cGMP-dependent protein kinase I mediates the negative inotropic effect of cGMP in the murine myocardium.
about
Presynaptically localized cyclic GMP-dependent protein kinase 1 is a key determinant of spinal synaptic potentiation and pain hypersensitivityImpairment of LTD and cerebellar learning by Purkinje cell-specific ablation of cGMP-dependent protein kinase IThe cGMP signaling pathway as a therapeutic target in heart failure with preserved ejection fractioncGMP-dependent protein kinase type I is implicated in the regulation of the timing and quality of sleep and wakefulnessPhosphodiesterases and cardiac cGMP: evolving roles and controversiesSequential activation of p38 and ERK pathways by cGMP-dependent protein kinase leading to activation of the platelet integrin alphaIIb beta3IRAG is essential for relaxation of receptor-triggered smooth muscle contraction by cGMP kinaseCatalytic activity of cGMP-dependent protein kinase type I in intact cells is independent of N-terminal autophosphorylationcGMP-dependent protein kinase type I inhibits TAB1-p38 mitogen-activated protein kinase apoptosis signaling in cardiac myocytesEphA7 regulates spiral ganglion innervation of cochlear hair cells.Stress-dependent dilated cardiomyopathy in mice with cardiomyocyte-restricted inactivation of cyclic GMP-dependent protein kinase IRole of phosphodiesterase-5 inhibitors in heart failure: emerging data and concepts.Ex vivo pretreatment of bone marrow mononuclear cells with endothelial NO synthase enhancer AVE9488 enhances their functional activity for cell therapy.cGMP-dependent protein kinase I is crucial for angiogenesis and postnatal vasculogenesisConcerted regulation of cGMP and cAMP phosphodiesterases in early cardiac hypertrophy induced by angiotensin IICardiac hypertrophy is not amplified by deletion of cGMP-dependent protein kinase I in cardiomyocytes.Regulate axon branching by the cyclic GMP pathway via inhibition of glycogen synthase kinase 3 in dorsal root ganglion sensory neurons.Alterations in the cerebellar (Phospho)proteome of a cyclic guanosine monophosphate (cGMP)-dependent protein kinase knockout mouse.cGMP-dependent protein kinase contributes to hydrogen sulfide-stimulated vasorelaxation.Cyclic nucleotide phosphodiesterase PDE1C1 in human cardiac myocytes.Pressure-overload-induced subcellular relocalization/oxidation of soluble guanylyl cyclase in the heart modulates enzyme stimulation.Inhibition of cyclic GMP hydrolysis with zaprinast reduces basal and cyclic AMP-elevated L-type calcium current in guinea-pig ventricular myocytes.Increased effects of C-type natriuretic peptide on contractility and calcium regulation in murine hearts overexpressing cyclic GMP-dependent protein kinase I.sGC{alpha}1 mediates the negative inotropic effects of NO in cardiac myocytes independent of changes in calcium handlingGuanylyl cyclase is an ATP sensor coupling nitric oxide signaling to cell metabolism.Sildenafil preserves diastolic relaxation after reduction by L-NAME and increases phosphodiesterase-5 in the intercalated discs of cardiac myocytes and arteriolesNitric oxide control of cardiac function: is neuronal nitric oxide synthase a key component?Nitric oxide signaling and the regulation of myocardial function.The alpha1 isoform of soluble guanylate cyclase regulates cardiac contractility but is not required for ischemic preconditioningFunction of cGMP-dependent protein kinases in the nervous system.The receptor guanylyl cyclase Npr2 is essential for sensory axon bifurcation within the spinal cord.Direct activation of PDE5 by cGMP: long-term effects within NO/cGMP signalingInhibitors of cyclic nucleotide phosphodiesterase 3 and 5 as therapeutic agents in heart failure.Anemia and splenomegaly in cGKI-deficient mice.A proatherogenic role for cGMP-dependent protein kinase in vascular smooth muscle cells.Phosphodiesterase 5 restricts NOS3/Soluble guanylate cyclase signaling to L-type Ca2+ current in cardiac myocytes.sGC(alpha)1(beta)1 attenuates cardiac dysfunction and mortality in murine inflammatory shock models.Potential novel pharmacological therapies for myocardial remodelling.Endothelial nitric oxide synthase decreases beta-adrenergic responsiveness via inhibition of the L-type Ca2+ currentCyclic GMP signaling in cardiovascular pathophysiology and therapeutics.
P2860
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P2860
cGMP-dependent protein kinase I mediates the negative inotropic effect of cGMP in the murine myocardium.
description
2002 nî lūn-bûn
@nan
2002年の論文
@ja
2002年学术文章
@wuu
2002年学术文章
@zh
2002年学术文章
@zh-cn
2002年学术文章
@zh-hans
2002年学术文章
@zh-my
2002年学术文章
@zh-sg
2002年學術文章
@yue
2002年學術文章
@zh-hant
name
cGMP-dependent protein kinase ...... cGMP in the murine myocardium.
@en
cGMP-dependent protein kinase ...... cGMP in the murine myocardium.
@nl
type
label
cGMP-dependent protein kinase ...... cGMP in the murine myocardium.
@en
cGMP-dependent protein kinase ...... cGMP in the murine myocardium.
@nl
prefLabel
cGMP-dependent protein kinase ...... cGMP in the murine myocardium.
@en
cGMP-dependent protein kinase ...... cGMP in the murine myocardium.
@nl
P2093
P356
P1433
P1476
cGMP-dependent protein kinase ...... cGMP in the murine myocardium.
@en
P2093
Claudia Werner
Franz Hofmann
Hermann Nawrath
Jörg W Wegener
Susanne Kühbandner
Wiebke Wolfsgruber
P356
10.1161/HH0102.103222
P50
P577
2002-01-01T00:00:00Z