Redox homeostasis modulates the sensitivity of myeloma cells to bortezomib.
about
Stress Regulates Aquaporin-8 Permeability to Impact Cell Growth and Survival.Trial Watch: Proteasomal inhibitors for anticancer therapyEx-vivo dynamic 3-D culture of human tissues in the RCCS™ bioreactor allows the study of Multiple Myeloma biology and response to therapyTargeting MUC1-C is synergistic with bortezomib in downregulating TIGAR and inducing ROS-mediated myeloma cell death.Oxidative stress by targeted agents promotes cytotoxicity in hematologic malignancies.Phase 2 study of imexon, a prooxidant molecule, in relapsed and refractory B-cell non-Hodgkin lymphomaCopper-zinc superoxide dismutase-mediated redox regulation of bortezomib resistance in multiple myeloma.Treatment-induced oxidative stress and cellular antioxidant capacity determine response to bortezomib in mantle cell lymphoma.Drug metabolism and clearance system in tumor cells of patients with multiple myelomaIron increases the susceptibility of multiple myeloma cells to bortezomib.Antioxidant protection: A promising therapeutic intervention in neurodegenerative disease.Manipulation of cellular redox parameters for improving therapeutic responses in B-cell lymphoma and multiple myeloma.Sabotaging of the oxidative stress response by an oncogenic noncoding RNA.Cyclin D1 unbalances the redox status controlling cell adhesion, migration, and drug resistance in myeloma cells.TrxR1 inhibition overcomes both hypoxia-induced and acquired bortezomib resistance in multiple myeloma through NF-кβ inhibition.Inhibition of thioredoxin 1 leads to apoptosis in drug-resistant multiple myelomaBortezomib action in multiple myeloma: microRNA-mediated synergy (and miR-27a/CDK5 driven sensitivity)?Intracellular glutathione determines bortezomib cytotoxicity in multiple myeloma cells.The Multifaceted Roles of DJ-1 as an Antioxidant.Repurposing of the CDK inhibitor PHA-767491 as a NRF2 inhibitor drug candidate for cancer therapy via redox modulation.Targeted knockdown of DJ-1 induces multiple myeloma cell death via KLF6 upregulation.Modeling Multiple Myeloma-Bone Marrow interactions and response to drugs in a 3D surrogate microenvironment.Resveratrol Sensitizes Carfilzomib-Induced Apoptosis via Promoting Oxidative Stress in Multiple Myeloma Cells.
P2860
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P2860
Redox homeostasis modulates the sensitivity of myeloma cells to bortezomib.
description
2008 nî lūn-bûn
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2008年の論文
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2008年学术文章
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2008年学术文章
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2008年学术文章
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2008年学术文章
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2008年學術文章
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name
Redox homeostasis modulates the sensitivity of myeloma cells to bortezomib.
@en
Redox homeostasis modulates the sensitivity of myeloma cells to bortezomib.
@nl
type
label
Redox homeostasis modulates the sensitivity of myeloma cells to bortezomib.
@en
Redox homeostasis modulates the sensitivity of myeloma cells to bortezomib.
@nl
prefLabel
Redox homeostasis modulates the sensitivity of myeloma cells to bortezomib.
@en
Redox homeostasis modulates the sensitivity of myeloma cells to bortezomib.
@nl
P2093
P1476
Redox homeostasis modulates the sensitivity of myeloma cells to bortezomib.
@en
P2093
Federico Caligaris-Cappio
Sara Cozza
Silvia Nerini-Molteni
P304
P356
10.1111/J.1365-2141.2008.07066.X
P407
P577
2008-03-12T00:00:00Z