Design and synthesis of pyrrolidine-5,5-trans-lactams (5-oxohexahydropyrrolo[3,2-b]pyrroles) as novel mechanism-based inhibitors of human cytomegalovirus protease. 2. Potency and chirality.
about
Current and potential treatments for ubiquitous but neglected herpesvirus infectionsBinding of small molecules to an adaptive protein-protein interfaceEnzyme Inhibition by Allosteric Capture of an Inactive ConformationBroad-Spectrum Allosteric Inhibition of Herpesvirus ProteasesSmall-molecule inhibitors of protein-protein interactions: progressing towards the dreamInhibition of a viral enzyme by a small-molecule dimer disruptor.A screening strategy for trapping the inactive conformer of a dimeric enzyme with a small molecule inhibitor.Ammonia synthons for the multicomponent assembly of complex gamma-lactams.Sulfonamide derivatives with protease inhibitory action as anticancer, anti-inflammatory and antiviral agents
P2860
Q27023452-1ED75B2A-E8F1-455F-9C92-77F953960120Q27640488-0A2BFE59-0FB4-40F3-8E8B-0B629B79F0B6Q27670647-E3BF5A5E-5895-47AA-A819-855EDF465D62Q27684483-E22DFAD3-C20D-445C-A5C8-440EA693D6CAQ29617758-C04FB28D-BCAD-4F10-87C3-287E4DA1BAF1Q33487129-613F6E87-A5D0-43F6-AD61-6695D3AF66E3Q34407579-D5C1349C-26B3-4BE6-A66A-9F6FD212D29AQ34881042-5A84AD4C-1892-4612-8ECD-2940EDDADCFEQ58863308-0D438C4B-DDFB-498E-8D88-EA629DAF8CFC
P2860
Design and synthesis of pyrrolidine-5,5-trans-lactams (5-oxohexahydropyrrolo[3,2-b]pyrroles) as novel mechanism-based inhibitors of human cytomegalovirus protease. 2. Potency and chirality.
description
2002 nî lūn-bûn
@nan
2002年の論文
@ja
2002年学术文章
@wuu
2002年学术文章
@zh
2002年学术文章
@zh-cn
2002年学术文章
@zh-hans
2002年学术文章
@zh-my
2002年学术文章
@zh-sg
2002年學術文章
@yue
2002年學術文章
@zh-hant
name
Design and synthesis of pyrrol ...... ase. 2. Potency and chirality.
@en
Design and synthesis of pyrrol ...... ase. 2. Potency and chirality.
@nl
type
label
Design and synthesis of pyrrol ...... ase. 2. Potency and chirality.
@en
Design and synthesis of pyrrol ...... ase. 2. Potency and chirality.
@nl
prefLabel
Design and synthesis of pyrrol ...... ase. 2. Potency and chirality.
@en
Design and synthesis of pyrrol ...... ase. 2. Potency and chirality.
@nl
P2093
P356
P1476
Design and synthesis of pyrrol ...... ase. 2. Potency and chirality.
@en
P2093
Alan D Borthwick
Andrew J Crame
Andrew M K Pennell
Andrew M Mason
Anne M Exall
Gordon G Weingarten
Graham J Hart
James M Woolven
Onkar M P Singh
Peter F Ertl
P356
10.1021/JM0102203
P407
P577
2002-01-01T00:00:00Z