Comparison of the phenotype of NK1R-/- mice with pharmacological blockade of the substance P (NK1 ) receptor in assays for antidepressant and anxiolytic drugs.
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Biological and Pharmacological Aspects of the NK1-ReceptorGalanin receptor antagonists : a potential novel pharmacological treatment for mood disordersNew approaches to antidepressant drug discovery: beyond monoaminesThe autism diagnosis in translation: shared affect in children and mouse models of ASD.Translating mouse vocalizations: prosody and frequency modulationAnxiolytic-like effects of the neurokinin 1 receptor antagonist GR-205171 in the elevated plus maze and contextual fear-potentiated startle model of anxiety in gerbils.Translating the neuroscience of alcoholism into clinical treatments: from blocking the buzz to curing the blues.The role of substance P in stress and anxiety responses.New insights into the antidepressant actions of substance P (NK1 receptor) antagonists.Substance P and Substance P receptor antagonists in the pathogenesis and treatment of affective disorders.In search of a depressed mouse: utility of models for studying depression-related behavior in genetically modified mice.Substance P receptor antagonists in psychiatry: rationale for development and therapeutic potential.Involvement of substance P and the NK-1 receptor in human pathology.Behavioral and pharmacological validation of the gerbil forced-swim test: effects of neurokinin-1 receptor antagonists.[3H]GR205171 displays similar NK1 receptor binding profile in gerbil and human brain.Translational and reverse translational research on the role of stress in drug craving and relapse.Mechanisms of selection mediated by interleukin-7, the preBCR, and hemokinin-1 during B-cell development.Potentiation of brain stimulation reward by morphine: effects of neurokinin-1 receptor antagonism.Tracking the impact of translational research in psychiatry: state of the art and perspectivesAssessing the neuronal serotonergic target-based antidepressant stratagem: impact of in vivo interaction studies and knockout modelsRegulated norepinephrine transporter interaction with the neurokinin-1 receptor establishes transporter subcellular localization.The neurokinin-1 receptor modulates the methamphetamine-induced striatal apoptosis and nitric oxide formation in mice.Neuropeptide and sigma receptors as novel therapeutic targets for the pharmacotherapy of depression.Decreased Prostaglandin D2 Levels in Major Depressive Disorder Are Associated with Depression-Like Behaviors.The behavioural response of mice lacking NK₁ receptors to guanfacine resembles its clinical profile in treatment of ADHD.Blockade of substance P (neurokinin 1) receptors enhances extracellular serotonin when combined with a selective serotonin reuptake inhibitor: an in vivo microdialysis study in mice.Changes in signaling pathways regulating neuroplasticity induced by neurokinin 1 receptor knockout.Blockade of tachykinin NK1 receptors attenuates stress-induced rise of extracellular noradrenaline and dopamine in the rat and gerbil medial prefrontal cortex.Genetic background influences the behavioural and molecular consequences of neurokinin-1 receptor knockout.Neurokinin-1 receptors (NK1R:s), alcohol consumption, and alcohol reward in mice.Increased neurogenesis and brain-derived neurotrophic factor in neurokinin-1 receptor gene knockout mice.Species differences in tachykinin receptor distribution: further evidence that the substance P (NK1) receptor predominates in human brain.Neurokinin1 antagonists potentiate antidepressant properties of serotonin reuptake inhibitors, yet blunt their anxiogenic actions: a neurochemical, electrophysiological, and behavioral characterization.Down-regulation of amygdala preprotachykinin A mRNA but not 3H-SP receptor binding sites in subjects affected by mood disorders and schizophrenia.Chronic psychosocial stress in tree shrews: effect of the substance P (NK1 receptor) antagonist L-760735 and clomipramine on endocrine and behavioral parameters.Antidepressant-like effects of agomelatine, melatonin and the NK1 receptor antagonist GR205171 in impulsive-related behaviour in rats.Neurokinin 1 receptor antagonism promotes active stress coping via enhanced septal 5-HT transmission.Lithium chloride regulation of the substance P encoding preprotachykinin a, Tac1 gene in rat hippocampal primary cells.Disruption of noradrenergic transmission and the behavioural response to a novel environment in NK1R-/- mice.Stereoselective and region-specific induction of immediate early gene expression in rat parietal cortex by blockade of neurokinin 1 receptors.
P2860
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P2860
Comparison of the phenotype of NK1R-/- mice with pharmacological blockade of the substance P (NK1 ) receptor in assays for antidepressant and anxiolytic drugs.
description
2001 nî lūn-bûn
@nan
2001年の論文
@ja
2001年学术文章
@wuu
2001年学术文章
@zh
2001年学术文章
@zh-cn
2001年学术文章
@zh-hans
2001年学术文章
@zh-my
2001年学术文章
@zh-sg
2001年學術文章
@yue
2001年學術文章
@zh-hant
name
Comparison of the phenotype of ...... pressant and anxiolytic drugs.
@en
Comparison of the phenotype of ...... al blockade of the substance P
@nl
type
label
Comparison of the phenotype of ...... pressant and anxiolytic drugs.
@en
Comparison of the phenotype of ...... al blockade of the substance P
@nl
prefLabel
Comparison of the phenotype of ...... pressant and anxiolytic drugs.
@en
Comparison of the phenotype of ...... al blockade of the substance P
@nl
P2093
P1476
Comparison of the phenotype of ...... pressant and anxiolytic drugs.
@en
P2093
A Wheeldon
C de Felipe
E J Carlson
N M Rupniak
R D Porsolt
T Harrison
P304
P356
10.1097/00008877-200111000-00011
P577
2001-11-01T00:00:00Z