Probing the effects of membrane cholesterol in the Torpedo californica acetylcholine receptor and the novel lipid-exposed mutation alpha C418W in Xenopus oocytes.
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Fatty Acid Regulation of Voltage- and Ligand-Gated Ion Channel FunctionA predicted binding site for cholesterol on the GABAA receptorMembrane Protein Structure, Function, and Dynamics: a Perspective from Experiments and Theory.Assessment of the functionality and stability of detergent purified nAChR from Torpedo using lipidic matrixes and macroscopic electrophysiology.Is there a preferential interaction between cholesterol and tryptophan residues in membrane proteins?Thermodynamics of heat activation of single capsaicin ion channels VR1.Cholesterol sensitivity of KIR2.1 is controlled by a belt of residues around the cytosolic pore.A long QT mutation substitutes cholesterol for phosphatidylinositol-4,5-bisphosphate in KCNQ1 channel regulation.Potential role of caveolin-1-positive domains in the regulation of the acetylcholine receptor's activatable pool: implications in the pathogenesis of a novel congenital myasthenic syndromeLateral diffusion, function, and expression of the slow channel congenital myasthenia syndrome αC418W nicotinic receptor mutation with changes in lipid raft components.Distant cytosolic residues mediate a two-way molecular switch that controls the modulation of inwardly rectifying potassium (Kir) channels by cholesterol and phosphatidylinositol 4,5-bisphosphate (PI(4,5)P(2)).Conformation-dependent hydrophobic photolabeling of the nicotinic receptor: electrophysiology-coordinated photochemistry and mass spectrometryTryptophan scanning of the acetylcholine receptor's betaM4 transmembrane domain: decoding allosteric linkage at the lipid-protein interface with ion-channel gating.Renal Na+-K+-Cl- cotransporter activity and vasopressin-induced trafficking are lipid raft-dependent.Identification of novel cholesterol-binding regions in Kir2 channels.Transgenic mouse model reveals an unsuspected role of the acetylcholine receptor in statin-induced neuromuscular adverse drug reactions.Cholesterol sensitivity of KIR2.1 depends on functional inter-links between the N and C termini.Structural Stringency of Cholesterol for Membrane Protein Function Utilizing Stereoisomers as Novel Tools: A Review.Cholesterol depletion activates rapid internalization of submicron-sized acetylcholine receptor domains at the cell membrane.TRPV1 is a novel target for omega-3 polyunsaturated fatty acids.A novel mechanism of modulation of 5-HT₃A receptors by hydrocortisone.Tryptophan scanning mutagenesis reveals distortions in the helical structure of the δM4 transmembrane domain of the Torpedo californica nicotinic acetylcholine receptor.Heterogeneous Inhibition in Macroscopic Current Responses of Four Nicotinic Acetylcholine Receptor Subtypes by Cholesterol Enrichment.Tryptophan-scanning mutagenesis in the alphaM3 transmembrane domain of the muscle-type acetylcholine receptor. A spring model revealed.Fluorescence and molecular dynamics studies of the acetylcholine receptor gammaM4 transmembrane peptide in reconstituted systems.Cholesterol up-regulates neuronal G protein-gated inwardly rectifying potassium (GIRK) channel activity in the hippocampus.An allosteric link connecting the lipid-protein interface to the gating of the nicotinic acetylcholine receptor.
P2860
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P2860
Probing the effects of membrane cholesterol in the Torpedo californica acetylcholine receptor and the novel lipid-exposed mutation alpha C418W in Xenopus oocytes.
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2001 nî lūn-bûn
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2001年の論文
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2001年学术文章
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2001年学术文章
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2001年学术文章
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2001年学术文章
@zh-hans
2001年学术文章
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2001年學術文章
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name
Probing the effects of membran ...... lpha C418W in Xenopus oocytes.
@en
Probing the effects of membran ...... lpha C418W in Xenopus oocytes.
@nl
type
label
Probing the effects of membran ...... lpha C418W in Xenopus oocytes.
@en
Probing the effects of membran ...... lpha C418W in Xenopus oocytes.
@nl
prefLabel
Probing the effects of membran ...... lpha C418W in Xenopus oocytes.
@en
Probing the effects of membran ...... lpha C418W in Xenopus oocytes.
@nl
P2093
P2860
P356
P1476
Probing the effects of membran ...... lpha C418W in Xenopus oocytes.
@en
P2093
Asmar-Rovira GA
Lasalde-Dominicci JA
Santiago J
P2860
P304
46523-46532
P356
10.1074/JBC.M104563200
P407
P577
2001-09-20T00:00:00Z