Prediction of Drug-Drug Interactions Involving Inhibitory Metabolites in Drug Development: How Can Physiologically Based Pharmacokinetic Modeling Help?A physiologically based pharmacokinetic model for chickens exposed to feed supplemented with monensin during their lifetime.Prediction of the extent and variation of grapefruit juice-drug interactions from the pharmacokinetic profile in the absence of grapefruit juice.Prediction of human pharmacokinetics--evaluation of methods for prediction of hepatic metabolic clearance.Gastrointestinal absorption and metabolism of hesperetin-7-O-rutinoside and hesperetin-7-O-glucoside in healthy humans.Preparation and characterization of rodent intestinal microsomes: comparative assessment of two methods.An in vitro examination of the impact of polyethylene glycol 400, Pluronic P85, and vitamin E d-alpha-tocopheryl polyethylene glycol 1000 succinate on P-glycoprotein efflux and enterocyte-based metabolism in excised rat intestine.Gefitinib-phenytoin interaction is not correlated with the C-erythromycin breath test in healthy male volunteersInfluence of rifampicin on the expression and function of human intestinal cytochrome P450 enzymes.
P2860
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P2860
Determination of in vivo absorption, metabolism, and transport of drugs by the human intestinal wall and liver with a novel perfusion technique.
description
2001 nî lūn-bûn
@nan
2001年の論文
@ja
2001年学术文章
@wuu
2001年学术文章
@zh-cn
2001年学术文章
@zh-hans
2001年学术文章
@zh-my
2001年学术文章
@zh-sg
2001年學術文章
@yue
2001年學術文章
@zh
2001年學術文章
@zh-hant
name
Determination of in vivo absor ...... h a novel perfusion technique.
@en
Determination of in vivo absor ...... h a novel perfusion technique.
@nl
type
label
Determination of in vivo absor ...... h a novel perfusion technique.
@en
Determination of in vivo absor ...... h a novel perfusion technique.
@nl
prefLabel
Determination of in vivo absor ...... h a novel perfusion technique.
@en
Determination of in vivo absor ...... h a novel perfusion technique.
@nl
P2093
P356
P1476
Determination of in vivo absor ...... th a novel perfusion technique
@en
P2093
Eichelbaum M
Somogyi AA
von Richter O
P304
P356
10.1067/MCP.2001.117937
P407
P577
2001-09-01T00:00:00Z