Effects of vinblastine, podophyllotoxin and nocodazole on mitotic spindles. Implications for the role of microtubule dynamics in mitosis.
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High content image-based screening of a protease inhibitor library reveals compounds broadly active against Rift Valley fever virus and other highly pathogenic RNA virusesGriseofulvin stabilizes microtubule dynamics, activates p53 and inhibits the proliferation of MCF-7 cells synergistically with vinblastineHEC, a novel nuclear protein rich in leucine heptad repeats specifically involved in mitosisD-TACC: a novel centrosomal protein required for normal spindle function in the early Drosophila embryoMammalian mad2 and bub1/bubR1 recognize distinct spindle-attachment and kinetochore-tension checkpointsMicrotubules do not promote mitotic slippage when the spindle assembly checkpoint cannot be satisfied.Checkpoint genes required to delay cell division in response to nocodazole respond to impaired kinetochore function in the yeast Saccharomyces cerevisiae.Binding of E-MAP-115 to microtubules is regulated by cell cycle-dependent phosphorylationStable hZW10 kinetochore residency, mediated by hZwint-1 interaction, is essential for the mitotic checkpointTaxol suppresses dynamics of individual microtubules in living human tumor cellsThe KinI kinesin Kif2a is required for bipolar spindle assembly through a functional relationship with MCAKReaching out for signals: filopodia sense EGF and respond by directed retrograde transport of activated receptorsKinetochore fiber maturation in PtK1 cells and its implications for the mechanisms of chromosome congression and anaphase onsetDifferential subcellular localization of protein phosphatase-1 alpha, gamma1, and delta isoforms during both interphase and mitosis in mammalian cellsThe human immunodeficiency virus type 1 vpr gene arrests infected T cells in the G2 + M phase of the cell cycleVinca alkaloidsA novel microtubule inhibitor 4SC-207 with anti-proliferative activity in taxane-resistant cellsHow morphological constraints affect axonal polarity in mouse neuronsDarinaparsin is a multivalent chemotherapeutic which induces incomplete stress response with disruption of microtubules and Shh signalingInitiation of Hepatitis C Virus Infection Requires the Dynamic Microtubule Network: ROLE OF THE VIRAL NUCLEOCAPSID PROTEINAurora kinase inhibitors reveal mechanisms of HURP in nucleation of centrosomal and kinetochore microtubulesNAP1 acts with Clb1 to perform mitotic functions and to suppress polar bud growth in budding yeast.The Saccharomyces cerevisiae spindle pole body duplication gene MPS1 is part of a mitotic checkpoint.Antiproliferative mechanism of action of cryptophycin-52: kinetic stabilization of microtubule dynamics by high-affinity binding to microtubule endsInactivation of wild-type p53 by a dominant negative mutant renders MCF-7 cells resistant to tubulin-binding agent cytotoxicityVascular disrupting agent drug classes differ in effects on the cytoskeletonTubulin is a molecular target of the Wnt-activating chemical probeCENP-I and Aurora B act as a molecular switch that ties RZZ/Mad1 recruitment to kinetochore attachment status.Microinjection of mitotic cells with the 3F3/2 anti-phosphoepitope antibody delays the onset of anaphaseMammalian spindle orientation and position respond to changes in cell shape in a dynein-dependent fashion.Human chromokinesins promote chromosome congression and spindle microtubule dynamics during mitosisEvidence for dynein and astral microtubule-mediated cortical release and transport of Gαi/LGN/NuMA complex in mitotic cellsMicrofluidics-integrated time-lapse imaging for analysis of cellular dynamics.Increased microtubule assembly rates influence chromosomal instability in colorectal cancer cells.Alleviation of podophyllotoxin toxicity using coexisting flavonoids from Dysosma versipellis.An experimental and computational study of effects of microtubule stabilization on T-cell polarityThe onconeural antigen cdr2 is a novel APC/C target that acts in mitosis to regulate c-myc target genes in mammalian tumor cells.Tubulin binding cofactor C (TBCC) suppresses tumor growth and enhances chemosensitivity in human breast cancer cellsA novel synthetic analog of 5, 8-disubstituted quinazolines blocks mitosis and induces apoptosis of tumor cells by inhibiting microtubule polymerization.Functional evidence for the involvement of microtubules and dynein motor complexes in TRIM5α-mediated restriction of retroviruses.
P2860
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P2860
Effects of vinblastine, podophyllotoxin and nocodazole on mitotic spindles. Implications for the role of microtubule dynamics in mitosis.
description
1992 nî lūn-bûn
@nan
1992年の論文
@ja
1992年学术文章
@wuu
1992年学术文章
@zh
1992年学术文章
@zh-cn
1992年学术文章
@zh-hans
1992年学术文章
@zh-my
1992年学术文章
@zh-sg
1992年學術文章
@yue
1992年學術文章
@zh-hant
name
Effects of vinblastine, podoph ...... crotubule dynamics in mitosis.
@en
Effects of vinblastine, podoph ...... crotubule dynamics in mitosis.
@nl
type
label
Effects of vinblastine, podoph ...... crotubule dynamics in mitosis.
@en
Effects of vinblastine, podoph ...... crotubule dynamics in mitosis.
@nl
prefLabel
Effects of vinblastine, podoph ...... crotubule dynamics in mitosis.
@en
Effects of vinblastine, podoph ...... crotubule dynamics in mitosis.
@nl
P2093
P1476
Effects of vinblastine, podoph ...... crotubule dynamics in mitosis.
@en
P2093
P304
P407
P478
102 ( Pt 3)
P577
1992-07-01T00:00:00Z